Search Results - "Cardona, Pere Joan"

Regulatory T Cells in Mycobacterium tuberculosis Infection by Cardona, Paula, Cardona, Pere-Joan

“…Anti-inflammatory regulatory T cells have lately attracted attention as part of the immune response to infection, where they counterbalance the protective but…”
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Foamy macrophages and the progression of the human tuberculosis granuloma by Altare, Frédéric, Allain, Sophie, Cardona, Pere-Joan, Kim, Mi-Jeong, Russell, David G

“…The progression of tuberculosis from a latent, subclinical infection to active disease that culminates in the transmission of infectious bacilli is determined…”
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Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity by Tur, Juan, Pereira-Lopes, Selma, Vico, Tania, Marín, Eros A., Muñoz, Juan P., Hernández-Alvarez, Maribel, Cardona, Pere-Joan, Zorzano, Antonio, Lloberas, Jorge, Celada, Antonio

“…Mitofusin 2 (Mfn2) plays a major role in mitochondrial fusion and in the maintenance of mitochondria-endoplasmic reticulum contact sites. Given that…”
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Characterization of respiratory bacterial co-infection and assessment of empirical antibiotic treatment in patients with COVID-19 at hospital admission by Antuori, Adrián, Giménez, Montserrat, Linares, Georgina, Cardona, Pere-Joan

“…Accurate characterization of respiratory bacterial co-infection is critical for guiding empirical antibiotic treatment for hospitalised patients with…”
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Origin of tuberculosis in the Paleolithic predicts unprecedented population growth and female resistance by Cardona, Pere-Joan, Català, Martí, Prats, Clara

“…Current data estimate the origin of Mycobacterium tuberculosis complex (MtbC) infection around 73,000 years before the common era (BCE), and its evolution to…”
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What We Have Learned and What We Have Missed in Tuberculosis Pathophysiology for a New Vaccine Design: Searching for the "Pink Swan" by Cardona, Pere-Joan

“…This is a call to encourage the search for a new vaccine to stop the progression of infection to tuberculosis (TB) disease. TB is a highly discreet and…”
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Drosophila melanogaster as a model to study innate immune memory by Arch, Marta, Vidal, Maria, Koiffman, Romina, Melkie, Solomon Tibebu, Cardona, Pere-Joan

“…Over the last decades, research regarding innate immune responses has gained increasing importance. A growing body of evidence supports the notion that the…”
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Experimental animal modelling for TB vaccine development by Cardona, Pere-Joan, Williams, Ann

“…Highlights • Vaccines are screened in multiple animal models and each has merits. • Models which better reflect the human pathology spectrum should be included…”
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Empirical model for short-time prediction of COVID-19 spreading by Català, Martí, Alonso, Sergio, Alvarez-Lacalle, Enrique, López, Daniel, Cardona, Pere-Joan, Prats, Clara

“…The appearance and fast spreading of Covid-19 took the international community by surprise. Collaboration between researchers, public health workers, and…”
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Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers by Català, Martí, Pino, David, Marchena, Miquel, Palacios, Pablo, Urdiales, Tomás, Cardona, Pere-Joan, Alonso, Sergio, López-Codina, David, Prats, Clara, Alvarez-Lacalle, Enrique

“…Policymakers need clear, fast assessment of the real spread of the COVID-19 epidemic in each of their respective countries. Standard measures of the situation…”
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Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence by Peyron, Pascale, Vaubourgeix, Julien, Poquet, Yannick, Levillain, Florence, Botanch, Catherine, Bardou, Fabienne, Daffé, Mamadou, Emile, Jean-François, Marchou, Bruno, Cardona, Pere-Joan, de Chastellier, Chantal, Altare, Frédéric

“…Tuberculosis (TB) is characterized by a tight interplay between Mycobacterium tuberculosis and host cells within granulomas. These cellular aggregates restrict…”
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Safety, tolerability, and immunogenicity of the novel antituberculous vaccine RUTI: randomized, placebo-controlled phase II clinical trial in patients with latent tuberculosis infection by Nell, Andre S, D'lom, Eva, Bouic, Patrick, Sabaté, Montserrat, Bosser, Ramon, Picas, Jordi, Amat, Mercè, Churchyard, Gavin, Cardona, Pere-Joan

“…To evaluate the safety, tolerability and immunogenicity of three different doses (5, 25 and 50 µg) of the novel antituberculous vaccine RUTI compared to…”
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Editorial: Immuno-diagnosis of active tuberculosis; are we making progress? by Mayanja-Kizza, Harriet, Cardona, Pere-Joan, Chegou, Novel N

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Predicting the artificial immunity induced by RUTI® vaccine against tuberculosis using universal immune system simulator (UISS) by Pennisi, Marzio, Russo, Giulia, Sgroi, Giuseppe, Bonaccorso, Angela, Parasiliti Palumbo, Giuseppe Alessandro, Fichera, Epifanio, Mitra, Dipendra Kumar, Walker, Kenneth B, Cardona, Pere-Joan, Amat, Merce, Viceconti, Marco, Pappalardo, Francesco

“…Tuberculosis (TB) represents a worldwide cause of mortality (it infects one third of the world's population) affecting mostly developing countries, including…”
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A reaction-diffusion model to understand granulomas formation inside secondary lobule during tuberculosis infection by Català, Martí, Prats, Clara, López, Daniel, Cardona, Pere-Joan, Alonso, Sergio

“…Mycobacterium tuberculosis (Mtb) is the causative agent for tuberculosis, the most extended infectious disease around the world. When Mtb enters inside the…”
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Moving forward through the in silico modeling of tuberculosis: a further step with UISS-TB by Russo, Giulia, Sgroi, Giuseppe, Parasiliti Palumbo, Giuseppe Alessandro, Pennisi, Marzio, Juarez, Miguel A, Cardona, Pere-Joan, Motta, Santo, Walker, Kenneth B, Fichera, Epifanio, Viceconti, Marco, Pappalardo, Francesco

“…In 2018, about 10 million people were found infected by tuberculosis, with approximately 1.2 million deaths worldwide. Despite these numbers have been…”
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Reactivation or Reinfection in Adult Tuberculosis: Is That the Question? by Cardona, Pere-Joan

“…Abstract Looking at the chapter on “natural history” in any tuberculosis (TB) reference book, there is a kind of certainty regarding TB in adults. That is the…”
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Mouse Models for Mycobacterium tuberculosis Pathogenesis: Show and Do Not Tell by Soldevilla, Pablo, Vilaplana, Cristina, Cardona, Pere-Joan

“…Science has been taking profit from animal models since the first translational experiments back in ancient Greece. From there, and across all history, several…”
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Influence of Gut Microbiota on Progression to Tuberculosis Generated by High Fat Diet-Induced Obesity in C3HeB/FeJ Mice by Arias, Lilibeth, Goig, Galo Adrián, Cardona, Paula, Torres-Puente, Manuela, Díaz, Jorge, Rosales, Yaiza, Garcia, Eric, Tapia, Gustavo, Comas, Iñaki, Vilaplana, Cristina, Cardona, Pere-Joan

“…The administration of a high fat content diet is an accelerating factor for metabolic syndrome, impaired glucose tolerance, and early type 2 diabetes. The…”
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A Beneficial Effect of Low-Dose Aspirin in a Murine Model of Active Tuberculosis by Kroesen, Vera Marie, Rodríguez-Martínez, Paula, García, Eric, Rosales, Yaiza, Díaz, Jorge, Martín-Céspedes, Montse, Tapia, Gustavo, Sarrias, Maria Rosa, Cardona, Pere-Joan, Vilaplana, Cristina

“…An excessive, non-productive host-immune response is detrimental in active, chronic tuberculosis (TB) disease as it typically leads to tissue damage. Given…”
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