Search Results - "Carla MS Menezes"
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In vitro chloroquine resistance modulation study on fresh isolates of Brazilian Plasmodium falciparum: intrinsic antimalarial activity of phenothiazine drugs
Published in Memórias do Instituto Oswaldo Cruz (01-10-2002)“…Phenothiazine drugs - fluphenazine, chlorpromazine, methotrimeprazine and trifluoperazine - were evaluated as modulating agents against Brazilian…”
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Synthesis, Biological Evaluation, and Structure-activity Relationship of Clonazepam, Meclonazepam, and 1,4-Benzodiazepine Compounds with Schistosomicidal Activity
Published in Chemical biology & drug design (01-06-2012)“…The inherent morbidity and mortality caused by schistosomiasis is a serious public health problem in developing countries. Praziquantel is the only drug in…”
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Study of the interaction between hydroxymethylnitrofurazone and 2-hydroxypropyl-β-cyclodextrin
Published in Journal of pharmaceutical and biomedical analysis (09-06-2008)“…Chagas disease is a serious health problem in Latin America. Hidroxymethylnitrofurazone (NFOH) is a nitrofurazone prodrug more active than nitrofurazone…”
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Molecular modeling and UV–vis spectroscopic studies on the mechanism of action of reversed chloroquine (RCQ)
Published in Bioorganic & medicinal chemistry letters (01-01-2011)“…Molecular modeling and ultraviolet–visible spectroscopy (UV–vis) studies strongly suggest that the interaction between RCQ and heme is predominant through the…”
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Hydroxymethylnitrofurazone:Dimethyl-b-cyclodextrin Inclusion Complex: A Physical-Chemistry Characterization
Published in Journal of biological physics (01-12-2007)“…Hydroxymethylnitrofurazone (NFOH) is active against Trypanosoma cruzi; however, its low solubility and high toxicity precludes its current use in treatment of…”
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In Vitro Chloroquine Resistance Modulation Study on Fresh Isolates of Brazilian Plasmodium falciparum : Intrinsic Antimalarial Activity of Phenothiazine Drugs
Published in Memórias do Instituto Oswaldo Cruz (18-01-2003)“…Phenothiazine drugs - fluphenazine, chlorpromazine, methotrimeprazine and trifluoperazine - were evaluated as modulating agents against Brazilian…”
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Journal Article