Search Results - "Carfi, A."
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Bone mineral density in adults with Down syndrome
Published in Osteoporosis international (01-10-2017)“…Summary This study analyzed data of bone mineral density (BMD) from a large cohort of adults with Down syndrome (DS). BMD was found to decrease with age more…”
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Adults with Down syndrome: a comprehensive approach to manage complexity
Published in Journal of intellectual disability research (01-06-2019)“…Background Down syndrome (DS) is characterised by premature ageing that affects selected organ systems, and persons with this condition can present patterns of…”
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Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases
Published in Proceedings of the National Academy of Sciences - PNAS (30-10-2007)“…Previous findings have suggested that class IIa histone deacetylases (HDACs) (HDAC4, -5, -7, and -9) are inactive on acetylated substrates, thus differing from…”
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The 3‐D structure of a zinc metallo‐beta‐lactamase from Bacillus cereus reveals a new type of protein fold
Published in The EMBO journal (16-10-1995)“…The 3‐D structure of Bacillus cereus (569/H/9) beta‐lactamase (EC 3.5.2.6), which catalyses the hydrolysis of nearly all beta‐lactams, has been solved at 2.5 A…”
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P-057: Association between left ventricular diastolic function and cognitive performance in adults with Down syndrome
Published in European geriatric medicine (01-09-2015)Get full text
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O3.05: Multimorbidity and geriatric conditions in older adults in home care in Europe
Published in European geriatric medicine (01-09-2014)Get full text
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Simple, scalable and robust purification of two HIV-1 subtype C gp120 monomer subunit antigens for phase II clinical trial in Republic of South Africa
Published in Retrovirology (13-09-2012)“…Doc number: P356…”
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O1.12: Down syndrome in adulthood: a disease for geriatricians
Published in European geriatric medicine (01-09-2014)Get full text
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Rationally designed HIV envelope glycoproteins delivered in a novel adjuvant elicited more broadly reactive antigen-specific antibody responses
Published in Retrovirology (13-09-2012)“…Doc number: P18…”
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The New Challenge of Geriatrics: Saving Frail Older People from the SARS-COV-2 Pandemic Infection
Published in The Journal of nutrition, health & aging (01-05-2020)Get full text
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Thyroid Function and its Implications in Oxidative Stress Influencing the Pathogenesis of Osteoporosis in Adults with Down Syndrome: A Cohort Study
Published in Hormone and metabolic research (01-09-2016)“…People with Down syndrome (DS) show lower bone mass density (BMD) and a higher prevalence of hypothyroidism compared to general population. Furthermore, DS is…”
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Assessing and Measuring Chronic Multimorbidity in the Older Population: A Proposal for Its Operationalization
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-10-2017)“…Although the definition of multimorbidity as "the simultaneous presence of two or more chronic diseases" is well established, its operationalization is not yet…”
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Factor associated with SARS-CoV-2 vaccination serological efficacy in adolescents and adults with Down syndrome: data from an international, collaborative initiative of the Trisomy 21 Research SocietyRUNNING TITLE: Factors determining COVID-19 vaccine efficacy in Down syndrome
Published in The Journal of infection (20-02-2023)Get full text
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Comorbidity patterns in institutionalized older adults affected by dementia
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2022)“…Introduction Dementia is common in nursing homes (NH) residents. Defining dementia comorbidities is instrumental to identify groups of persons with dementia…”
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Adverse drug reactions in older adults: a narrative review of the literature
Published in European geriatric medicine (01-06-2021)“…Key summary points Aim To summarize the classification and occurrence of ADRs and identify risk factors and strategies to reduce and prevent ADRs in older…”
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Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor HveA
Published in Molecular cell (01-07-2001)“…Herpes simplex virus (HSV) infection requires binding of the viral envelope glycoprotein D (gD) to cell surface receptors. We report the X-ray structures of a…”
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Preference of Cd(II) and Zn(II) for the Two Metal Sites in Bacillus cereus β-Lactamase II: A Perturbed Angular Correlation of γ-rays Spectroscopic Study
Published in Biochemistry (Easton) (14-12-1999)“…Cd-substituted forms of the Bacillus cereus metallo-β-lactamases (BCII) were studied by perturbed angular correlation of γ-rays (PAC) spectroscopy. At very low…”
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Crystal Structure of the Ebola Virus Membrane Fusion Subunit, GP2, from the Envelope Glycoprotein Ectodomain
Published in Molecular cell (01-11-1998)“…We have determined the structure of GP2 from the Ebola virus membrane fusion glycoprotein by X-ray crystallography. The molecule contains a central…”
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