Search Results - "Carding, SR"

Inflammatory bowel disease: cause and immunobiology by Baumgart, Daniel C, Dr, Carding, Simon R, Prof

“…Summary Crohn's disease and ulcerative colitis are idiopathic inflammatory bowel disorders. In this paper, we discuss how environmental factors (eg, geography,…”
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gamma delta T cells: Functional plasticity and heterogeneity by Carding, SR, Egan, P J

“…gamma delta T cells are a unique and highly conserved lineage of T cells. Differences in their tissue distribution and the types and mode of antigen…”
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Downmodulation of the Inflammatory Response to Bacterial Infection by gamma delta T Cells Cytotoxic for Activated Macrophages by Egan, P J, Carding, SR

“…Although gamma delta T cells are involved in the regulation of inflammation after infection, their precise function is not known. Intraperitoneal infection of…”
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Pulmonary dendritic cells and alveolar macrophages are regulated by γδ T cells during the resolution of S. pneumoniae-induced inflammation by Kirby, AC, Newton, DJ, Carding, SR, Kaye, PM

“…γδ T cells commonly associate with mucosal and epithelial sites, fulfilling a variety of immunoregulatory functions. While lung γδ T cells have…”
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Colonic Dendritic Cells, Intestinal Inflammation, and T Cell-Mediated Bone Destruction Are Modulated by Recombinant Osteoprotegerin by Ashcroft, A.J, Cruickshank, S.M, Croucher, P.I, Perry, M.J, Rollinson, S, Lippitt, J.M, Child, J.A, Dunstan, C, Felsburg, P.J, Morgan, G.J, Carding, S.R

“…Autoimmune associated bone disease and intestinal inflammation are closely linked with deregulation and hyperactivation of autoreactive CD4 T cells. How these…”
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The importance of gamma delta T cells in the resolution of pathogen-induced inflammatory immune responses by Carding, S R, Egan, P J

“…The aim of our research is to determine the biological function of gamma delta lymphocytes and in particular the role they play in microbial immunity. Although…”
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γδT cell-mediated regulation of chemokine producing macrophages during Listeria monocytogenes infection-induced inflammation by Tramonti, D, Rhodes, K, Martin, N, Dalton, JE, Andrew, E, Carding, SR

“…Infection of γδT cell-deficient (TcRδ⁻/⁻) mice with the intracellular bacterium Listeria monocytogenes (Lm) results in an exacerbated inflammatory response…”
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Roles of alpha beta and gamma delta T cell subsets in viral immunity by Doherty, P C, Allan, W, Eichelberger, M, Carding, S R

“…The current status of T-cell subset involvement in viral immunity is summarized for experimental studies in mice. The immunobiology of the normal host response…”
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A Requirement for IL-2/IL-2 Receptor Signaling in Intrathymic Negative Selection by Bassiri, Hamid, Carding, Simon R

“…The nature of the signals that influence thymocyte selection and determine the fate of CD4(+)8(+) (double positive) thymocytes remains unclear. Cytokines…”
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Involvement of the Fas/Fas ligand pathway in activation-induced cell death of mycobacteria-reactive human gamma delta T cells: a mechanism for the loss of gamma delta T cells in patients with pulmonary tuberculosis by Li, B, Bassiri, H, Rossman, M D, Kramer, P, Eyuboglu, A F, Torres, M, Sada, E, Imir, T, Carding, S R

“…Although the identity of T cells involved in the protection against Mycobacterium tuberculosis (Mtb) in humans remain unknown, patients with pulmonary…”
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Extrathymic origin of human gamma delta T cells during fetal development by McVay, LD, Carding, SR

“…We have identified the first TCRs to be generated in vivo during normal human fetal development. Before thymic formation, the liver is a site of generation for…”
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Expression and function of TLR2, TLR4, and Nod2 in primary canine colonic epithelial cells by Swerdlow, Mathew P., Kennedy, Douglas R., Kennedy, Jeffrey S., Washabau, Robert J., Henthorn, Paula S., Moore, Peter F., Carding, Simon R., Felsburg, Peter J.

“…The gut maintains a delicate balance between the downregulation of inflammatory reactions to commensal bacteria and the capacity to respond to pathogens with…”
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Disease-specific changes in gamma delta T cell repertoire and function in patients with pulmonary tuberculosis by Li, Baiqing, Rossman, MD, Imir, T, Oner-Eyuboglu, A F, Lee, Chung Wa, Biancaniello, R, Carding, SR

“…Although gamma delta T cells are known to contain the highest frequency of mycobacteria-reactive cells in humans and numerous studies have suggested that they…”
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The relationship of IL-4- and IFN gamma-producing T cells studied by lineage ablation of IL-4-producing cells by Kamogawa, Y, Minasi, L A, Carding, S R, Bottomly, K, Flavell, R A

“…Subsets of CD4 T cells are defined by the cytokines that they produce; these cytokines determine the effector function of these cells. Cloned CD4 T cells fall…”
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Lymphoid Hyperplasia, Autoimmunity, and Compromised Intestinal Intraepithelial Lymphocyte Development in Colitis-Free Gnotobiotic IL-2-Deficient Mice by Contractor, Nikhat V, Bassiri, Hamid, Reya, Tannishtha, Park, Audrey Y, Baumgart, Daniel C, Wasik, Mariusz A, Emerson, Stephen G, Carding, Simon R

“…IL-2-deficient (IL-2(-/-)) mice develop disorders of the hemopoietic and immune systems characterized by anemia, lymphocytic hyperplasia, and colitis. The…”
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Engineering of the gut commensal bacterium Bacteroides ovatus to produce and secrete biologically active murine interleukin‐2 in response to xylan by Farrar, M.D., Whitehead, T.R., Lan, J., Dilger, P., Thorpe, R., Holland, K.T., Carding, S.R.

“…Aims:  The aim of this work was to engineer a gut commensal bacterium, Bacteroidesovatus, to produce and secrete a biologically active cytokine in a regulated…”
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The Generation of Human gamma delta T Cell Repertoires During Fetal Development by McVay, L D, Jaswal, S S, Kennedy, C, Hayday, A, Carding, SR

“…The nature of how human gamma delta T cells are normally generated is not clear. We have used an RT-PCR assay and DNA sequencing to identify and compare delta…”
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Inflammatory bowel disease: cause and immunobiology by Baumgart, D C, Carding, SR

“…Crohn's disease and ulcerative colitis are idiopathic inflammatory bowel disorders. In this paper, we discuss how environmental factors (eg, geography,…”
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Plasma Membrane Expression of Heat Shock Protein 60 In Vivo in Response to Infection by BELLES, C, KUHL, A, NOSHENY, R, CARDING, S. R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Interferon γ inhibits apoptotic cell death in B cell chronic lymphocytic leukemia by BUSCHLE, M, CAMPANA, D, CARDING, S. R, RICHARD, C, HOFFBRAND, A. V, BRENNER, M. K

“…The malignant, CD5+ B lymphocytes of B cell chronic lymphocytic leukemia (B-CLL) die by apoptosis in vitro. This is in contrast to the prolonged life span of…”
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