Search Results - "Carel, J C"

Child Health, Developmental Plasticity, and Epigenetic Programming by Hochberg, Z, Feil, R, Constancia, M, Fraga, M, Junien, C, Carel, J.-C, Boileau, P, Le Bouc, Y, Deal, C. L, Lillycrop, K, Scharfmann, R, Sheppard, A, Skinner, M, Szyf, M, Waterland, R. A, Waxman, D. J, Whitelaw, E, Ong, K, Albertsson-Wikland, K

“…Plasticity in developmental programming has evolved to provide the best chances of survival and reproductive success to the organism under changing…”
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Conditional and Specific NF-κB Blockade Protects Pancreatic Beta Cells from Diabetogenic Agents by Eldor, R., Yeffet, A., Baum, K., Doviner, V., Amar, D., Ben-Neriah, Y., Christofori, G., Peled, A., Carell, J. C., Boitard, C., Klein, T., Serup, P., Eizirik, D. L., Melloul, D.

“…Type 1 diabetes is characterized by the infiltration of inflammatory cells into pancreatic islets of Langerhans, followed by the selective and progressive…”
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Phenotypic Homogeneity and Genotypic Variability in a Large Series of Congenital Isolated ACTH-Deficiency Patients with TPIT Gene Mutations by Couture, C, Saveanu, A, Barlier, A, Carel, J. C, Fassnacht, M, Flück, C. E, Houang, M, Maes, M, Phan-Hug, F, Enjalbert, A, Drouin, J, Brue, T, Vallette, S

“…Context: Congenital isolated ACTH deficiency (IAD) is a rare disease characterized by low plasma ACTH and cortisol levels and preservation of all other…”
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Continuous subcutaneous insulin infusion allows tolerance induction and diabetes treatment in a type 1 diabetic child with insulin allergy by Hasselmann, C, Pecquet, C, Bismuth, E, Raverdy, C, Sola-Gazagnes, A, Lobut, J.-B, Carel, J.-C, Tubiana-Rufi, N

“…Abstract Aim Insulin allergy is a rare but serious and challenging condition in patients with type 1 diabetes (T1D). This is a case report of an 8-year-old boy…”
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Growth hormone treatment before the age of 4 years prevents short stature in young girls with Turner syndrome by Linglart, A, Cabrol, S, Berlier, P, Stuckens, C, Wagner, K, de Kerdanet, M, Limoni, C, Carel, J-C, Chaussain, J-L

“…ObjectiveAdult height deficit seen in Turner syndrome (TS) originates, in part, from growth retardation in utero and throughout the first 3 years of life…”
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Medullary thyroid carcinoma identified within the first year of life in children with hereditary multiple endocrine neoplasia type 2A (codon 634) and 2B by Zenaty, D, Aigrain, Y, Peuchmaur, M, Philippe-Chomette, P, Baumann, C, Cornelis, F, Hugot, J P, Chevenne, D, Barbu, V, Guillausseau, P J, Schlumberger, M, Carel, J C, Travagli, J P, Léger, J

“…ContextEarly prophylactic thyroidectomy in patients with multiple endocrine neoplasia (MEN) type 2 offers the best chance for a normal life…”
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Leydig-Cell Tumors Caused by an Activating Mutation of the Gene Encoding the Luteinizing Hormone Receptor by Liu, Guoquan, Duranteau, Lise, Carel, Jean-Claude, Monroe, Jason, Doyle, Daniel A, Shenker, Andrew

“…The receptor for luteinizing hormone and chorionic gonadotropin plays a major part in normal and abnormal reproductive function. 1 – 4 In males, activation of…”
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Risk of autoimmune diabetes in APECED: association with short alleles of the 5′insulin VNTR by Paquette, J, Varin, D S E, Hamelin, C E, Hallgren, Å, Kämpe, O, Carel, J-C, Perheentupa, J, Deal, C L

“…Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare autoimmune disease causing a wide spectrum of autoimmune dysfunction…”
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Soluble leptin receptor in serum of subjects with complete resistance to leptin: relation to fat mass by LAHLOU, N, CLEMENT, K, GUY-GRAND, B, CAREL, J.-C, VAISSE, C, LOTTON, C, LE BIHAN, Y, BASDEVANT, A, LEBOUC, Y, FROGUEL, P, ROGER, M

“…Soluble leptin receptor in serum of subjects with complete resistance to leptin: relation to fat mass. N Lahlou , K Clement , J C Carel , C Vaisse , C Lotton ,…”
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Near normalization of final height with adapted doses of growth hormone in Turner's syndrome by CAREL, J.-C, MATHIVON, L, GENDREL, C, DUCRET, J.-P, CHAUSSAIN, J.-L

“…An adapted GH dose regimen was evaluated in 14 untreated patients with Turner's syndrome. The initial GH dose (0.7 U/kg.BW) was increased by 0.7 U/kg.BW, up to…”
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Breast Inflammatory Gigantomastia in a Context of Immune-Mediated Diseases by Touraine, P., Youssef, N., Alyanakian, M. A., Lechat, X., Balleyguier, C., Duflos, C., Dib, A., May, A., Carel, J. C., Laborde, K., Sigal-Zafrani, B., Goffin, V., Eymard, B., Boitard, C., Brousse, N., Kuttenn, F.

“…Context: Localized breast lesions have been described in lupic or diabetic patients. However, the description of breast gigantomastia in women presenting with…”
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Novel mutations in the thiazide-sensitive NaCl cotransporter gene in patients with Gitelman syndrome with predominant localization to the C-terminal domain by Lemmink, Henny H., Knoers, Nine V.A.M., Károlyi, Lothar, van Dijk, Henk, Niaudet, Patrick, Antignac, Corinne, Guay-Woodford, Lisa M., Goodyer, Paul R., Carel, Jean-Claude, Hermes, Ad, Seyberth, Hansjörg W., Monnens, Leo A.H., van den Heuvel, Lambert P.W.J.

“…Novel mutations in the thiazide-sensitive NaCl cotransporter gene in patients with Gitelman syndrome. Gitelman syndrome (familial hypokalemia-hypomagnesemia…”
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Effect of gonadotropin-releasing hormone agonist treatment in boys with central precocious puberty: final height results by Mul, D, Bertelloni, S, Carel, J C, Saggese, G, Chaussain, J L, Oostdijk, W

“…The small number of boys present in most studies on final height (FH) after gonadotropin-releasing hormone agonist (GnRHa) treatment for central precocious…”
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Four families with loss of function mutations of the thyrotropin receptor by DE ROUX, N, MISRAHI, M, MILGROM, E, BRAUNER, R, HOUANG, M, CAREL, J. C, GRANIER, M, LE BOUC, Y, GHINEA, N, BOUMEDIENNE, A, TOUBLANC, J. E

“…We observed four families with loss of function mutations of the TSH receptor gene. One patient had a homozygous Pro162 Ala substitution. The three other were…”
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Pharmacokinetics and pharmacodynamics of GnRH agonists: clinical implications in pediatrics by Lahlou, N, Carel, J C, Chaussain, J L, Roger, M

“…Since 1981, GnRH agonist administration has been the treatment of choice for central precocious puberty. Continuous administration of the agonist, instead of…”
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X chromosome gene dosage as a determinant of congenital malformations and of age-related comorbidity risk in patients with Turner syndrome, from childhood to early adulthood by Fiot, Elodie, Zénaty, Delphine, Boizeau, Priscilla, Haignere, Jérémie, Dos Santos, Sophie, Léger, Juliane

“…Objective Turner Syndrome is associated with several phenotypic conditions associated with a higher risk of subsequent comorbidity. We aimed to evaluate the…”
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Low dose linomide in Type I juvenile diabetes of recent onset : a randomised placebo-controlled double blind trial by COUTANT, R, LANDAIS, P, ROSILIO, M, JOHNSEN, C, LAHLOU, N, CHATELAIN, P, CAREL, J. C, LUDVIGSSON, J, BOITARD, C, BOUGNERES, P. F

“…The quinoline-3-carboxamide, linomide, protects non-obese diabetic mice from diabetes. The effects of linomide on insulin needs and beta cell function were…”
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Lack of effect of GnRH agonists on final height in girls with advanced puberty : A randomized long-term pilot study by BOUVATTIER, C, COSTE, J, RODRIGUE, D, TEINTURIER, C, CAREL, J. C, CHAUSSAIN, J. L, BOUGNERES, P. F

“…GnRH agonists improve final height in girls with "true" precocious puberty. To test if a comparable effect can be obtained in older girls, we performed a…”
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Long-Term Mortality and Causes of Death in Isolated GHD, ISS, and SGA Patients Treated with Recombinant Growth Hormone during Childhood in Belgium, The Netherlands, and Sweden: Preliminary Report of 3 Countries Participating in the EU SAGhE Study by Sävendahl, Lars, Maes, Marc, Albertsson-Wikland, Kerstin, Borgström, Birgit, Carel, Jean-Claude, Henrard, Séverine, Speybroeck, Niko, Thomas, Muriel, Zandwijken, Gladys, Hokken-Koelega, Anita

“…Context: The long-term mortality in adults treated with recombinant GH during childhood has been poorly investigated. Recently released data from the French…”
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Zinc transporter (ZnT)8186–194 is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients by Scotto, M., Afonso, G., Larger, E., Raverdy, C., Lemonnier, F. A., Carel, J. C., Dubois-Laforgue, D., Baz, B., Levy, D., Gautier, J. F., Launay, O., Bruno, G., Boitard, C., Sechi, L. A., Hutton, J. C., Davidson, H. W., Mallone, R.

“…Aims/hypothesis Anti-zinc transporter (ZnT)8 autoantibodies are commonly detected in type 1 diabetic patients. We hypothesised that ZnT8 is also recognised by…”
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