Search Results - "Carey, Caitlin E."

Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential by Bogdan, Ryan, Salmeron, Betty Jo, Carey, Caitlin E, Agrawal, Arpana, Calhoun, Vince D, Garavan, Hugh, Hariri, Ahmad R, Heinz, Andreas, Hill, Matthew N, Holmes, Andrew, Kalin, Ned H, Goldman, David

“…Abstract Imaging genetics and genomics research has begun to provide insight into the molecular and genetic architecture of neural phenotypes and the neural…”
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The impact of non-additive genetic associations on age-related complex diseases by Guindo-Martínez, Marta, Amela, Ramon, Bonàs-Guarch, Silvia, Puiggròs, Montserrat, Salvoro, Cecilia, Miguel-Escalada, Irene, Carey, Caitlin E., Cole, Joanne B., Rüeger, Sina, Atkinson, Elizabeth, Leong, Aaron, Sanchez, Friman, Ramon-Cortes, Cristian, Ejarque, Jorge, Palmer, Duncan S., Kurki, Mitja, Aragam, Krishna, Florez, Jose C., Badia, Rosa M., Mercader, Josep M., Torrents, David

“…Genome-wide association studies (GWAS) are not fully comprehensive, as current strategies typically test only the additive model, exclude the X chromosome, and…”
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Association between substance use disorder and polygenic liability to schizophrenia by Hartz, Sarah M., MD PhD, Horton, Amy, PhD, Oehlert, Mary, PhD, Carey, Caitlin E., MA, Agrawal, Arpana, PhD, Bogdan, Ryan, PhD, Chen, Li-Shiun, MD MSc, Hancock, Dana B., PhD, Johnson, Eric O., PhD, Pato, Carlos, MD, Pato, Michele, MD, Rice, John P., PhD, Bierut, Laura J., MD

“…Abstract Background There are high levels of comorbidity between schizophrenia and substance use disorder, but little is known about the genetic etiology of…”
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Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement by Carey, Caitlin E, Agrawal, Arpana, Bucholz, Kathleen K, Hartz, Sarah M, Lynskey, Michael T, Nelson, Elliot C, Bierut, Laura J, Bogdan, Ryan

“…Despite evidence of substantial comorbidity between psychiatric disorders and substance involvement, the extent to which common genetic factors contribute to…”
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The female protective effect against autism spectrum disorder by Wigdor, Emilie M., Weiner, Daniel J., Grove, Jakob, Fu, Jack M., Thompson, Wesley K., Carey, Caitlin E., Baya, Nikolas, van der Merwe, Celia, Walters, Raymond K., Satterstrom, F. Kyle, Palmer, Duncan S., Rosengren, Anders, Bybjerg-Grauholm, Jonas, Hougaard, David M., Mortensen, Preben Bo, Daly, Mark J., Talkowski, Michael E., Sanders, Stephan J., Bishop, Somer L., Børglum, Anders D., Robinson, Elise B.

“…Autism spectrum disorder (ASD) is diagnosed three to four times more frequently in males than in females. Genetic studies of rare variants support a female…”
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PER1 rs3027172 Genotype Interacts with Early Life Stress to Predict Problematic Alcohol Use, but Not Reward-Related Ventral Striatum Activity by Baranger, David A A, Ifrah, Chloé, Prather, Aric A, Carey, Caitlin E, Corral-Frías, Nadia S, Drabant Conley, Emily, Hariri, Ahmad R, Bogdan, Ryan

“…Increasing evidence suggests that the circadian and stress regulatory systems contribute to alcohol use disorder (AUD) risk, which may partially arise through…”
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Patterns of item nonresponse behaviour to survey questionnaires are systematic and associated with genetic loci by Mignogna, Gianmarco, Carey, Caitlin E., Wedow, Robbee, Baya, Nikolas, Cordioli, Mattia, Pirastu, Nicola, Bellocco, Rino, Malerbi, Kathryn Fiuza, Nivard, Michel G., Neale, Benjamin M., Walters, Raymond K., Ganna, Andrea

“…Response to survey questionnaires is vital for social and behavioural research, and most analyses assume full and accurate response by participants. However,…”
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A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex by Antaki, Danny, Guevara, James, Maihofer, Adam X., Klein, Marieke, Gujral, Madhusudan, Grove, Jakob, Carey, Caitlin E., Hong, Oanh, Arranz, Maria J., Hervas, Amaia, Corsello, Christina, Vaux, Keith K., Muotri, Alysson R., Iakoucheva, Lilia M., Courchesne, Eric, Pierce, Karen, Gleeson, Joseph G., Robinson, Elise B., Nievergelt, Caroline M., Sebat, Jonathan

“…The genetic etiology of autism spectrum disorder (ASD) is multifactorial, but how combinations of genetic factors determine risk is unclear. In a large family…”
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Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations by Peterson, Roseann E., Kuchenbaecker, Karoline, Walters, Raymond K., Chen, Chia-Yen, Popejoy, Alice B., Periyasamy, Sathish, Lam, Max, Iyegbe, Conrad, Strawbridge, Rona J., Brick, Leslie, Carey, Caitlin E., Martin, Alicia R., Meyers, Jacquelyn L., Su, Jinni, Chen, Junfang, Edwards, Alexis C., Kalungi, Allan, Koen, Nastassja, Majara, Lerato, Schwarz, Emanuel, Smoller, Jordan W., Stahl, Eli A., Sullivan, Patrick F., Vassos, Evangelos, Mowry, Bryan, Prieto, Miguel L., Cuellar-Barboza, Alfredo, Bigdeli, Tim B., Edenberg, Howard J., Huang, Hailiang, Duncan, Laramie E.

“…Genome-wide association studies (GWASs) have focused primarily on populations of European descent, but it is essential that diverse populations become better…”
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Executive Function and Genomic Risk for Attention-Deficit/Hyperactivity Disorder: Testing Intermediate Phenotypes in the Context of Polygenic Risk by Carey, Caitlin E., Bogdan, Ryan

“…Attention-deficit/hyperactivity disorder (ADHD) is associated with cognitive, academic, and socio-emotional deficits in childhood that foreshadow a greater…”
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Pattern Similarity Analyses of FrontoParietal Task Coding: Individual Variation and Genetic Influences by Etzel, Joset A, Courtney, Ya’el, Carey, Caitlin E, Gehred, Maria Z, Agrawal, Arpana, Braver, Todd S

“…Abstract Pattern similarity analyses are increasingly used to characterize coding properties of brain regions, but relatively few have focused on cognitive…”
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Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups by Mattheisen, Manuel, Grove, Jakob, Als, Thomas D., Martin, Joanna, Voloudakis, Georgios, Meier, Sandra, Demontis, Ditte, Bendl, Jaroslav, Walters, Raymond, Carey, Caitlin E., Rosengren, Anders, Strom, Nora I., Hauberg, Mads Engel, Zeng, Biao, Hoffman, Gabriel, Zhang, Wen, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Agerbo, Esben, Cormand, Bru, Nordentoft, Merete, Werge, Thomas, Mors, Ole, Hougaard, David M., Buxbaum, Joseph D., Faraone, Stephen V., Franke, Barbara, Dalsgaard, Søren, Mortensen, Preben B., Robinson, Elise B., Roussos, Panos, Neale, Benjamin M., Daly, Mark J., Børglum, Anders D.

“…Attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are highly heritable neurodevelopmental conditions, with considerable…”
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Hypothalamic-Pituitary-Adrenal Axis Genetic Variation and Early Stress Moderates Amygdala Function by Iorio, Christina R. Di, Carey, Caitlin E, Michalski, Lindsay J, Corral-Frias, Nadia S, Conley, Emily Drabant, Hariri, Ahmad R, Bogdan, Ryan

“…Highlights • HPA axis genetic profile and early life stress interact to predict amygdala function. • HPA axis genetic profile is associated with anxiety…”
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Genome‐wide association studies of alcohol dependence, DSM‐IV criterion count and individual criteria by Lai, Dongbing, Wetherill, Leah, Bertelsen, Sarah, Carey, Caitlin E., Kamarajan, Chella, Kapoor, Manav, Meyers, Jacquelyn L., Anokhin, Andrey P., Bennett, David A., Bucholz, Kathleen K., Chang, Katharine K., De Jager, Philip L., Dick, Danielle M., Hesselbrock, Victor, Kramer, John, Kuperman, Samuel, Nurnberger, John I., Raj, Towfique, Schuckit, Marc, Scott, Denise M., Taylor, Robert E., Tischfield, Jay, Hariri, Ahmad R., Edenberg, Howard J., Agrawal, Arpana, Bogdan, Ryan, Porjesz, Bernice, Goate, Alison M., Foroud, Tatiana

“…Genome‐wide association studies (GWAS) of alcohol dependence (AD) have reliably identified variation within alcohol metabolizing genes (eg, ADH1B) but have…”
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Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex by Antaki, Danny, Guevara, James, Maihofer, Adam X., Klein, Marieke, Gujral, Madhusudan, Grove, Jakob, Carey, Caitlin E., Hong, Oanh, Arranz, Maria J., Hervas, Amaia, Corsello, Christina, Vaux, Keith K., Muotri, Alysson R., Iakoucheva, Lilia M., Courchesne, Eric, Pierce, Karen, Gleeson, Joseph G., Robinson, Elise B., Nievergelt, Caroline M., Sebat, Jonathan

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Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation by Carey, Caitlin E., Shafee, Rebecca, Wedow, Robbee, Elliott, Amanda, Palmer, Duncan S., Compitello, John, Kanai, Masahiro, Abbott, Liam, Schultz, Patrick, Karczewski, Konrad J., Bryant, Samuel C., Cusick, Caroline M., Churchhouse, Claire, Howrigan, Daniel P., King, Daniel, Davey Smith, George, Neale, Benjamin M., Walters, Raymond K., Robinson, Elise B.

“…Data within biobanks capture broad yet detailed indices of human variation, but biobank-wide insights can be difficult to extract due to complexity and scale…”
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Reward-related ventral striatum activity links polygenic risk for attention-deficit/hyperactivity disorder to problematic alcohol use in young adulthood by Carey, Caitlin E, Knodt, Annchen R, Conley, Emily Drabant, Hariri, Ahmad R, Bogdan, Ryan

“…Abstract Background Problematic alcohol use in adolescence and adulthood is a common and often debilitating correlate of childhood…”
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Monoacylglycerol Lipase (MGLL) Polymorphism rs604300 Interacts With Childhood Adversity to Predict Cannabis Dependence Symptoms and Amygdala Habituation: Evidence From an Endocannabinoid System-Level Analysis by Carey, Caitlin E., Agrawal, Arpana, Zhang, Bo, Conley, Emily D., Degenhardt, Louisa, Heath, Andrew C., Li, Daofeng, Lynskey, Michael T., Martin, Nicholas G., Montgomery, Grant W., Wang, Ting, Bierut, Laura J., Hariri, Ahmad R., Nelson, Elliot C., Bogdan, Ryan

“…Despite evidence for heritable variation in cannabis involvement and the discovery of cannabinoid receptors and their endogenous ligands, no consistent…”
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Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism by Satterstrom, F. Kyle, Breen, Michael S., Grove, Jakob, Klei, Lambertus, Xu, Xinyi, Norman, Utku, Brand, Harrison, Schwartz, Grace, Barbosa, Mafalda, Bybjerg-Grauholm, Jonas, Carracedo, Angel, Chiocchetti, Andreas G., Chung, Brian H.Y., Coon, Hilary, Cuccaro, Michael L., Dalla Bernardina, Bernardo, Domenici, Enrico, Dong, Shan, Freitag, Christine M., González-Peñas, Javier, Guter, Stephen, He, Xin, Herman, Gail E., Hertz-Picciotto, Irva, Hougaard, David M., Ionita-Laza, Iuliana, Jacob, Suma, Jamison, Jesslyn, Jugessur, Astanand, Kolevzon, Alexander, Kushima, Itaru, Lee, So Lun, Lehtimäki, Terho, Lim, Elaine T., Lipkin, W. Ian, Lopergolo, Diego, Lopes, Fátima, Ludena, Yunin, Maciel, Patricia, Meiri, Gal, Menashe, Idan, Miller, Judith, Montenegro, Eduarda M.S., Muglia, Pierandrea, Nordentoft, Merete, Ozaki, Norio, Palotie, Aarno, Parellada, Mara, Passos-Bueno, Maria Rita, Persico, Antonio M., Pessah, Isaac, Puura, Kaija, Renieri, Alessandra, Riberi, Evelise, Robinson, Elise B., Samocha, Kaitlin E., Sandin, Sven, Santangelo, Susan L., Schellenberg, Gerry, Scherer, Stephen W., Schmitt, Lauren, Silva, Isabela M.W., Singh, Tarjinder, Siper, Paige M., Soares, Gabriela, Susser, Ezra, Szatmari, Peter, Tang, Lara, Tassone, Flora, Teufel, Karoline, Trelles, Maria del Pilar, Werge, Thomas, Werling, Donna M., Wigdor, Emilie M., Yu, Mullin H.C., Zachi, Elaine, Agerbo, Esben, Als, Thomas Damm, Bækvad-Hansen, Marie, Belliveau, Rich, Cerrato, Felecia, Chambert, Kimberly, Churchhouse, Claire, Dumont, Ashley, Hansen, Christine S., Hauberg, Mads Engel, Hollegaard, Mads V., Howrigan, Daniel P., Maller, Julian, Mattheisen, Manuel, Moran, Jennifer, Pallesen, Jonatan, Poulsen, Jesper Buchhave, Ripke, Stephan, Gallagher, Louise, Gill, Michael, Zwick, Michael E., State, Matthew W., Daly, Mark J., Buxbaum, Joseph D.

“…We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n = 35,584 total samples, 11,986 with ASD). Using an enhanced…”
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Genetic analyses identify widespread sex-differential participation bias by Pirastu, Nicola, Cordioli, Mattia, Nandakumar, Priyanka, Mignogna, Gianmarco, Abdellaoui, Abdel, Hollis, Benjamin, Kanai, Masahiro, Rajagopal, Veera M., Parolo, Pietro Della Briotta, Baya, Nikolas, Carey, Caitlin E., Karjalainen, Juha, Als, Thomas D., Van der Zee, Matthijs D., Day, Felix R., Ong, Ken K., Morisaki, Takayuki, de Geus, Eco, Bellocco, Rino, Okada, Yukinori, Børglum, Anders D., Joshi, Peter, Auton, Adam, Hinds, David, Neale, Benjamin M., Walters, Raymond K., Nivard, Michel G., Perry, John R. B., Ganna, Andrea

“…Genetic association results are often interpreted with the assumption that study participation does not affect downstream analyses. Understanding the genetic…”
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