Search Results - "Carla MS Menezes"

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    Study of the interaction between hydroxymethylnitrofurazone and 2-hydroxypropyl-β-cyclodextrin by Grillo, Renato, de Melo, Nathalie F.S., Moraes, Carolina Morales, de Lima, Renata, Menezes, Carla M.S., Ferreira, Elizabeth Igne, Rosa, André Henrique, Fraceto, Leonardo Fernandes

    “…Chagas disease is a serious health problem in Latin America. Hidroxymethylnitrofurazone (NFOH) is a nitrofurazone prodrug more active than nitrofurazone…”
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    Journal Article
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    Molecular modeling and UV–vis spectroscopic studies on the mechanism of action of reversed chloroquine (RCQ) by Otelo, Vanessa A., Sant’Ana, Antonio C., de Faria, Dalva L.A., Menezes, Carla M.S.

    Published in Bioorganic & medicinal chemistry letters (01-01-2011)
    “…Molecular modeling and ultraviolet–visible spectroscopy (UV–vis) studies strongly suggest that the interaction between RCQ and heme is predominant through the…”
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    Journal Article
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    Hydroxymethylnitrofurazone:Dimethyl-b-cyclodextrin Inclusion Complex: A Physical-Chemistry Characterization by Grillo, Renato, Melo, Nathalie Ferreira Silva, Moraes, Carolina Morales, Rosa, Andre Henrique, Roveda, Jose Arnaldo Frutuoso, Menezes, Carla MS, Ferreira, Elizabeth Igne, Fraceto, Leonardo Fernandes

    Published in Journal of biological physics (01-12-2007)
    “…Hydroxymethylnitrofurazone (NFOH) is active against Trypanosoma cruzi; however, its low solubility and high toxicity precludes its current use in treatment of…”
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    Journal Article
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