Search Results - "Cardenas, Paula P."
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Double-strand break repair in bacteria: a view from Bacillus subtilis
Published in FEMS microbiology reviews (01-11-2011)“…Abstract In all living organisms, the response to double-strand breaks (DSBs) is critical for the maintenance of chromosome integrity. Homologous recombination…”
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RecX facilitates homologous recombination by modulating RecA activities
Published in PLoS genetics (01-12-2012)“…The Bacillus subtilis recH342 strain, which decreases interspecies recombination without significantly affecting the frequency of transformation with homogamic…”
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Lymphocyte integration of complement cues
Published in Seminars in cell & developmental biology (01-01-2019)“…We address current data, views and puzzles on the emerging topic of regulation of lymphocytes by complement proteins or fragments. Such regulation is believed…”
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Early steps of double-strand break repair in Bacillus subtilis
Published in DNA repair (01-03-2013)“…All organisms rely on integrated networks to repair DNA double-strand breaks (DSBs) in order to preserve the integrity of the genetic information, to…”
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Bacillus subtilis polynucleotide phosphorylase 3′-to-5′ DNase activity is involved in DNA repair
Published in Nucleic acids research (01-07-2009)“…In the presence of Mn2+, an activity in a preparation of purified Bacillus subtilis RecN degrades single-stranded (ss) DNA with a 3′ → 5′ polarity. This…”
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Polynucleotide phosphorylase exonuclease and polymerase activities on single-stranded DNA ends are modulated by RecN, SsbA and RecA proteins
Published in Nucleic acids research (01-11-2011)“…Bacillus subtilis pnpA gene product, polynucleotide phosphorylase (PNPase), is involved in double-strand break (DSB) repair via homologous recombination (HR)…”
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Detection of the Early Stage of Recombinational DNA Repair by Silicon Nanowire Transistors
Published in Nano letters (14-03-2012)“…A silicon nanowire-based biosensor has been designed and applied for label-free and ultrasensitive detection of the early stage of recombinational DNA repair…”
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Dynamic structures of Bacillus subtilis RecN-DNA complexes
Published in Nucleic acids research (01-01-2008)“…Genetic and cytological evidences suggest that Bacillus subtilis RecN acts prior to and after end-processing of DNA double-strand ends via homologous…”
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Nonsense CD247 mutations show dominant-negative features in T-cell receptor expression and function
Published in Journal of allergy and clinical immunology (01-10-2024)“…[Display omitted] The invariant TCR ζ/CD247 homodimer is crucial for TCR/CD3 expression and signaling through its 3 immunoreceptor tyrosine-based activation…”
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DNA double strand break end-processing and RecA induce RecN expression levels in Bacillus subtilis
Published in DNA repair (01-02-2014)“…•Bacillus subtilis RecN is among the first responders to DNA double strand breaks (DSBs).•Two major signaling-related cascades (SOS and DSBR) are induced upon…”
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Bacillus subtilis RarA Acts as a Positive RecA Accessory Protein
Published in Frontiers in microbiology (13-02-2020)“…Ubiquitous RarA AAA ATPases play crucial roles in the cellular response to blocked replication forks in pro- and eukaryotes. Here, we provide evidence that…”
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CD3G or CD3D Knockdown in Mature, but Not Immature, T Lymphocytes Similarly Cripples the Human TCRαβ Complex
Published in Frontiers in cell and developmental biology (25-06-2021)“…The human αβ T-cell receptor (TCR) is composed of a variable heterodimer (TCRαβ) and three invariant dimers (CD3γε, CD3δε, and ζζ/CD247 2 ). The role of each…”
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MHC class I genes in the owl monkey: mosaic organisation, convergence and loci diversity
Published in Immunogenetics (New York) (01-02-2005)“…The MHC class I molecule plays an important role in immune response, pathogen recognition and response against vaccines and self- versus non-self-recognition…”
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High level of conservation in Plasmodium vivax merozoite surface protein 4 (PvMSP4)
Published in Infection, genetics and evolution (01-10-2005)“…Plasmodium vivax merozoite surface protein 4 (PvMSP4) has been considered to be a promising malarial vaccine candidate. The antigenic diversity displayed by…”
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The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants
Published in Science (American Association for the Advancement of Science) (01-03-2024)“…We describe humans with rare biallelic loss-of-function variants impairing pre-α T cell receptor (pre-TCRα) expression. Low circulating naive αβ T cell counts…”
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Nonsense CD247 mutations show dominant-negative features in TCR expression and function
Published in Journal of allergy and clinical immunology (09-07-2024)“…The invariant TCRζ/CD247 homodimer is crucial for TCR/CD3 expression and signaling through its three immunoreceptor tyrosine-based activation motifs (ITAMs)…”
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New human combined immunodeficiency caused by interferon regulatory factor 4 (IRF4) deficiency inherited by uniparental isodisomy
Published in Journal of allergy and clinical immunology (01-05-2018)“…Genetic analysis using a next-generation sequencing (NGS)–customized panel allowed us to exclude mutations in all previously reported PID-related genes…”
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