Search Results - "Carey, Megan E"
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Exploiting genomics to mitigate the public health impact of antimicrobial resistance
Published in Genome medicine (16-02-2022)“…Antimicrobial resistance (AMR) is a major global public health threat, which has been largely driven by the excessive use of antimicrobials. Control measures…”
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Whole genome sequence analysis of Salmonella Typhi provides evidence of phylogenetic linkage between cases of typhoid fever in Santiago, Chile in the 1980s and 2010–2016
Published in PLoS neglected tropical diseases (29-06-2022)“…Typhoid fever epidemiology was investigated rigorously in Santiago, Chile during the 1980s, when Salmonella enterica serovar Typhi ( S . Typhi) caused…”
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A Race against Time: Reduced Azithromycin Susceptibility in Salmonella enterica Serovar Typhi in Pakistan
Published in mSphere (22-07-2020)“…Antimicrobial resistance is an ongoing issue in the treatment of typhoid fever. Resistance to first-line antimicrobials and extensively drug resistant (XDR)…”
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A genomic snapshot of Salmonella enterica serovar Typhi in Colombia
Published in PLoS neglected tropical diseases (01-09-2021)“…Little is known about the genetic diversity of Salmonella enterica serovar Typhi (S. Typhi) circulating in Latin America. It has been observed that typhoid…”
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The genomic diversity and antimicrobial resistance of Non-typhoidal Salmonella in humans and food animals in Northern India
Published in One health (01-12-2024)“…Non-typhoidal Salmonella (NTS) serovars are the leading global cause of gastroenteritis and have established reservoirs in food animals. Due to a lack of…”
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The origins of haplotype 58 (H58) Salmonella enterica serovar Typhi
Published in Communications biology (28-06-2024)“…Antimicrobial resistance (AMR) poses a serious threat to the clinical management of typhoid fever. AMR in Salmonella Typhi ( S . Typhi) is commonly associated…”
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The Challenge Non-Typhoidal Salmonella (CHANTS) Consortium: Development of a non-typhoidal Salmonella controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK
Published in Wellcome open research (2023)“…Invasive non-typhoidal disease (iNTS) is a major cause of morbidity and mortality globally, particularly as a cause of bloodstream infection in children and…”
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The rotavirus vaccine development pipeline
Published in Vaccine (28-11-2019)“…Graphical abstract…”
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Typhoid fever control in the 21st century: where are we now?
Published in Current opinion in infectious diseases (01-10-2022)“…Momentum for achieving widespread control of typhoid fever has been growing over the past decade. Typhoid conjugate vaccines represent a potentially effective…”
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The Severe Typhoid Fever in Africa Program Highlights the Need for Broad Deployment of Typhoid Conjugate Vaccines
Published in Clinical infectious diseases (30-10-2019)“…The Typhoid Surveillance in Africa Program (TSAP) and the Severe Typhoid Fever in Africa (SETA) program have refined our understanding of age and geographic…”
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Spontaneous Emergence of Azithromycin Resistance in Independent Lineages of Salmonella Typhi in Northern India
Published in Clinical infectious diseases (01-03-2021)“…Abstract Background The emergence and spread of antimicrobial resistance (AMR) pose a major threat to the effective treatment and control of typhoid fever. The…”
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Challenges and Opportunities for Typhoid Fever Control: A Call for Coordinated Action
Published in Clinical infectious diseases (15-03-2016)“…The burden of enteric fever caused by Salmonella enterica serovars Typhi and Paratyphi is substantial and has high impact in toddlers and young children. This…”
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The Surveillance for Enteric Fever in Asia Project (SEAP), Severe Typhoid Fever Surveillance in Africa (SETA), Surveillance of Enteric Fever in India (SEFI), and Strategic Typhoid Alliance Across Africa and Asia (STRATAA) Population-based Enteric Fever Studies: A Review of Methodological Similarities and Differences
Published in Clinical infectious diseases (29-07-2020)“…Abstract Building on previous multicountry surveillance studies of typhoid and others salmonelloses such as the Diseases of the Most Impoverished program and…”
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The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study
Published in The Lancet. Microbe (01-08-2022)“…The emergence of increasingly antimicrobial-resistant Salmonella enterica serovar Typhi (S Typhi) threatens to undermine effective treatment and control…”
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Typhoid Conjugate Vaccines and Enteric Fever Control: Where to Next?
Published in Clinical infectious diseases (29-07-2020)“…Abstract After the unprecedented success and acceleration of the global agenda towards typhoid fever control with a strong World Health Organization…”
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Toward Control? The Prospects and Challenges of Typhoid Conjugate Vaccine Introduction
Published in Clinical infectious diseases (15-10-2019)“…With a newly World Health Organization (WHO)-prequalified typhoid conjugate vaccine (TCV), Gavi funding for eligible countries, and a WHO policy recommendation…”
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Using Typhoid Conjugate Vaccines to Prevent Disease, Promote Health Equity, and Counter Drug-Resistant Typhoid Fever
Published in Open forum infectious diseases (02-06-2023)“…Abstract Typhoid fever is a serious disease that disproportionately impacts children in low-resource settings in sub-Saharan Africa, South and Southeast Asia,…”
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A Global Agenda for Typhoid Control—A Perspective from the Bill & Melinda Gates Foundation
Published in Clinical infectious diseases (15-02-2019)“…Abstract Recognizing that enteric fever disproportionately affects the poorest and the most vulnerable communities that have limited access to improved…”
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Unlocking the Potential of Genomic Data to Inform Typhoid Fever Control Policy: Supportive Resources for Genomic Data Generation, Analysis, and Visualization
Published in Open forum infectious diseases (02-06-2023)“…Abstract The global response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic demonstrated the value of timely and open sharing of…”
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