Search Results - "Cardell, Susanna L"
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Type II NKT Cells: An Elusive Population With Immunoregulatory Properties
Published in Frontiers in immunology (28-08-2018)“…Natural killer T (NKT) cells are unique unconventional T cells that are reactive to lipid antigens presented on the non-polymorphic major histocompatibility…”
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The Yin and Yang of Invariant Natural Killer T Cells in Tumor Immunity-Suppression of Tumor Immunity in the Intestine
Published in Frontiers in immunology (10-01-2018)“…CD1d-restricted invariant natural killer T (iNKT) cells are known as early responding, potent regulatory cells of immune responses. Besides their established…”
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Natural Killer T-Cell Agonist α-Galactosylceramide and PD-1 Blockade Synergize to Reduce Tumor Development in a Preclinical Model of Colon Cancer
Published in Frontiers in immunology (20-10-2020)“…Murine and human invariant natural killer T (iNKT) lymphocytes are activated by α-galactosylceramide (α-GalCer) presented on CD1d. α-GalCer was first described…”
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C1QTNF3 is Upregulated During Subcutaneous Adipose Tissue Remodeling and Stimulates Macrophage Chemotaxis and M1-Like Polarization
Published in Frontiers in immunology (02-06-2022)“…The adipose tissue undergoes substantial tissue remodeling during weight gain-induced expansion as well as in response to the mechanical and immunological…”
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Invariant NKT cells limit activation of autoreactive CD1d-positive B cells
Published in The Journal of experimental medicine (10-05-2010)“…Faulty activation of autoreactive B cells is a hallmark of autoimmune diseases like systemic lupus erythematosus (SLE). An important feature restricting…”
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Sulfatide Attenuates Experimental Staphylococcus aureus Sepsis through a CD1d-Dependent Pathway
Published in Infection and Immunity (01-04-2013)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Multiple tissue-specific isoforms of sulfatide activate CD1d-restricted type II NKT cells
Published in European journal of immunology (01-07-2009)“…The glycosphingolipid sulfatide (SO₃-3Galβ1Cer) is a demonstrated ligand for a subset of CD1d-restricted NKT cells, which could regulate experimental…”
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High Interferon-γ Uniquely in Vδ1 T Cells Correlates with Markers of Inflammation and Axonal Damage in Early Multiple Sclerosis
Published in Frontiers in immunology (09-03-2017)“…We have identified a population of T lymphocytes in peripheral blood, Vδ1 TCRγδ T lymphocytes, which unexpectedly was uniquely expressing high production of…”
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CD4(+) type II NKT cells mediate ICOS and programmed death-1-dependent regulation of type 1 diabetes
Published in The Journal of immunology (1950) (01-04-2012)“…Type 1 diabetes (T1D) is a chronic autoimmune disease that results from T cell-mediated destruction of pancreatic β cells. CD1d-restricted NKT lymphocytes have…”
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The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formation
Published in iScience (19-05-2023)“…Germinal center (GC) formation and antibody production in lymph node follicles require coordinated interactions between B-cells, T-cells and dendritic cells…”
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Promotion or Suppression of Murine Intestinal Polyp Development by iNKT Cell Directed Immunotherapy
Published in Frontiers in immunology (2019)“…The glycosphingolipid α-galactosylceramide (α-GalCer) is a well-described immune activator with strong anti-tumor properties in animal models. It is presented…”
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Altered expression of Butyrophilin (BTN) and BTN‐like (BTNL) genes in intestinal inflammation and colon cancer
Published in Immunity, Inflammation and Disease (01-06-2016)“…Several Butyrophilin (BTN) and Btn‐like (BTNL) molecules control T lymphocyte responses, and are genetically associated with inflammatory disorders and cancer…”
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Structure-Function Implications of the Ability of Monoclonal Antibodies Against α-Galactosylceramide-CD1d Complex to Recognize β-Mannosylceramide Presentation by CD1d
Published in Frontiers in immunology (09-10-2019)“…iNKT cells are CD1d-restricted T cells recognizing lipid antigens. The prototypic iNKT cell-agonist α-galactosylceramide (α-GalCer) alongside compounds with…”
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Prevention of Diabetes in Nonobese Diabetic Mice Mediated by CD1d-Restricted Nonclassical NKT Cells
Published in The Journal of immunology (1950) (01-09-2004)“…A role for regulatory lymphocytes has been demonstrated in the pathogenesis of type 1 diabetes in the NOD mouse but the nature of these cells is debated…”
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The role of CD1d‐restricted NK T lymphocytes in the immune response to oral infection with Salmonella typhimurium
Published in European journal of immunology (01-07-2005)“…CD1d‐restricted natural killer T (NKT) cells belong to the innate‐like lymphocytes which respond rapidly to stress and infectious challenge. We have studied…”
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Defining a novel subset of CD1d‐dependent type II natural killer T cells using natural killer cell‐associated markers
Published in Scandinavian journal of immunology (01-09-2019)“…Natural killer T (NKT) cells are αβ T cell receptor (TCR) expressing innate‐like T cells that display natural killer (NK) cell markers. Based on TCR…”
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Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor
Published in Nature immunology (01-09-2012)“…Natural killer T cells (NKT cells) recognize lipid antigens presented by CD1d. Zajonc and Rossjohn and their colleagues describe molecular interactions between…”
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Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS
Published in Journal of neurochemistry (01-08-2018)“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Several biomarkers including proteins and lipids have…”
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Dysregulation of CD1d-Restricted Type II Natural Killer T Cells Leads to Spontaneous Development of Colitis in Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2012)“…Background & Aims CD1d-restricted natural killer (NK) T cells are a subset of immunoregulatory T cells that comprise type I (express the semi-invariant T-cell…”
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Cerebrospinal fluid sulfatide isoforms lack diagnostic utility in separating progressive from relapsing-remitting multiple sclerosis
Published in Multiple sclerosis and related disorders (01-06-2023)“…Multiple sclerosis (MS) is an immune-mediated demyelinating disorder of the central nervous system. The glycosphingolipid sulfatide, a lipid particularly…”
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