Search Results - "Cardaropoli, Simona"

Helicobacter pylori and pregnancy-related disorders by Cardaropoli, Simona, Rolfo, Alessandro, Todros, Tullia

“…Helicobacter pylori(H.pylori)infection is investigated in gastric diseases even during pregnancy.In particular,this Gram-negative bacterium seems to be…”
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Role of the Macrophage Migration Inhibitory Factor in the Pathophysiology of Pre-Eclampsia by Todros, Tullia, Paulesu, Luana, Cardaropoli, Simona, Rolfo, Alessandro, Masturzo, Bianca, Ermini, Leonardo, Romagnoli, Roberta, Ietta, Francesca

“…Proinflammatory cytokines are produced in pregnancy in response to the invading pathogens and/or nonmicrobial causes such as damage-associated molecules and…”
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Pro-inflammatory profile of preeclamptic placental mesenchymal stromal cells: new insights into the etiopathogenesis of preeclampsia by Rolfo, Alessandro, Giuffrida, Domenica, Nuzzo, Anna Maria, Pierobon, Daniele, Cardaropoli, Simona, Piccoli, Ettore, Giovarelli, Mirella, Todros, Tullia

“…The objective of the present study was to evaluate whether placental mesenchymal stromal cells (PDMSCs) derived from normal and preeclamptic (PE) chorionic…”
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Exploring New Drug Repurposing Opportunities for MEK Inhibitors in RASopathies: A Comprehensive Review of Safety, Efficacy, and Future Perspectives of Trametinib and Selumetinib by Gazzin, Andrea, Fornari, Federico, Cardaropoli, Simona, Carli, Diana, Tartaglia, Marco, Ferrero, Giovanni Battista, Mussa, Alessandro

“…The RASopathies are a group of syndromes caused by genetic variants that affect the RAS-MAPK signaling pathway, which is essential for cell response to diverse…”
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Pregnancy Epigenetic Signature in T Helper 17 and T Regulatory Cells in Multiple Sclerosis by Iannello, Andrea, Rolla, Simona, Maglione, Alessandro, Ferrero, Giulio, Bardina, Valentina, Inaudi, Ilenia, De Mercanti, Stefania, Novelli, Francesco, D'Antuono, Lucrezia, Cardaropoli, Simona, Todros, Tullia, Turrini, Maria Vittoria, Cordioli, Cinzia, Puorro, Giorgia, Marsili, Angela, Lanzillo, Roberta, Brescia Morra, Vincenzo, Cordero, Francesca, De Bortoli, Michele, Durelli, Luca, Visconti, Andrea, Cutrupi, Santina, Clerico, Marinella

“…Increasing evidence supports the anti-inflammatory role of estrogens in Multiple Sclerosis (MS), originating from the observation of reduction in relapse rates…”
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Helicobacter pylori＇s virulence and infection persistence define pre-eclampsia complicated by fetal growth retardation by Cardaropoli, Simona

“…AIM： To better understand the pathogenic role of Helicobacter pylori （H. pylori） in pre-eclampsia （PE）, and whether it is associated or not with fetal growth…”
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Prenatal features in Beckwith-Wiedemann syndrome and indications for prenatal testing by Carli, Diana, Bertola, Chiara, Cardaropoli, Simona, Ciuffreda, Valentina Pia, Pieretto, Marta, Ferrero, Giovanni Battista, Mussa, Alessandro

“…Most cases of Beckwith-Wiedemann spectrum (BWSp) are diagnosed after birth and few studies evaluated the prenatal phenotype; here, we investigate these aspects…”
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Epidemiology of the disorders of the Pik3ca-related overgrowth spectrum (Pros) by Reynolds, Giuseppe, Cardaropoli, Simona, Carli, Diana, Luca, Maria, Gazzin, Andrea, Coppo, Paola, La Selva, Roberta, Piglionica, Marilidia, Bagnulo, Rosanna, Turchiano, Antonella, Ranieri, Carlotta, Resta, Nicoletta, Mussa, Alessandro

“…PIK3CA pathogenic variants are responsible for a group of overgrowth syndromes, collectively known as PIK3CA-Related Overgrowth Spectrum (PROS). These…”
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The somatic p.T81dup variant in AKT3 gene underlies a mild cerebral phenotype and expands the spectrum including capillary malformation and lateralized overgrowth by Luca, Maria, Piglionica, Marilidia, Bagnulo, Rosanna, Cardaropoli, Simona, Carli, Diana, Turchiano, Antonella, Coppo, Paola, Pantaleo, Antonino, Iacoviello, Matteo, Ferrero, Giovanni Battista, Mussa, Alessandro, Resta, Nicoletta

“…Heterozygous germline or somatic variants in AKT3 gene can cause isolated malformations of cortical development (MCDs) such as focal cortical dysplasia,…”
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Evolution over Time of Leg Length Discrepancy in Patients with Syndromic and Isolated Lateralized Overgrowth by Carli, Diana, De Pellegrin, Maurizio, Franceschi, Luisa, Zinali, Federica, Paonessa, Matteo, Spolaore, Simone, Cardaropoli, Simona, Cravino, Mattia, Marcucci, Lorenzo, Andreacchio, Antonio, Resta, Nicoletta, Ferrero, Giovanni Battista, Mussa, Alessandro

“…To provide information on evolution over time of leg length discrepancy in patients with syndromic and isolated lateralized overgrowth. This retrospective…”
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Molecular Basis and Diagnostic Approach to Isolated and Syndromic Lateralized Overgrowth in Childhood by Bellucca, Simone, Carli, Diana, Gazzin, Andrea, Massuras, Stefania, Cardaropoli, Simona, Luca, Maria, Coppo, Paola, Caprioglio, Mirko, La Selva, Roberta, Piglionica, Marilidia, Bontempo, Piera, D'Elia, Gemma, Bagnulo, Rosanna, Ferrero, Giovanni Battista, Resta, Nicoletta, Mussa, Alessandro

“…To demonstrate a high-yield molecular diagnostic workflow for lateralized overgrowth (LO), a congenital condition with abnormal enlargement of body parts, and…”
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Phenotype evolution and health issues of adults with Beckwith‐Wiedemann syndrome by Gazzin, Andrea, Carli, Diana, Sirchia, Fabio, Molinatto, Cristina, Cardaropoli, Simona, Palumbo, Giuseppe, Zampino, Giuseppe, Ferrero, Giovanni Battista, Mussa, Alessandro

“…Background Beckwith‐Wiedemann syndrome (BWS) phenotype usually mitigates with age and data on adulthood are limited. Our study aims at reporting phenotype…”
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Genetic and molecular evidence for complement dysregulation in patients with HELLP syndrome by Bazzan, Mario, Todros, Tullia, Tedeschi, Silvana, Ardissino, Gianluigi, Cardaropoli, Simona, Stella, Stefania, Montaruli, Barbara, Marchese, Cristiana, Roccatello, Dario, Cugno, Massimo

“…HELLP (Hemolysis, elevated liver enzymes and low platelets) syndrome is a severe and acute pregnancy-related disorder that occurs in approximately 2.5 per 1000…”
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Lateralized and Segmental Overgrowth in Children by Mussa, Alessandro, Carli, Diana, Cardaropoli, Simona, Ferrero, Giovanni Battista, Resta, Nicoletta

“…Congenital disorders of lateralized or segmental overgrowth (LO) are heterogeneous conditions with increased tissue growth in a body region. LO can affect…”
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Helicobacter pylori's virulence and infection persistence define pre-eclampsia complicated by fetal growth retardation by Cardaropoli, Simona, Rolfo, Alessandro, Piazzese, Annalisa, Ponzetto, Antonio, Todros, Tullia

“…To better understand the pathogenic role of Helicobacter pylori (H. pylori) in pre-eclampsia (PE), and whether it is associated or not with fetal growth…”
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Successful treatment with MEK‐inhibitor in a patient with NRAS‐related cutaneous skeletal hypophosphatemia syndrome by Carli, Diana, Cardaropoli, Simona, Tessaris, Daniele, Coppo, Paola, La Selva, Roberta, Cesario, Claudia, Lepri, Francesca Romana, Pullano, Verdiana, Palumbo, Martina, Ramenghi, Ugo, Brusco, Alfredo, Medico, Enzo, De Sanctis, Luisa, Ferrero, Giovanni Battista, Mussa, Alessandro

“…Cutaneous skeletal hypophosphatemia syndrome (CSHS) is caused by somatic mosaic NRAS variants and characterized by melanocytic/sebaceous naevi, eye, and brain…”
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Skewed X-chromosome inactivation in unsolved neurodevelopmental disease cases can guide re-evaluation For X-linked genes by Giovenino, Chiara, Trajkova, Slavica, Pavinato, Lisa, Cardaropoli, Simona, Pullano, Verdiana, Ferrero, Enza, Sukarova-Angelovska, Elena, Carestiato, Silvia, Salmin, Paola, Rinninella, Antonina, Battaglia, Anthony, Bertoli, Luca, Fadda, Antonio, Palermo, Flavia, Carli, Diana, Mussa, Alessandro, Dimartino, Paola, Bruselles, Alessandro, Froukh, Tawfiq, Mandrile, Giorgia, Pasini, Barbara, De Rubeis, Silvia, Buxbaum, Joseph D, Pippucci, Tommaso, Tartaglia, Marco, Rossato, Marzia, Delledonne, Massimo, Ferrero, Giovanni Battista, Brusco, Alfredo

“…Despite major advances in genome technology and analysis, >50% of patients with a neurodevelopmental disorder (NDD) remain undiagnosed after extensive…”
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Helicobacter pylori seropositivity and pregnancy-related diseases: a prospective cohort study by Cardaropoli, Simona, Giuffrida, Domenica, Piazzese, Annalisa, Todros, Tullia

“…Highlights • H. pylori seropositivity before 20 weeks is associated with gestational diabetes. • Maternal H. pylori seropositivity is independently associated…”
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A new case of Smith‐Kingsmore syndrome with somatic MTOR pathogenic variant expands the phenotypic spectrum to lateralized overgrowth by Carli, Diana, Ferrero, Giovanni Battista, Fusillo, Anna, Coppo, Paola, La Selva, Roberta, Zinali, Federica, Cardaropoli, Simona, Ranieri, Carlotta, Iacoviello, Matteo, Resta, Nicoletta, Mussa, Alessandro

“…Smith‐Kingsmore syndrome (SKS) is a rare autosomal dominant disorder caused by heterozygous germline activating pathogenic variants in mammalian target of…”
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Lateralized overgrowth with vascular malformation caused by a somatic PTPN11 pathogenic variant: Another piece added to the puzzle of mosaic RASopathies by Mussa, Alessandro, Turchiano, Antonella, Cardaropoli, Simona, Coppo, Paola, Pantaleo, Antonino, Bagnulo, Rosanna, Ranieri, Carlotta, Iacoviello, Matteo, Garganese, Antonella, Stella, Alessandro, Vallero, Stefano Gabriele, Bertin, Daniele, Santoro, Federica, Carli, Diana, Ferrero, Giovanni Battista, Resta, Nicoletta

“…Lateralized/segmental overgrowth disorders (LOs) encompass a heterogeneous group of congenital conditions with excessive body tissue growth. Documented…”
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