Search Results - "Cardelli, Luca"

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  1. 1

    A programming language for composable DNA circuits by Phillips, Andrew, Cardelli, Luca

    Published in Journal of the Royal Society interface (06-08-2009)
    “…Recently, a range of information-processing circuits have been implemented in DNA by using strand displacement as their main computational mechanism. Examples…”
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    Journal Article
  2. 2

    The Cell Cycle Switch Computes Approximate Majority by Cardelli, Luca, Csikász-Nagy, Attila

    Published in Scientific reports (13-09-2012)
    “…Both computational and biological systems have to make decisions about switching from one state to another. The ‘Approximate Majority’ computational algorithm…”
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    Journal Article
  3. 3

    From electric circuits to chemical networks by Cardelli, Luca, Tribastone, Mirco, Tschaikowski, Max

    Published in Natural computing (01-03-2020)
    “…Electric circuits manipulate electric charge and magnetic flux via a small set of discrete components to implement useful functionality over continuous…”
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    Journal Article
  4. 4

    The Beacon Calculus: A formal method for the flexible and concise modelling of biological systems by Boemo, Michael A, Cardelli, Luca, Nieduszynski, Conrad A

    Published in PLoS computational biology (01-03-2020)
    “…Biological systems are made up of components that change their actions (and interactions) over time and coordinate with other components nearby. Together with…”
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    Journal Article
  5. 5

    Chemical reaction network designs for asynchronous logic circuits by Cardelli, Luca, Kwiatkowska, Marta, Whitby, Max

    Published in Natural computing (01-03-2018)
    “…Chemical reaction networks (CRNs) are a versatile language for describing the dynamical behaviour of chemical kinetics, capable of modelling a variety of…”
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    Journal Article
  6. 6

    Abstractions for DNA circuit design by Lakin, Matthew R., Youssef, Simon, Cardelli, Luca, Phillips, Andrew

    Published in Journal of the Royal Society interface (07-03-2012)
    “…DNA strand displacement techniques have been used to implement a broad range of information processing devices, from logic gates, to chemical reaction…”
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    Journal Article
  7. 7

    Design and analysis of DNA strand displacement devices using probabilistic model checking by Lakin, Matthew R., Parker, David, Cardelli, Luca, Kwiatkowska, Marta, Phillips, Andrew

    Published in Journal of the Royal Society interface (07-07-2012)
    “…Designing correct, robust DNA devices is difficult because of the many possibilities for unwanted interference between molecules in the system. DNA strand…”
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    Journal Article
  8. 8
  9. 9

    Evolution of opposing regulatory interactions underlies the emergence of eukaryotic cell cycle checkpoints by Hernansaiz-Ballesteros, Rosa D., Földi, Csenge, Cardelli, Luca, Nagy, László G., Csikász-Nagy, Attila

    Published in Scientific reports (27-05-2021)
    “…In eukaryotes the entry into mitosis is initiated by activation of cyclin-dependent kinases (CDKs), which in turn activate a large number of protein kinases to…”
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    Journal Article
  10. 10

    A Language for Modeling and Optimizing Experimental Biological Protocols by Cardelli, Luca, Kwiatkowska, Marta, Laurenti, Luca

    Published in Computation (01-10-2021)
    “…Automation is becoming ubiquitous in all laboratory activities, moving towards precisely defined and codified laboratory protocols. However, the integration…”
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    Journal Article
  11. 11

    Biomolecular mechanisms for signal differentiation by Alexis, Emmanouil, Schulte, Carolin C.M., Cardelli, Luca, Papachristodoulou, Antonis

    Published in iScience (17-12-2021)
    “…Cells can sense temporal changes of molecular signals, allowing them to predict environmental variations and modulate their behavior. This paper elucidates…”
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    Journal Article
  12. 12

    Efficient Switches in Biology and Computer Science by Cardelli, Luca, Hernansaiz-Ballesteros, Rosa D, Dalchau, Neil, Csikász-Nagy, Attila

    Published in PLoS computational biology (01-01-2017)
    “…Luca Cardelli Affiliations Microsoft Research, Cambridge, United Kingdom, Department of Computer Science, University of Oxford, Oxford, United Kingdom Rosa D…”
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    Journal Article
  13. 13

    Phosphorelays provide tunable signal processing capabilities for the cell by Kothamachu, Varun B, Feliu, Elisenda, Wiuf, Carsten, Cardelli, Luca, Soyer, Orkun S

    Published in PLoS computational biology (01-11-2013)
    “…Achieving a complete understanding of cellular signal transduction requires deciphering the relation between structural and biochemical features of a signaling…”
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    Journal Article
  14. 14

    Transcriptional regulation is a major controller of cell cycle transition dynamics by Romanel, Alessandro, Jensen, Lars Juhl, Cardelli, Luca, Csikász-Nagy, Attila

    Published in PloS one (06-01-2012)
    “…DNA replication, mitosis and mitotic exit are critical transitions of the cell cycle which normally occur only once per cycle. A universal control mechanism…”
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    Journal Article
  15. 15

    Two-Domain DNA Strand Displacement by Cardelli, Luca

    “…We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks…”
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  16. 16

    A peptide filtering relation quantifies MHC class I peptide optimization by Dalchau, Neil, Phillips, Andrew, Goldstein, Leonard D, Howarth, Mark, Cardelli, Luca, Emmott, Stephen, Elliott, Tim, Werner, Joern M

    Published in PLoS computational biology (01-10-2011)
    “…Major Histocompatibility Complex (MHC) class I molecules enable cytotoxic T lymphocytes to destroy virus-infected or cancerous cells, thereby preventing…”
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    Journal Article
  17. 17

    Morphisms of reaction networks that couple structure to function by Cardelli, Luca

    Published in BMC systems biology (15-08-2014)
    “…The mechanisms underlying complex biological systems are routinely represented as networks. Network kinetics is widely studied, and so is the connection…”
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    Journal Article
  18. 18

    Continuous Markovian Logics - Axiomatization and Quantified Metatheory by Mardare, Radu, Cardelli, Luca, Larsen, Kim G.

    Published in Logical methods in computer science (01-01-2012)
    “…Continuous Markovian Logic (CML) is a multimodal logic that expresses quantitative and qualitative properties of continuous-time labelled Markov processes with…”
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  19. 19

    On process rate semantics by Cardelli, Luca

    Published in Theoretical computer science (14-02-2008)
    “…We provide translations between process algebra and systems of chemical reactions. We show that the translations preserve discrete-state (stochastic) and…”
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    Journal Article Conference Proceeding
  20. 20

    Strand algebras for DNA computing by Cardelli, Luca

    Published in Natural computing (01-03-2011)
    “…We present a process algebra for DNA computing, discussing compilation of other formal systems into the algebra, and compilation of the algebra into DNA…”
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    Journal Article