Search Results - "Cardoso, Cristina R."

Enrichment of regulatory T cells in invasive breast tumor correlates with the upregulation of IL‐17A expression and invasiveness of the tumor by Benevides, Luciana, Cardoso, Cristina R. B., Tiezzi, Daniel G., Marana, Heitor R. C., Andrade, Jurandyr M., Silva, João S.

“…Breast cancer is a leading cause of neoplasia‐associated death in women worldwide. Regulatory T (Treg) and Th17 cells are enriched within some tumors, but the…”
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Selective Suppression of Cellular Immunity and Increased Cytotoxicity in Skin Lesions of Disseminated Leishmaniasis Uncovered by Transcriptome-Wide Analysis by Ramos, Pablo Ivan Pereira, Cristal, Juqueline Rocha, Khouri, Ricardo, Boaventura, Viviane, Azevedo, Lucas Gentil, Correia, Thaizza Cavalcante, Sharma, Rohit, Cardoso, Cristina R. de Barros, Pinzan, Camila Figueiredo, de Noronha, Almério Libório Lopes, Van Weyenbergh, Johan, Queiroz, Artur Trancoso Lopo de, de Oliveira, Camila I., Barral-Netto, Manoel, Barral, Aldina

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Chlorhexidine-induced apoptosis or necrosis in L929 fibroblasts: A role for endoplasmic reticulum stress by Faria, Gisele, Cardoso, Cristina R.B., Larson, Roy E., Silva, João S., Rossi, Marcos A.

“…Chlorhexidine (CHX), widely used as antiseptic and therapeutic agent in medicine and dentistry, has a toxic effect both in vivo and in vitro. The intrinsic…”
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The essential role of IFN-γ in the control of lethal Aggregatibacter actinomycetemcomitans infection in mice by Garlet, Gustavo P., Cardoso, Cristina R.B., Campanelli, Ana P., Garlet, Thiago P., Avila-Campos, Mario J., Cunha, Fernando Q., Silva, João S.

“…Inflammatory immune reactions in response to periodontopathogens trigger periodontal destruction, but their role to protect the host against infection remains…”
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The Severity of COVID-19 Affects the Plasma Soluble Levels of the Immune Checkpoint HLA-G Molecule by Cordeiro, Jéssica F. C., Fernandes, Talita M., Toro, Diana M., da Silva-Neto, Pedro V., Pimentel, Vinícius E., Pérez, Malena M., de Carvalho, Jonatan C. S., Fraga-Silva, Thais F. C., Oliveira, Camilla N. S., Argolo, Jamille G. M., Degiovani, Augusto M., Ostini, Fátima M., Puginna, Enrico F., da Silva, João S., Santos, Isabel K. F. M., Bonato, Vânia L. D., Cardoso, Cristina R. B., Dias-Baruffi, Marcelo, Faccioli, Lúcia H., Donadi, Eduardo A., Sorgi, Carlos A., Fernandes, Ana P. M.

“…The non-classical histocompatibility antigen G (HLA-G) is an immune checkpoint molecule that has been implicated in viral disorders. We evaluated the plasma…”
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The broad effects of the functional IL-10 promoter-592 polymorphism: modulation of IL-10, TIMP-3, and OPG expression and their association with periodontal disease outcome by Marcela Claudino, Ana Paula F. Trombone, Cristina R. Cardoso, Samuel B. Ferreira, Jr, Walter Martins, Jr, Gerson F. Assis, Carlos F. Santos, Paula C. Trevilatto, Ana Paula Campanelli, João S. Silva, Gustavo P. Garlet

“…Periodontal diseases are infectious diseases, in which periodontopathogens trigger chronic inflammatory and immune responses that lead to tissue destruction…”
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AeMOPE-1, a Novel Salivary Peptide From Aedes aegypti , Selectively Modulates Activation of Murine Macrophages and Ameliorates Experimental Colitis by Lara, Priscila G, Esteves, Eliane, Sales-Campos, Helioswilton, Assis, Josiane B, Henrique, Maressa O, Barros, Michele S, Neto, Leila S, Silva, Pedro I, Martins, Joilson O, Cardoso, Cristina R B, Ribeiro, José M C, Sá-Nunes, Anderson

“…The sialotranscriptomes of revealed a transcript overexpressed in female salivary glands that codes a mature 7.8 kDa peptide. The peptide, specific to the…”
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Endothelinergic Contractile Hyperreactivity in Rat Contralateral Carotid to Balloon Injury: Integrated Role for ETB Receptors and Superoxide Anion by Moreira, Josimar D., Cardoso, Cristina Ribeiro Barros, do Vale, Bruno N., Gomes, Mayara Santos, Gimenes, Lilian R., Pernomian, Larissa, de Oliveira, Ana M.

“…Temporal consequences of neurocompensation to balloon injury on endothelinergic functionality in rat contralateral carotid were evaluated. Rats underwent…”
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Toxoplasma gondii soluble tachyzoite antigen triggers protective mechanisms against fatal intestinal pathology in oral infection of C57BL/6 mice by Benevides, Luciana, Cardoso, Cristina R, Milanezi, Cristiane M, Castro-Filice, Letícia S, Barenco, Paulo V C, Sousa, Romulo O, Rodrigues, Rosangela M, Mineo, José R, Silva, João S, Silva, Neide M

“…Toxoplasma gondii induces a potent IL-12 response early in infection that results in IFN-γ-dependent control of parasite growth. It was previously shown that…”
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Interleukin-1β (IL-1β) Single-Nucleotide Polymorphism at Position 3954 and Red Complex Periodontopathogens Independently and Additively Modulate the Levels of IL-1β in Diseased Periodontal Tissues by Ferreira, Samuel B. Jr, Trombone, Ana Paula F, Repeke, Carlos E, Cardoso, Cristina R, Martins, Walter Jr, Santos, Carlos F, Trevilatto, Paula Cristina, Ávila-Campos, Mario J, Campanelli, Ana Paula, Silva, João S, Garlet, Gustavo P

“…Inflammatory cytokines such as interleukin-1β (IL-1β) are involved in the pathogenesis of periodontal diseases. A high individual variation in the levels of…”
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IL-4 regulates susceptibility to intestinal inflammation in murine food allergy by Cardoso, Cristina R, Provinciatto, Pauline R, Godoi, Dannielle F, Ferreira, Beatriz R, Teixeira, Gerlinde, Rossi, Marcos A, Cunha, Fernando Q, Silva, João S

“…Allergies involve a state of immediate hypersensitivity to antigens, including food proteins. The mechanism underlying the initiation and development of…”
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Down-regulation of expression of osteoblast and osteocyte markers in periodontal tissues associated with the spontaneous alveolar bone loss of interleukin-10 knockout mice by Claudino, Marcela, Garlet, Thiago P., Cardoso, Cristina R. B., De Assis, Gerson F., Taga, Rumio, Cunha, Fernando Q., Silva, João S., Garlet, Gustavo P.

“…Claudino M, Garlet TP, Cardoso CRB, de Assis GF, Taga R, Cunha FQ, Silva JS, Garlet GP. Down‐regulation of expression of osteoblast and osteocyte markers in…”
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BALB/c mice infected with antimony treatment refractory isolate of Leishmania braziliensis present severe lesions due to IL-4 production by Costa, Diego L, Carregaro, Vanessa, Lima-Júnior, Djalma S, Silva, Neide M, Milanezi, Cristiane M, Cardoso, Cristina R, Giudice, Ângela, de Jesus, Amélia R, Carvalho, Edgar M, Almeida, Roque P, Silva, João S

“…Leishmania braziliensis is the main causative agent of cutaneous leishmaniasis in Brazil. Protection against infection is related to development of Th1…”
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Acetylcholine, Fatty Acids, and Lipid Mediators Are Linked to COVID-19 Severity by Pérez, Malena M., Pimentel, Vinícius E., Fuzo, Carlos A., da Silva-Neto, Pedro V., Toro, Diana M., Fraga-Silva, Thais F. C., Gardinassi, Luiz G., Oliveira, Camilla N. S., Souza, Camila O. S., Torre-Neto, Nicola T., de Carvalho, Jonatan C. S., De Leo, Thais C., Nardini, Viviani, Feitosa, Marley R., Parra, Rogerio S., da Rocha, José J. R., Feres, Omar, Vilar, Fernando C., Gaspar, Gilberto G., Constant, Leticia F., Ostini, Fátima M., Degiovani, Augusto M., Amorim, Alessandro P., Viana, Angelina L., Fernandes, Ana P. M., Maruyama, Sandra R., Russo, Elisa M. S., Santos, Isabel K. F. M., Bonato, Vânia L. D., Cardoso, Cristina R. B., Sorgi, Carlos A., Dias-Baruffi, Marcelo, Faccioli, Lúcia H.

“…Lipid and cholinergic mediators are inflammatory regulators, but their role in the immunopathology of COVID-19 is still unclear. Here, we used human blood and…”
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Regulatory T cells attenuate experimental periodontitis progression in mice by Garlet, Gustavo P., Cardoso, Cristina R., Mariano, Flavia S., Claudino, Marcela, De Assis, Gerson F., Campanelli, Ana P., Ávila-Campos, Mario J., Silva, João S.

“…Garlet GP, Cardoso CR, Mariano FS, Claudino M, de Assis GF, Campanelli AP, Ávila‐Campos MJ, Silva JS. Regulatory T cells attenuate experimental periodontitis…”
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Divergent androgenic modulation of SARS-CoV-2 infection cooperates with dysregulated immune response to dictate worse COVID-19 outcomes in men by Duarte-Silva, Murillo, Oliveira, Camilla N.S., Fuzo, Carlos, Silva-Neto, Pedro V., Toro, Diana M., Pimentel, Vinícius E., Pérez, Malena M., Fraga-Silva, Thais F.C., Carvalho, Jonatan C.S., Neto, Firmino M.S., Júnior, Ronaldo B.M., Arruda, Eurico, Vilar, Fernando C., Degiovani, Augusto M., Ostini, Fátima M., Feitosa, Marley R., Parra, Rogerio S., Gaspar, Gilberto G., Rocha, José J.R., Feres, Omar, Fernandes, Ana P.M., Maruyama, Sandra R., Russo, Elisa M.S., Bonato, Vânia L.D., Santos, Isabel K.F.M., Sorgi, Carlos A., Dias-Baruffi, Marcelo, Faccioli, Lúcia H., Cardoso, Cristina R.B.

“…•Lowering testosterone is a hallmark of the worst COVID-19 prognosis in men.•Reduced testosterone in men with COVID-19 is partially dependent on age and…”
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The turning point of COVID‐19 severity is associated with a unique circulating neutrophil gene signature by Fuzo, Carlos A., Fraga‐Silva, Thais F. C., Maruyama, Sandra R., Bastos, Víctor A. F., Rogerio, Luana A., Takamiya, Nayore T., Silva‐Neto, Pedro V., Pimentel, Vinícius E., Toro, Diana M., Pérez, Malena M., Carvalho, Jonatan C. S., Carmona‐Garcia, Ingryd, Oliveira, Camilla N. S., Degiovani, Augusto M., Ostini, Fátima M., Constant, Leticia F., Amorim, Alessandro P., Vilar, Fernando C., Feitosa, Marley R., Parra, Rogerio S., Rocha, José J. R., Feres, Omar, Gaspar, Gilberto G., Viana, Angelina L., Fernandes, Ana P. M., Santos, Isabel K. F. M., Russo, Elisa M. S., Cardoso, Cristina R. B., Sorgi, Carlos A., Faccioli, Lúcia H., Bonato, Vânia L. D., Dias‐Baruffi, Marcelo

“…COVID‐19 has a broad spectrum of clinical manifestations associated with the host immune response heterogeneity. Despite the advances in COVID‐19 research, it…”
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Cinnamaldehyde modulates host immunoinflammatory responses in rat ligature-induced periodontitis and peripheral blood mononuclear cell models by de Oliveira, Izabel C.V., Galvão-Moreira, Leonardo V., Vilela, Juliana L., Duarte-Silva, Murillo, Aguiar-da-Silva, Lucas D., Pereira, Cesar A.A., Pereira, Domingos M.S., Pinheiro, Aruanã J.M.C.R., Lima-Neto, Lídio G., Fernandes, Elizabeth S., Cardoso, Cristina R.B., Branco-de-Almeida, Luciana S.

“…•Cinnamaldehyde treatment reduced alveolar bone resorption in ligature-induced periodontitis in rats.•Cinnamaldehyde treatment reduced IL-1β, MMP-9 and iNOS…”
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Human mucosal leishmaniasis: Neutrophils infiltrate areas of tissue damage that express high levels of Th17-related cytokines by Boaventura, Viviane S, Santos, Claire S, Cardoso, Cristina R, de Andrade, José, Dos Santos, Washington L.C, Clarêncio, Jorge, Silva, João S, Borges, Valeria M, Barral-Netto, Manoel, Brodskyn, Claudia I, Barral, Aldina

“…Mucosal leishmaniasis (ML) is characterised by severe tissue destruction. Herein, we evaluated the involvement of the IL-17-type response in the inflammatory…”
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Amelioration of experimental colitis after short‐term therapy with glucocorticoid and its relationship to the induction of different regulatory markers by Sales‐Campos, Helioswilton, Souza, Patrícia R., Basso, Paulo J., Nardini, Viviani, Silva, Angelica, Banquieri, Fernanda, Alves, Vanessa B. F., Chica, Javier E. L., Nomizo, Auro, Cardoso, Cristina R. B.

“…Summary The clinical benefits of short‐term therapy with glucocorticoids (GC) in patients with inflammatory bowel disease (IBD) are widely known. However, the…”
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