Search Results - "Carere, Jason"

Patulin in Apples and Apple-Based Food Products: The Burdens and the Mitigation Strategies by Zhong, Lei, Carere, Jason, Lu, Zhaoxin, Lu, Fengxia, Zhou, Ting

“…Apples and apple-based products are among the most popular foods around the world for their delightful flavors and health benefits. However, the commonly found…”
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The enzymatic detoxification of the mycotoxin deoxynivalenol: identification of DepA from the DON epimerization pathway by Carere, Jason, Hassan, Yousef I., Lepp, Dion, Zhou, Ting

“…Summary The biological detoxification of mycotoxins, including deoxynivalenol (DON), represents a very promising approach to address the challenging problem of…”
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The Identification of DepB: An Enzyme Responsible for the Final Detoxification Step in the Deoxynivalenol Epimerization Pathway in Devosia mutans 17-2-E-8 by Carere, Jason, Hassan, Yousef I, Lepp, Dion, Zhou, Ting

“…Deoxynivalenol (DON) is one of the most common mycotoxins found in cereal grains and grains contaminated with DON can cause health issues for both humans and…”
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Structure–function characterization of an aldo–keto reductase involved in detoxification of the mycotoxin, deoxynivalenol by Abraham, Nadine, Schroeter, Kurt L., Zhu, Yan, Chan, Jonathan, Evans, Natasha, Kimber, Matthew S., Carere, Jason, Zhou, Ting, Seah, Stephen Y. K.

“…Deoxynivalenol (DON) is a mycotoxin, produced by filamentous fungi such as Fusarium graminearum , that causes significant yield losses of cereal grain crops…”
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The cereal pathogen Fusarium pseudograminearum produces a new class of active cytokinins during infection by Sørensen, Jens Laurids, Benfield, Aurelie H., Wollenberg, Rasmus Dam, Westphal, Klaus, Wimmer, Reinhard, Nielsen, Mikkel Rank, Nielsen, Kristian Fog, Carere, Jason, Covarelli, Lorenzo, Beccari, Giovanni, Powell, Jonathan, Yamashino, Takafumi, Kogler, Herbert, Sondergaard, Teis Esben, Gardiner, Donald Max

“…Summary The fungal pathogen Fusarium pseudograminearum causes important diseases of wheat and barley. During a survey of secondary metabolites produced by this…”
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Unveiling the Broad Substrate Specificity of Deoxynivalenol Oxidation Enzyme DepA and Its Role in Detoxifying Trichothecene Mycotoxins by Zhu, Yan, Chan, Edicon Tze Shun, Abraham, Nadine, Li, Xiu-Zhen, Wang, Weijun, Mats, Lili, Zhu, Honghui, Carere, Jason, Zhou, Ting

“…DepA, a pyrroloquinoline quinone (PQQ)-dependent enzyme isolated from mutans 17-2-E-8, exhibits versatility in oxidizing deoxynivalenol (DON) and its…”
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Enzyme-driven metabolomic screening: a proof-of-principle method for discovery of plant defence compounds targeted by pathogens by Carere, Jason, Colgrave, Michelle L., Stiller, Jiri, Liu, Chunji, Manners, John M., Kazan, Kemal, Gardiner, Donald M.

“…Plants produce a variety of secondary metabolites to defend themselves from pathogen attack, while pathogens have evolved to overcome plant defences by…”
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Formation of glutathione patulin conjugates associated with yeast fermentation contributes to patulin reduction by Zhong, Lei, Carere, Jason, Mats, Lili, Lu, Zhaoxin, Lu, Fengxia, Zhou, Ting

“…Patulin (PAT) is a fungal secondary metabolite which is mainly detected in rotten apples, and possesses serious risks to human health. Saccharomyces cerevisiae…”
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A Novel PilR/PilS Two-Component System Regulates Necrotic Enteritis Pilus Production in Clostridium perfringens by Zhou, Yuanyuan, Lepp, Dion, Carere, Jason, Yu, Hai, Yang, Chengbo, Gong, Joshua

“…Clostridium perfringens causes necrotic enteritis (NE) in poultry. A chromosomal locus (VR-10B) was previously identified in NE-causing C. perfringens strains…”
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The Fusarium crown rot pathogen Fusarium pseudograminearum triggers a suite of transcriptional and metabolic changes in bread wheat (Triticum aestivum L.) by Powell, Jonathan J., Carere, Jason, Fitzgerald, Timothy L., Stiller, Jiri, Covarelli, Lorenzo, Xu, Qian, Gubler, Frank, Colgrave, Michelle L., Gardiner, Donald M., Manners, John M., Henry, Robert J., Kazan, Kemal

“…Fusarium crown rot caused by the fungal pathogen Fusarium pseudograminearum is a disease of wheat and barley, bearing significant economic cost. Efforts to…”
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BdACT2a encodes an agmatine coumaroyl transferase required for pathogen defence in Brachypodium distachyon by Carere, Jason, Powell, Jonathan, Fitzgerald, Timothy, Kazan, Kemal, Gardiner, Donald M.

“…Plants have a variety of enzymes which help defend from pathogen attack by producing antimicrobial compounds. One of these enzymes, agmatine coumaroyl…”
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Transcriptome analysis of Brachypodium during fungal pathogen infection reveals both shared and distinct defense responses with wheat by Powell, Jonathan J., Carere, Jason, Sablok, Gaurav, Fitzgerald, Timothy L., Stiller, Jiri, Colgrave, Michelle L., Gardiner, Donald M., Manners, John M., Vogel, John P., Henry, Robert J., Kazan, Kemal

“…Fusarium crown rot (FCR) of wheat and barley, predominantly caused by the fungal pathogen Fusarium pseudograminearum , is a disease of economic significance…”
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A γ-lactamase from cereal infecting Fusarium spp. catalyses the first step in the degradation of the benzoxazolinone class of phytoalexins by Kettle, Andrew J., Carere, Jason, Batley, Jacqueline, Benfield, Aurelie H., Manners, John M., Kazan, Kemal, Gardiner, Donald M.

“…•Fdb1, a γ-lactamase, identified and functionally characterised in Fusarium spp.•Fdb1 converts the benzoxazolinone class phytoalexins to aminophenols.•Deletion…”
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A tomatinase-like enzyme acts as a virulence factor in the wheat pathogen Fusarium graminearum by Carere, Jason, Benfield, Aurélie H, Ollivier, Mélodie, Liu, Chunji J, Kazan, Kemal, Gardiner, Donald M

“…During their interactions with plants, fungal pathogens employ large numbers of pathogenesis-associated molecules including secreted effectors and enzymes that…”
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Characterization of an Aldolase–Dehydrogenase Complex from the Cholesterol Degradation Pathway of Mycobacterium tuberculosis by Carere, Jason, McKenna, Sarah E, Kimber, Matthew S, Seah, Stephen Y. K

“…HsaF and HsaG are an aldolase and dehydrogenase from the cholesterol degradation pathway of Mycobacterium tuberculosis. HsaF could be heterologously expressed…”
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The Fdb3 transcription factor of the Fusarium Detoxification of Benzoxazolinone gene cluster is required for MBOA but not BOA degradation in Fusarium pseudograminearum by Kettle, Andrew J., Carere, Jason, Batley, Jacqueline, Manners, John M., Kazan, Kemal, Gardiner, Donald M.

“…•Fdb3 transcription factor is essential for 6-methoxybenzoxazolinone detoxification.•Fdb3 contributes quantitatively to benzoxazolinone (BOA)…”
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Investigating the Molecular Determinants for Substrate Channeling in BphI–BphJ, an Aldolase–Dehydrogenase Complex from the Polychlorinated Biphenyls Degradation Pathway by Carere, Jason, Baker, Perrin, Seah, Stephen Y. K

“…BphI–BphJ, an aldolase–dehydrogenase complex from the polychlorinated biphenyls (PCBs) degradation pathway, cleaves 4-hydroxy-2-oxoacids to pyruvate and an…”
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Protein–Protein Interactions and Substrate Channeling in Orthologous and Chimeric Aldolase–Dehydrogenase Complexes by Baker, Perrin, Hillis, Colleen, Carere, Jason, Seah, Stephen Y. K

“…Bacterial aldolase–dehydrogenase complexes catalyze the last steps in the meta cleavage pathway of aromatic hydrocarbon degradation. The aldolase (TTHB246) and…”
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Probing the Molecular Basis of Substrate Specificity, Stereospecificity, and Catalysis in the Class II Pyruvate Aldolase, BphI by Baker, Perrin, Carere, Jason, Seah, Stephen Y. K

“…BphI, a pyruvate-specific class II aldolase found in the polychlorinated biphenyls (PCBs) degradation pathway, catalyzes the reversible C−C bond cleavage of…”
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Substrate Specificity, Substrate Channeling, and Allostery in BphJ: An Acylating Aldehyde Dehydrogenase Associated with the Pyruvate Aldolase BphI by Baker, Perrin, Carere, Jason, Seah, Stephen Y. K

“…BphJ, a nonphosphorylating acylating aldehyde dehydrogenase, catalyzes the conversion of aldehydes to form acyl-coenzyme A in the presence of NAD+ and coenzyme…”
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