Search Results - "Carignani, C"
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Characterization of three diaminopyrimidines as potent and selective antagonists of P2X3 and P2X2/3 receptors with in vivo efficacy in a pain model
Published in British journal of pharmacology (01-07-2011)“…BACKGROUND AND PURPOSE P2X3 and P2X2/3 receptors are highly localized on the peripheral and central pathways of nociceptive signal transmission. The discovery…”
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Potent antihyperalgesic activity without tolerance produced by glycine site antagonist of N-methyl-D-aspartate receptor GV196771A
Published in The Journal of pharmacology and experimental therapeutics (01-07-1999)“…Central sensitization is a condition of enhanced excitability of spinal cord neurons that contributes to the exaggerated pain sensation associated with chronic…”
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Pharmacological characterisation of the human small conductance calcium-activated potassium channel hSK3 reveals sensitivity to tricyclic antidepressants and antipsychotic phenothiazines
Published in Neuropharmacology (01-05-2001)“…A stable CHO-K1 cell line was developed which expresses the human small conductance calcium-activated potassium channel hSK3. Immunofluorescence microscopy…”
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Voltage-dependent calcium currents in dissociated granule cells from rat cerebellum
Published in Neuroscience (1991)“…Voltage-dependent calcium currents were investigated by the patch-clamp technique in whole-cell recording configuration in cultures from 8-day-old rat…”
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Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons
Published in The European journal of neuroscience (01-10-2003)“…We investigated the involvement of store‐operated channels (SOCs) and transient receptor potential (TRP) channels in the response to activation of the group I…”
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The antidepressant fluoxetine blocks the human small conductance calcium-activated potassium channels SK1, SK2 and SK3
Published in Neuroscience letters (31-07-2003)“…The effects of fluoxetine (Prozac™) on the activity of human small-conductance calcium-activated potassium (SK) channels were investigated utilizing a…”
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Pharmacological and molecular characterisation of SK3 channels in the TE671 human medulloblastoma cell line
Published in Brain research (07-06-2002)“…The expression of the small conductance calcium-activated potassium channels SK1, SK2 and SK3 was investigated in the TE671 human medulloblastoma cell line…”
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Inhibition of SK3 channels in the TE671 human medulloblastoma cell line by desipramine and imipramine
Published in European journal of pharmacology (19-07-2002)“…The TE671 human medulloblastoma cell line endogenously expresses SK3 channels. Using patch clamp, we tested the effects on this current of desipramine and…”
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Co-Agonism between Glutamate and Glycine on the NMDA Receptor
Published in Annals of the New York Academy of Sciences (01-05-1997)Get full text
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A transient outward current dependent on external calcium in rat cerebellar granule cells
Published in The Journal of membrane biology (01-06-1991)“…The outward potassium current of rat cerebellar granule cells in culture was studied with the whole-cell patch-clamp method. Two voltage-dependent components…”
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A transient voltage-dependent outward current in cultured cerebellar granules
Published in Bioscience reports (01-08-1989)“…Granule cells were dissociated from rat cerebella with a procedure that yields a 98% pure cell population. Potassium currents in these cells were studied using…”
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