Search Results - "Carey, Shane M."

Discovery of Strong 3-Nitro-2-Phenyl- 2H -Chromene Analogues as Antitrypanosomal Agents and Inhibitors of Trypanosoma cruzi Glucokinase by Carey, Shane M, O'Neill, Destiny M, Conner, Garrett B, Sherman, Julian, Rodriguez, Ana, D'Antonio, Edward L

“…Chagas disease is one of the world's neglected tropical diseases, caused by the human pathogenic protozoan parasite . There is currently a lack of effective…”
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Novel Tetrazolium-Based Colorimetric Assay for Helicase nsp13 in SARS-CoV-2 by Pham, Triet M., Howard, Morgan G., Carey, Shane M., Baker, Lindsey R., D’Antonio, Edward L.

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a human pathogenic virus that encodes for a helicase (SC2Hel) that is essential for viral…”
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At the outer part of the active site in Trypanosoma cruzi glucokinase: The role of phenylalanine 337 by Carey, Shane M., Kearns, Sean P., Millington, Matthew E., Buechner, Gregory S., Alvarez, Beda E., Daneshian, Leily, Abiskaroon, Brendan, Chruszcz, Maksymilian, D'Antonio, Edward L.

“…The hole mutagenesis approach was used to interrogate the importance of F337 in Trypanosoma cruzi glucokinase (TcGlcK) in order to understand the complete set…”
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Synthesis, biochemical, and biological evaluation of C2 linkage derivatives of amino sugars, inhibitors of glucokinase from Trypanosoma cruzi by Green, Scott B., Lanier, Robert J., Carey, Shane M., Morgan, David R., Gracz, Hanna, Sherman, Julian, Rodriguez, Ana, D'Antonio, Edward L.

“…[Display omitted] •Novel amino sugar analogues were synthesized and purified in a one-step method.•Eighteen amino sugar analogues having either a d-GlcN,…”
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Discovery of Strong 3-Nitro-2-Phenyl-I2H/I-Chromene Analogues as Antitrypanosomal Agents and Inhibitors of ITrypanosoma cruzi/I Glucokinase by Carey, Shane M, O’Neill, Destiny M, Conner, Garrett B, Sherman, Julian, Rodriguez, Ana, D’Antonio, Edward L

“…Chagas disease is one of the world’s neglected tropical diseases, caused by the human pathogenic protozoan parasite Trypanosoma cruzi. There is currently a…”
Get full text