Search Results - "Carl, Henrik"

Targeting the PDGF signaling pathway in tumor treatment by Heldin, Carl-Henrik

“…Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important functions in the regulation of growth and survival of certain cell types…”
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Signaling Receptors for TGF-β Family Members by Heldin, Carl-Henrik, Moustakas, Aristidis

“…Transforming growth factor β (TGF-β) family members signal via heterotetrameric complexes of type I and type II dual specificity kinase receptors. The…”
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Signaling networks guiding epithelial–mesenchymal transitions during embryogenesis and cancer progression by Moustakas, Aristidis, Heldin, Carl‐Henrik

“…Epithelial–mesenchymal transition (EMT) describes the differentiation switch between polarized epithelial cells and contractile and motile mesenchymal cells,…”
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Regulation of EMT by TGFβ in cancer by Heldin, Carl-Henrik, Vanlandewijck, Michael, Moustakas, Aristidis

“…Transforming growth factor-β (TGFβ) suppresses tumor formation since it inhibits cell growth and promotes apoptosis. However, in advanced cancers TGFβ elicits…”
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The regulation of TGFβ signal transduction by Moustakas, Aristidis, Heldin, Carl-Henrik

“…Transforming growth factor β (TGFβ) pathways are implicated in metazoan development, adult homeostasis and disease. TGFβ ligands signal via receptor…”
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Letter to the Editor: Rapid Selective Brain Cooling With PolarCap ® -A Commercial Delusion? by Nordström, Carl-Henrik

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Louis Pasteur—The life of a controversial scientist with a prepared mind, driven by curiosity, motivation, and competition by Brogren, Carl‐Henrik

“…Louis Pasteur, born December 27, 1822 in Dole, France, showed in his childhood and youth great abilities as an artistic painter; however by an age of 19, his…”
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Role of Smads in TGFβ signaling by Heldin, Carl-Henrik, Moustakas, Aristidis

“…Transforming growth factor-β (TGFβ) is the prototype for a large family of pleiotropic factors that signal via heterotetrameric complexes of type I and type II…”
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The structure of nanotubes formed by diphenylalanine, the core recognition motif of Alzheimer's beta-amyloid polypeptide by Görbitz, Carl Henrik

“…Alzheimer's beta-amyloid diphenylalanine motif has previously been shown to self-assemble into discrete and extraordinary stiff nanotubes; these nanotubes were…”
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Microporous Organic Materials from Hydrophobic Dipeptides by Görbitz, Carl Henrik

“…In the last few years dipeptides with two hydrophobic residues (hydrophobic dipeptides) have emerged as an unexpected source of stable microporous organic…”
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Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition by Moustakas, Aristidis, Heldin, Carl-Henrik

“…Transitory phenotypic changes such as the epithelial-mesenchymal transition (EMT) help embryonic cells to generate migratory descendants that populate new…”
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Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors by Sanchez-Duffhues, Gonzalo, Williams, Eleanor, Goumans, Marie-Jose, Heldin, Carl-Henrik, ten Dijke, Peter

“…Bone morphogenetic proteins (BMPs) are secreted cytokines that control the fate and function of many different cell types. They exert their cellular responses…”
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Genome–wide binding of transcription factor ZEB1 in triple‐negative breast cancer cells by Maturi, Varun, Enroth, Stefan, Heldin, Carl‐Henrik, Moustakas, Aristidis

“…Zinc finger E‐box binding homeobox 1 (ZEB1) is a transcriptional regulator involved in embryonic development and cancer progression. ZEB1 induces…”
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Time to antibiotic therapy and outcome in bacterial meningitis: a Danish population-based cohort study by Bodilsen, Jacob, Dalager-Pedersen, Michael, Schønheyder, Henrik Carl, Nielsen, Henrik

“…Community-acquired bacterial meningitis (CABM) is a life-threatening disease and timing of antibiotic therapy remains crucial. We aimed to analyse the impact…”
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Induction of epithelial–mesenchymal transition by transforming growth factor β by Moustakas, Aristidis, Heldin, Carl-Henrik

“…Abstract Transforming growth factor β (TGFβ) is implicated in human malignancy. Tumors may escape the tumor suppressor activity of TGFβ by mutating some of its…”
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Mechanism of TGF-β signaling to growth arrest, apoptosis, and epithelial–mesenchymal transition by Heldin, Carl-Henrik, Landström, Maréne, Moustakas, Aristidis

“…Members of the transforming growth factor-β (TGF-β) family have important roles during embryogenesis, as well as in the control of tissue homeostasis in the…”
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Involvement of hyaluronan and CD44 in cancer and viral infections by Heldin, Paraskevi, Kolliopoulos, Constantinos, Lin, Chun-Yu, Heldin, Carl-Henrik

“…•Hyaluronan is overexpressed in inflammation, infection and cancer and the hyaluronan levels correlate to disease severity.•The hyaluronan receptor CD44…”
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Signals and Receptors by Heldin, Carl-Henrik, Lu, Benson, Evans, Ron, Gutkind, J Silvio

“…Communication between cells in a multicellular organism occurs by the production of ligands (proteins, peptides, fatty acids, steroids, gases, and other…”
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A randomized, double-blind trial comparing the effect of two blood pressure targets on global brain metabolism after out-of-hospital cardiac arrest by Mølstrøm, Simon, Nielsen, Troels Halfeld, Nordstrøm, Carl-Henrik, Forsse, Axel, Møller, Søren, Venø, Søren, Mamaev, Dmitry, Tencer, Tomas, Theódórsdóttir, Ásta, Krøigård, Thomas, Møller, Jacob, Hassager, Christian, Kjærgaard, Jesper, Schmidt, Henrik, Toft, Palle

“…This study aimed to assess the effect of different blood pressure levels on global cerebral metabolism in comatose patients resuscitated from out-of-hospital…”
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Monitoring the near-extinct European weather loach in Denmark based on environmental DNA from water samples by Sigsgaard, Eva Egelyng, Carl, Henrik, Møller, Peter Rask, Thomsen, Philip Francis

“…•eDNA and fishing tools were used to monitor the weather loach in Denmark.•Two localities were positive for loach eDNA, and eight were negative.•Results of…”
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