Search Results - "Carey, Kirstyn T."

Regulatory Potential of the RNA Processing Machinery: Implications for Human Disease by Carey, Kirstyn T., Wickramasinghe, Vihandha O.

“…Splicing and nuclear export of mRNA are critical steps in the gene expression pathway. While RNA processing factors can perform general, essential functions…”
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Glucocorticoids Stimulate Hepatic and Renal Catecholamine Inactivation by Direct Rapid Induction of the Dopamine Sulfotransferase Sult1d1 by Wong, Stephen, Tan, Kheng, Carey, Kirstyn T, Fukushima, Atsushi, Tiganis, Tony, Cole, Timothy J

“…During the stress response and metabolic fasting, glucocorticoids acting via the glucocorticoid receptor (GR) stimulate hepatic glucose production by…”
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Loss of the Mitochondrial Fatty Acid β-Oxidation Protein Medium-Chain Acyl-Coenzyme A Dehydrogenase Disrupts Oxidative Phosphorylation Protein Complex Stability and Function by Lim, Sze Chern, Tajika, Makiko, Shimura, Masaru, Carey, Kirstyn T., Stroud, David A., Murayama, Kei, Ohtake, Akira, McKenzie, Matthew

“…Medium-chain acyl-Coenzyme A dehydrogenase (MCAD) is involved in the initial step of mitochondrial fatty acid β-oxidation (FAO). Loss of function results in…”
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Nuclear export of circular RNA by Ngo, Linh H., Bert, Andrew G., Dredge, B. Kate, Williams, Tobias, Murphy, Vincent, Li, Wanqiu, Hamilton, William B., Carey, Kirstyn T., Toubia, John, Pillman, Katherine A., Liu, Dawei, Desogus, Jessica, Chao, Jeffrey A., Deans, Andrew J., Goodall, Gregory J., Wickramasinghe, Vihandha O.

“…Circular RNAs (circRNAs), which are increasingly being implicated in a variety of functions in normal and cancerous cells 1 – 5 , are formed by back-splicing…”
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Publisher Correction: Nuclear export of circular RNA by Ngo, Linh H., Bert, Andrew G., Dredge, B. Kate, Williams, Tobias, Murphy, Vincent, Li, Wanqiu, Hamilton, William B., Carey, Kirstyn T., Toubia, John, Pillman, Katherine A., Liu, Dawei, Desogus, Jessica, Chao, Jeffrey A., Deans, Andrew J., Goodall, Gregory J., Wickramasinghe, Vihandha O.

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Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: ubiquinone oxidoreductase (Complex I) by Lim, Sze Chern, Carey, Kirstyn T, McKenzie, Matthew

“…Isoflavonoids have been shown to inhibit tumor proliferation and metastasis by activating cell death pathways. As such, they have been widely studied as…”
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Modulation of ceramide-induced cell death and superoxide production by mitochondrial DNA-encoded respiratory chain defects in Rattus xenocybrid mouse cells by Trounce, Ian A., Crouch, Peter J., Carey, Kirstyn T., McKenzie, Matthew

“…Mitochondria play an integral role in cell death signaling, yet how mitochondrial defects disrupt this important function is not well understood. We have used…”
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Nfil3 Is a Glucocorticoid-Regulated Gene Required for Glucocorticoid-Induced Apoptosis in Male Murine T Cells by Carey, Kirstyn T, Tan, Kheng H, Ng, Judy, Liddicoat, Douglas R, Godfrey, Dale I, Cole, Timothy J

“…Glucocorticoids (GCs) have essential roles in the regulation of development, integrated metabolism, and immune and neurological responses, and act primarily…”
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Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice by Chappaz, Stéphane, Law, Charity W., Dowling, Mark R., Carey, Kirstyn T., Lane, Rachael M., Ngo, Linh H., Wickramasinghe, Vihandha O., Smyth, Gordon K., Ritchie, Matthew E., Kile, Benjamin T.

“…In eukaryotic cells, messenger RNA (mRNA) molecules are exported from the nucleus to the cytoplasm, where they are translated. The highly conserved protein…”
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