Search Results - "Cardoso, Fernanda"

Multi-targeting sodium and calcium channels using venom peptides for the treatment of complex ion channels-related diseases by Cardoso, Fernanda C

“…[Display omitted] Venom peptides are amongst the most exquisite group of bioactive molecules able to alter the normal physiology of organisms. These bioactive…”
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Sodium channels and pain: from toxins to therapies by Cardoso, Fernanda C, Lewis, Richard J

“…Voltage‐gated sodium channels (NaV channels) are essential for the initiation and propagation of action potentials that critically influence our ability to…”
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Spider Knottin Pharmacology at Voltage-Gated Sodium Channels and Their Potential to Modulate Pain Pathways by Dongol, Yashad, Cardoso, Fernanda Caldas, Lewis, Richard J

“…Voltage-gated sodium channels (Na s) are a key determinant of neuronal signalling. Neurotoxins from diverse taxa that selectively activate or inhibit Na…”
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Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain by Hasan, Md Mahadhi, Ragnarsson, Lotten, Cardoso, Fernanda C, Lewis, Richard J

“…Chemical transfection is broadly used to transiently transfect mammalian cells, although often associated with cellular stress and membrane instability, which…”
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Structure-Function and Therapeutic Potential of Spider Venom-Derived Cysteine Knot Peptides Targeting Sodium Channels by Cardoso, Fernanda C, Lewis, Richard J

“…Spider venom-derived cysteine knot peptides are a mega-diverse class of molecules that exhibit unique pharmacological properties to modulate key membrane…”
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The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant by Rahnama, Sassan, Deuis, Jennifer R, Cardoso, Fernanda C, Ramanujam, Venkatraman, Lewis, Richard J, Rash, Lachlan D, King, Glenn F, Vetter, Irina, Mobli, Mehdi

“…Venom-derived peptides have attracted much attention as potential lead molecules for pharmaceutical development. A well-known example is Huwentoxin-IV…”
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Influence of reaction parameters in the polymerization between genipin and chitosan for enzyme immobilization by Flores, Elí Emanuel Esparza, Cardoso, Fernanda Dias, Siqueira, Larissa Bertoldo, Ricardi, Natália Carminatti, Costa, Tania Haas, Rodrigues, Rafael C., Klein, Manuela Poletto, Hertz, Plinho Francisco

“…[Display omitted] •An effective method for chitosan beads activation using genipin was developed.•β-galactosidase was immobilized presenting high thermal and…”
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A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome by Cardoso, Fernanda C., Castro, Joel, Grundy, Luke, Schober, Gudrun, Garcia-Caraballo, Sonia, Zhao, Tianjiao, Herzig, Volker, King, Glenn F., Brierley, Stuart M., Lewis, Richard J.

“…Chronic pain is a serious debilitating condition that affects ∼20% of the world's population. Currently available drugs fail to produce effective pain relief…”
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Phylogeny, envenomation syndrome, and membrane permeabilising venom produced by Australia’s electric caterpillar Comana monomorpha by Goudarzi, Mohaddeseh H., Robinson, Samuel D., Cardoso, Fernanda C., Mitchell, Michela L., Cook, Lyn G., King, Glenn F., Walker, Andrew A.

“…Zygaenoidea is a superfamily of lepidopterans containing many venomous species, including the Limacodidae (nettle caterpillars) and Megalopygidae (asp…”
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The Deadly Toxin Arsenal of the Tree-Dwelling Australian Funnel-Web Spiders by Cardoso, Fernanda C., Pineda, Sandy S., Herzig, Volker, Sunagar, Kartik, Shaikh, Naeem Yusuf, Jin, Ai-Hua, King, Glenn F., Alewood, Paul F., Lewis, Richard J., Dutertre, Sébastien

“…Australian funnel-web spiders are amongst the most dangerous venomous animals. Their venoms induce potentially deadly symptoms, including hyper- and…”
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Landscape conservation as a strategy for recovering biodiversity: Lessons from a long‐term program of pasture restoration in the southern Atlantic Forest by Cardoso, Fernanda C. G., Capellesso, Elivane S., Britez, Ricardo Miranda, Inague, Gabriel, Marques, Marcia C. M.

“…Although ecological restoration has entered the global agenda to reverse different anthropogenic disturbances, we still know little about how this solution…”
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Editorial: Venom peptides: A rich combinatorial library for drug development, volume II by Servent, Denis, Cardoso, Fernanda C, De Lima, Maria Elena

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An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas by Gaze, Soraya, Driguez, Patrick, Pearson, Mark S, Mendes, Tiago, Doolan, Denise L, Trieu, Angela, McManus, Donald P, Gobert, Geoffrey N, Periago, Maria Victoria, Correa Oliveira, Rodrigo, Cardoso, Fernanda C, Oliveira, Guilherme, Nakajima, Rie, Jasinskas, Al, Hung, Chris, Liang, Li, Pablo, Jozelyn, Bethony, Jeffrey M, Felgner, Philip L, Loukas, Alex

“…Schistosomiasis is a neglected tropical disease that is responsible for almost 300,000 deaths annually. Mass drug administration (MDA) is used worldwide for…”
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Obstetric violence and LGBTQIA+phobia: interlaced oppressions and violations by Goncalves Cardoso, Priscila Fernanda, Shimizu, Mariana Arissa

“…Abstract The cisheteropatriarchal capitalist system has developed by class, racial and sexual oppression and exploitation in establishing unequal, hierarchical…”
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The T-type calcium channel Ca V 3.2 regulates bladder afferent responses to mechanical stimuli by Grundy, Luke, Tay, Cindy, Christie, Stewart, Harrington, Andrea M., Castro, Joel, Cardoso, Fernanda C., Lewis, Richard J., Zagorodnyuk, Vladimir, Brierley, Stuart M.

“…The bladder wall is innervated by a complex network of afferent nerves that detect bladder stretch during filling. Sensory signals, generated in response to…”
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Structure-function and rational design of a spider toxin Ssp1a at human voltage-gated sodium channel subtypes by Dongol, Yashad, Wilson, David T., Daly, Norelle L., Cardoso, Fernanda C., Lewis, Richard J.

“…The structure-function and optimization studies of Na V -inhibiting spider toxins have focused on developing selective inhibitors for peripheral pain-sensing…”
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Differences in cycle threshold values in RT-PCR tests between children and adults with monkeypox: Results from a community-based cross-sectional study by Martins-Filho, Paulo Ricardo, Menezes Dorea, Fernanda Cardoso, Brito Bezerra, Gabriela Vasconcelos, dos Santos, Cliomar Alves

“…Recently, we have demonstrated that skin samples had a higher RT-PCR positivity rate and lower cycle threshold (Ct) values compared to other biological…”
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Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae) by Walker, Andrew A, Robinson, Samuel D, Merritt, David J, Cardoso, Fernanda C, Goudarzi, Mohaddeseh Hedayati, Mercedes, Raine S, Eagles, David A, Cooper, Paul, Zdenek, Christina N, Fry, Bryan G, Hall, Donald W, Vetter, Irina, King, Glenn F

“…Larvae of the genus (Lepidoptera: Zygaenoidea: Megalopygidae), known as asp or puss caterpillars, produce defensive venoms that cause severe pain. Here, we…”
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Editorial: Venom Peptides: A Rich Combinatorial Library for Drug Development by Cardoso, Fernanda C, Servent, Denis, de Lima, Maria Elena

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Schistosoma mansoni tegument protein Sm29 is able to induce a Th1-type of immune response and protection against parasite infection by Cardoso, Fernanda C, Macedo, Gilson C, Gava, Elisandra, Kitten, Gregory T, Mati, Vitor L, de Melo, Alan L, Caliari, Marcelo V, Almeida, Giulliana T, Venancio, Thiago M, Verjovski-Almeida, Sergio, Oliveira, Sergio C

“…Schistosomiasis continues to be a significant public health problem. This disease affects 200 million people worldwide and almost 800 million people are at…”
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