Search Results - "Carfagna, Nicola"
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Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor
Published in Biological psychiatry (1969) (01-05-2000)“…Background: Reboxetine is a potent antidepressant, with efficacy comparable to that of imipramine, desipramine, and fluoxetine, and has improved side-effect…”
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Neuroprotective effects of nicergoline in immortalized neurons
Published in European journal of pharmacology (05-03-1999)“…We studied the potential neuroprotective action of nicergoline in immortalized hypothalamic GT1-7 cells exposed to agents which deplete levels of reduced…”
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Modulation of hippocampal ACh release by chronic nicergoline treatment in freely moving young and aged rats
Published in Neuroscience letters (15-09-1995)“…The effects of nicergoline on basal and K +-stimulated release of ACh in the hippocampus of 3- and 19-month old rats has been studied by microdialysis. A…”
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Antioxidant properties of MDL and MMDL, two nicergoline metabolites, during chronic administration of haloperidol
Published in European journal of pharmacology (18-10-2002)“…We evaluated the effects of 10-alpha-methoxy-9,10-dihydrolysergol (MDL) and 1-methyl-10-alpha-methoxy-9,10-dihydrolysergol (MMDL), two nicergoline metabolites,…”
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Nicergoline in dementia: A review of its pharmacological properties and therapeutic potential
Published in CNS drugs (01-10-2000)“…Nicergoline is a semisynthetic ergoline derivative indicated for the treatment of cognitive impairment in various forms of dementia. It is currently available…”
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Modulation of phosphoinositide turnover by chronic nicergoline in rat brain
Published in Neuroscience letters (17-05-1996)“…Basal and agonist-stimulated phosphoinositide (PI) turnover and inositol 1,4,5 -trisphospate (InsP 3) content in rat brain were investigated after chronic…”
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Effects of Nicergoline on Age-Related Decrements in Radial Maze Performance and Acetylcholine Levels
Published in Brain research bulletin (1997)“…The effects of chronic oral administration of nicergoline (5.0 mg/kg; bid) on locomotor activity, eight-arm radial maze performance plus striatal, cortical,…”
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(E) and (Z)-3-Styrylpiperidines as sigma ligands
Published in Bioorganic & medicinal chemistry letters (17-06-1997)“…A class of (E) and (Z)-3-styrylpiperidine derivatives was prepared as racemates and evaluated for affinity at σ binding sites labeled with […”
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Preparation of 7-oxaaporphine derivatives and evaluation of their dopaminergic activity
Published in Journal of medicinal chemistry (01-07-1988)“…A series of 7-oxaaporphine derivatives was prepared. The compounds were evaluated as dopaminergic agents. None of them showed either affinity for dopamine…”
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