Search Results - "Care, M"

Everolimus long-term safety and efficacy in subependymal giant cell astrocytoma by KRUEGER, Darcy A, CARE, Marguerite M, AGRICOLA, Karen, TUDOR, Cindy, MAYS, Maxwell, FRANZ, David Neal

“…To report long-term efficacy and safety data for everolimus for the treatment of subependymal giant cell astrocytoma (SEGA) in patients with tuberous sclerosis…”
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Everolimus for subependymal giant cell astrocytoma: 5-year final analysis by Franz, David N., Agricola, Karen, Mays, Maxwell, Tudor, Cindy, Care, Marguerite M., Holland-Bouley, Katherine, Berkowitz, Noah, Miao, Sara, Peyrard, Séverine, Krueger, Darcy A.

“…Objective To analyze the cumulative efficacy and safety of everolimus in treating subependymal giant cell astrocytomas (SEGA) associated with tuberous…”
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Do the Trajectories of Dyspnea Differ in Prevalence and Intensity By Diagnosis at the End of Life? A Consecutive Cohort Study by Currow, David C., BMed, MPH, FRACP, Smith, Joanna, BPsych, Davidson, Patricia M., BA, MEd, PhD, Newton, Phillip J., BN (Hons), PhD, Agar, Meera R., MBBS (Hons), M Pall Care, FRACP, FAChPM, Abernethy, Amy P., MD

“…Abstract Context Breathlessness reportedly worsens as death approaches for many people, but the differences in intensity and time course between underlying…”
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Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding by Ptasinska, A, Assi, S A, Mannari, D, James, S R, Williamson, D, Dunne, J, Hoogenkamp, M, Wu, M, Care, M, McNeill, H, Cauchy, P, Cullen, M, Tooze, R M, Tenen, D G, Young, B D, Cockerill, P N, Westhead, D R, Heidenreich, O, Bonifer, C

“…The t(8;21) translocation fuses the DNA-binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein…”
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Prevalence of subdural collections in children with macrocrania by Greiner, M V, Richards, T J, Care, M M, Leach, J L

“…The relationship between enlarged subarachnoid spaces and subdural collections is poorly understood and creates challenges for clinicians investigating the…”
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S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells by Vrzalikova, K, Ibrahim, M, Vockerodt, M, Perry, T, Margielewska, S, Lupino, L, Nagy, E, Soilleux, E, Liebelt, D, Hollows, R, Last, A, Reynolds, G, Abdullah, M, Curley, H, Care, M, Krappmann, D, Tooze, R, Allegood, J, Spiegel, S, Wei, W, Woodman, C B J, Murray, P G

“…The Hodgkin/Reed–Sternberg cells of classical Hodgkin lymphoma (HL) are characterised by the aberrant activation of multiple signalling pathways. Here we show…”
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An ultra-deep sequencing strategy to detect sub-clonal TP53 mutations in presentation chronic lymphocytic leukaemia cases using multiple polymerases by Worrillow, L, Baskaran, P, Care, M A, Varghese, A, Munir, T, Evans, P A, O'Connor, S J, Rawstron, A, Hazelwood, L, Tooze, R M, Hillmen, P, Newton, D J

“…Chronic lymphocytic leukaemia (CLL) is the most common clonal B-cell disorder characterized by clonal diversity, a relapsing and remitting course, and in its…”
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Application of Hereditary Renal Cell Carcinoma Risk Criteria to a Large Prospective Database by Kushnir, I., Kirk, L., Mallick, R., Kim, R.H., Graham, G.E., Breau, R.H., Lattouf, J.-B., Violette, P.D., Pautler, S.E., Care, M., Kapoor, A., Jewett, M.A.S., Wood, L., Tanguay, S., Heng, D.Y.C., Basappa, N.S., So, A., Pouliot, F., Reaume, N.M.

“…To evaluate the clinical impact of the Canadian criteria for identifying patients and families at risk for hereditary renal cell carcinoma (RCC). The Canadian…”
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Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis by Krueger, Darcy A, Care, Marguerite M, Holland, Katherine, Agricola, Karen, Tudor, Cynthia, Mangeshkar, Prajakta, Wilson, Kimberly A, Byars, Anna, Sahmoud, Tarek, Franz, David Neal

“…Neurosurgical resection is standard for subependymal giant-cell astrocytomas (SEGAs) in tuberous sclerosis. Treatment with everolimus, which inhibits the…”
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In silico multi-scale model of transport and dynamic seeding in a bone tissue engineering perfusion bioreactor by Spencer, T.J., Hidalgo-Bastida, L.A., Cartmell, S.H., Halliday, I., Care, C.M.

“…Computer simulations can potentially be used to design, predict, and inform properties for tissue engineering perfusion bioreactors. In this work, we…”
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Process and Product in Computer-Based Assessments: Clearing the Ground for a Holistic Validity Framework by Zumbo, Bruno D., Maddox, Bryan, Care, Naomi M.

“…There is no consensus among assessment researchers about many of the central problems of response process data, including what is it and what is it comprised…”
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A category‐free approach to prognostic modelling in aggressive non‐Hodgkin B cell lymphomas based on large patient databases by Burton, C., Sha, C., Barrans, S., Jack, A., Painter, D., Smith, A., Roman, E., Crouch, S., Care, M., Tooze, R., Westhead, D.

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Macrocephaly and subdural collections by Caré, Marguerite M.

“…Enlarged subarachnoid spaces are a common finding in infants and young children imaged for macrocephaly or an enlarging head circumference, and benign…”
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Combining the interactome and deleterious SNP predictions to improve disease gene identification by Care, M.A, Bradford, J.R, Needham, C.J, Bulpitt, A.J, Westhead, D.R

“…A method has been developed for the prediction of proteins involved in genetic disorders. This involved combining deleterious SNP prediction with a system…”
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Molecular analysis of primary cutaneous diffuse large B‐cell lymphoma, leg type by Goodlad, J.R., Hoppe, S., Ahmed, S., Barrans, S.L., Painter, D., Care, M., Taylor, J., Evans, P., Bentley, M., Tooze, R.M., Smith, A., Crouch, S., Roman, E., Westhead, D.R., Burton, C.

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Incidental Thalamic Lesions Identified on Brain MRI in Pediatric and Young Adult Patients: Imaging Features and Natural History by Alves, Vinicius de Padua V, Care, Marguerite M, Leach, James L

“…Nonspecific, localized thalamic signal abnormalities of uncertain significance are occasionally found on pediatric brain MR imaging. The goal of this study is…”
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Efficacy and Safety of Alemtuzumab in Patients of African Descent with Relapsing-Remitting Multiple Sclerosis: 8-Year Follow-up of CARE-MS I and II (TOPAZ Study) by Okai, Annette F., Amezcua, Lilyana, Berkovich, Regina R., Chinea, Angel R., Edwards, Keith R., Steingo, Brian, Walker, Aljoeson, Jacobs, Alan K., Daizadeh, Nadia, Williams, Mitzi J.

“…Introduction Multiple sclerosis (MS) patients of African descent have increased risk for disease progression and may be less responsive to disease-modifying…”
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An accurate and versatile lattice closure scheme for lattice Boltzmann equation fluids under external forces by Hollis, A.P., Halliday, I., Care, C.M.

“…We derive and demonstrate a practical, analytic, versatile and accurate algorithm designed to impose Dirichlet boundary conditions (specified boundary…”
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Lattice Boltzmann algorithm for continuum multicomponent flow by Halliday, I, Hollis, A P, Care, C M

“…We present a multicomponent lattice Boltzmann simulation for continuum fluid mechanics, paying particular attention to the component segregation part of the…”
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Parenchymal Insults in Abuse-A Potential Key to Diagnosis by Caré, Marguerite M

“…Subdural hemorrhage is a key imaging finding in cases of abusive head trauma and one that many radiologists and radiology trainees become familiar with during…”
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