Search Results - "Carle, Georges F."

Autophagy in osteoblasts is involved in mineralization and bone homeostasis by Nollet, Marie, Santucci-Darmanin, Sabine, Breuil, Véronique, Al-Sahlanee, Rasha, Cros, Chantal, Topi, Majlinda, Momier, David, Samson, Michel, Pagnotta, Sophie, Cailleteau, Laurence, Battaglia, Séverine, Farlay, Delphine, Dacquin, Romain, Barois, Nicolas, Jurdic, Pierre, Boivin, Georges, Heymann, Dominique, Lafont, Frank, Lu, Shi Shou, Dempster, David W, Carle, Georges F, Pierrefite-Carle, Valérie

“…Bone remodeling is a tightly controlled mechanism in which osteoblasts (OB), the cells responsible for bone formation, osteoclasts (OC), the cells specialized…”
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Role of autophagy in osteosarcoma by Camuzard, Olivier, Santucci-Darmanin, Sabine, Carle, Georges F., Pierrefite-Carle, Valérie

“…Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. It is a highly aggressive tumor with a tendency to spread to the lungs,…”
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Chelating Polymers for Targeted Decontamination of Actinides: Application of PEI-MP to Hydroxyapatite-Th(IV) by Fèvre, Jeanne, Leveille, Elena, Jeanson, Aurélie, Santucci-Darmanin, Sabine, Pierrefite-Carle, Valérie, Carle, Georges F, Den Auwer, Christophe, Di Giorgio, Christophe

“…In case of an incident in the nuclear industry or an act of war or terrorism, the dissemination of plutonium could contaminate the environment and, hence,…”
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Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability by BELAID, Amine, CEREZO, Michael, BERTOLOTTO, Corinne, BREST, Patrick, VOURET-CRAVIARI, Valérie, KLIONSKY, Daniel J, CARLE, Georges F, HOFMAN, Paul, MOGRABI, Baharia, CHARGUI, Abderrahman, CORCELLE―TERMEAU, Elisabeth, PEDEUTOUR, Florence, GIULIANO, Sandy, ILIE, Marius, RUBERA, Isabelle, TAUC, Michel, BARALE, Sophie

“…Degradation of signaling proteins is one of the most powerful tumor-suppressive mechanisms by which a cell can control its own growth. Here, we identify RHOA…”
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Osteoclast activity modulates B-cell development in the bone marrow by Mansour, Anna, Anginot, Adrienne, Mancini, Stéphane J C, Schiff, Claudine, Carle, Georges F, Wakkach, Abdelilah, Blin-Wakkach, Claudine

“…B-cell development is dependent on the interactions between B-ceU precursors and bone marrow stromal cells, but the role of osteoclasts （OCLs） in this process…”
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Inflammatory blood monocytes contribute to tumor development and represent a privileged target to improve host immunosurveillance by Augier, Séverine, Ciucci, Thomas, Luci, Carmelo, Carle, Georges F, Blin-Wakkach, Claudine, Wakkach, Abdelilah

“…Progressing tumors in humans and mice are frequently infiltrated by a highly heterogeneous population of inflammatory myeloid cells that contribute to tumor…”
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Effect of natural uranium on the UMR-106 osteoblastic cell line: impairment of the autophagic process as an underlying mechanism of uranium toxicity by Pierrefite-Carle, Valérie, Santucci-Darmanin, Sabine, Breuil, Véronique, Gritsaenko, Tatiana, Vidaud, Claude, Creff, Gaelle, Solari, Pier Lorenzo, Pagnotta, Sophie, Al-Sahlanee, Rasha, Auwer, Christophe Den, Carle, Georges F.

“…Natural uranium (U), which is present in our environment, exerts a chemical toxicity, particularly in bone where it accumulates. Generally, U is found at…”
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Sex-specific autophagy modulation in osteoblastic lineage: a critical function to counteract bone loss in female by Camuzard, Olivier, Santucci-Darmanin, Sabine, Breuil, Véronique, Cros, Chantal, Gritsaenko, Tatiana, Pagnotta, Sophie, Cailleteau, Laurence, Battaglia, Séverine, Panaïa-Ferrari, Patricia, Heymann, Dominique, Carle, Georges F, Pierrefite-Carle, Valérie

“…Age-related bone loss is associated with an increased oxidative stress which is worsened by estrogen fall during menauposis. This observation has drawn…”
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Human Primary Osteocyte Differentiation in a 3D Culture System by Boukhechba, Florian, Balaguer, Thierry, Michiels, Jean‐François, Ackermann, Karin, Quincey, Danielle, Bouler, Jean‐Michel, Pyerin, Walter, Carle, Georges F., Rochet, Nathalie

“…Studies on primary osteocytes, which compose >90–95% of bone cells, embedded throughout the mineralized matrix, are a major challenge because of their…”
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Preventive Cancer Stem Cell‐Based Vaccination Reduces Liver Metastasis Development in a Rat Colon Carcinoma Syngeneic Model by Duarte, Sonia, Momier, David, Baqué, Patrick, Casanova, Vincent, Loubat, Agnès, Samson, Michel, Guigonis, Jean‐Marie, Staccini, Pascal, Saint‐Paul, Marie‐Christine, De Lima, Maria Pedroso, Carle, Georges F., Pierrefite‐Carle, Valérie

“…Cancer stem cells (CSCs) represent a minor population of self‐renewing cancer cells that fuel tumor growth. As CSCs are generally spared by conventional…”
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Autophagy in the crosstalk between tumor and microenvironment by Camuzard, Olivier, Santucci-Darmanin, Sabine, Carle, Georges F., Pierrefite-Carle, Valérie

“…Autophagy is the major catabolic process in eukaryotic cells for the degradation and recycling of damaged macromolecules and organelles. It plays a crucial…”
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Differentiation and activity of human preosteoclasts on chitosan enriched calcium phosphate cement by Rochet, Nathalie, Balaguer, Thierry, Boukhechba, Florian, Laugier, Jean-Pierre, Quincey, Danielle, Goncalves, Stéphane, Carle, Georges F

“…Abstract Chitosan associated to various scaffolds has been shown to promote growth and mineral rich matrix deposition by osteoblasts in vitro , whereas its…”
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Fate of bone marrow stromal cells in a syngenic model of bone formation by Boukhechba, Florian, Balaguer, Thierry, Bouvet-Gerbettaz, Sébastien, Michiels, Jean-François, Bouler, Jean-Michel, Carle, Georges F, Scimeca, Jean-Claude, Rochet, Nathalie

“…Bone marrow stromal cells (BMSCs) have been demonstrated to induce bone formation when associated to osteoconductive biomaterials and implanted in vivo…”
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Autophagy in bone: Self-eating to stay in balance by Pierrefite-Carle, Valérie, Santucci-Darmanin, Sabine, Breuil, Véronique, Camuzard, Olivier, Carle, Georges F

“…Highlights • Impaired autophagy in osteoblasts leads to low bone mass phenotype. • Suppression of autophagy in osteocytes mimics skeletal aging. • Autophagy…”
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Specific Expression of BMP2/4 Ortholog in Biomineralizing Tissues of Corals and Action on Mouse BMP Receptor by Zoccola, Didier, Moya, Aurélie, Béranger, Guillaume E, Tambutté, Eric, Allemand, Denis, Carle, Georges F, Tambutté, Sylvie

“…Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β superfamily, and have been identified by their ability to induce bone…”
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Lysosomal exocytosis: From cell protection to protumoral functions by Trojani, Marie-Charlotte, Santucci-Darmanin, Sabine, Breuil, Véronique, Carle, Georges F., Pierrefite-Carle, Valérie

“…Lysosomes are single membrane bounded group of acidic organelles that can be involved in a process called lysosomal exocytosis which leads to the extracellular…”
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Comparison of false starts by saw created on flesh and dry bones; as close as possible to the real conditions of criminal dismemberment by Bernardi, Caroline, Nogueira, Luísa, Amoretti, Nicolas, Carle, Georges F., Alunni, Véronique

“…In most experimental protocols, false starts are produced on dry bones obtained through a maceration process for anthropological analyses, for the sake of…”
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Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect by DUARTE, SÓNIA, LOUBAT, AGNÈS, MOMIER, DAVID, TOPI, MAJLINDA, FANECA, HENRIQUE, PEDROSO DE LIMA, MARIA C, CARLE, GEORGES F, PIERREFITE-CARLE, VALÉRIE

“…The incidence of oral tumors is increasing around the world and despite recent advances in early detection and diagnosis, current treatments are still…”
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Effect of natural uranium on bone cells by Gritsaenko, Tatiana, Hurault, Lucile, Pierrefite-Carle, Valérie, Santucci-Darmanin, Sabine, Pagnotta, Sophie, Vidaud, Claude, Hagège, Agnès, Solari, Pier Lorenzo, Creff, Gaëlle, Den Auwer, Christophe, Carle, Georges F.

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A new in vitro uranium sequestration assay to analyze the effectiveness of 3,4,3-LI(1,2-HOPO) in reducing the harmful effects of this actinide on bone cells by Simoneau, Bastien, Hurault, Lucile, Carle, Georges F., Pierrefite-Carle, Valérie, Santucci-Darmanin, Sabine

“…Environmental or occupational exposure to natural uranium can have adverse health effects, with its chemical toxicity being mainly directed towards the kidneys…”
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