Search Results - "Carballeira, José Daniel"

Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes by Reetz, Manfred T, Carballeira, José Daniel

“…Iterative saturation mutagenesis (ISM) is a new and efficient method for the directed evolution of functional enzymes. It reduces the necessary molecular…”
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A high security double lock and key mechanism in HUH relaxases controls oriT-processing for plasmid conjugation by Carballeira, José Daniel, González-Pérez, Blanca, Moncalián, Gabriel, de la Cruz, Fernando

“…Relaxases act as DNA selection sieves in conjugative plasmid transfer. Most plasmid relaxases belong to the HUH endonuclease family. TrwC, the relaxase of…”
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Directed evolution and axial chirality: optimization of the enantioselectivity of Pseudomonas aeruginosa lipase towards the kinetic resolution of a racemic allene by Carballeira, José Daniel, Krumlinde, Patrik, Bocola, Marco, Vogel, Andreas, Reetz, Manfred T, Bäckvall, Jan E

“…Directed evolution of Pseudomonas aeruginosa lipase by the use of combinatorial active site saturation test (CAST) criteria provided a highly enantioselective…”
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Expanding the Range of Substrate Acceptance of Enzymes: Combinatorial Active-Site Saturation Test by Reetz, Manfred T., Bocola, Marco, Carballeira, José Daniel, Zha, Dongxing, Vogel, Andreas

“…CASTing for success: The traditional problem of expanding the range of substrate acceptance of enzymes can be solved by creating focused libraries of mutants…”
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Enzyme promiscuity: first protein-catalyzed Morita–Baylis–Hillman reaction by Reetz, Manfred T., Mondière, Régis, Carballeira, José Daniel

“…The Morita–Baylis–Hillman reaction of cyclohexenone and p-nitro benzaldehyde is catalyzed by carrier proteins such as serum albumins or enzymes such as certain…”
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Expanding the Substrate Scope of Enzymes: Combining Mutations Obtained by CASTing by Reetz, Manfred T., Carballeira, José Daniel, Peyralans, Jérôme, Höbenreich, Horst, Maichele, Andrea, Vogel, Andreas

“…In a previous paper, the combinatorial active‐site saturation test (CAST) was introduced as an effective strategy for the directed evolution of enzymes toward…”
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Historia clínica y receta electrónica: riesgos y beneficios detectados desde su implantación. Diseño, despliegue y usos seguros by Añel Rodríguez, Rosa María, García Alfaro, Irene, Bravo Toledo, Rafael, Carballeira Rodríguez, José Daniel

“…Las nuevas tecnologías de la información han transformado la manera de prestar la asistencia en los servicios de salud, impregnando casi todos los aspectos de…”
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Changing the recognition site of a conjugative relaxase by rational design by González-Pérez, Blanca, Carballeira, José Daniel, Moncalián, Gabriel, de la Cruz, Fernando

“…TrwC is a relaxase protein, which starts and finishes DNA processing during bacterial conjugation in plasmid R388. TrwC recognizes a specific sequence of DNA…”
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Learning from Directed Evolution: Further Lessons from Theoretical Investigations into Cooperative Mutations in Lipase Enantioselectivity by Reetz, Manfred T., Puls, Michael, Carballeira, José Daniel, Vogel, Andreas, Jaeger, Karl-Erich, Eggert, Thorsten, Thiel, Walter, Bocola, Marco, Otte, Nikolaj

“…An earlier experimental study, which involved the directed evolution of enantioselective lipase variants from Pseudomonas aeruginosa as catalysts in the…”
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Lipase from Pseudomonas stutzeri: Purification, homology modelling and rational explanation of the substrate binding mode by Maraite, Andy, Hoyos, Pilar, Carballeira, José Daniel, Cabrera, Álvaro C., Ansorge-Schumacher, Marion B., Alcántara, Andrés R.

“…[Display omitted] ► The lipase from Pseudomonas stutzeri has been purified from commercial sources. ► A homology modelling has been used to obtain a 3D model…”
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Electronic medical record and prescription: risks and benefits detected since its implementation. Safe designing, rollout and use by Añel Rodríguez, Rosa María, García Alfaro, Irene, Bravo Toledo, Rafael, Carballeira Rodríguez, José Daniel

“…New information technologies have transformed the way care is delivered within health services, permeating almost every aspect of health care. As the…”
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Biotransformation of cyclohexanone using immobilized Geotrichum candidum NCYC49 : Factors affecting the selectivity of the process by Carballeira, José Daniel, Álvarez, Emilio, Sinisterra, José Vicente

“…A screening of 416 microorganisms belonging to different taxonomical groups (bacteria, actinomycetes, yeasts and filamentous fungi) was performed looking for…”
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Receta electrónica: Limitaciones y posibles mejoras para asegurar una mayor adherencia a los tratamientos by García Alfaro, Irene, Carballeira Rodríguez, José Daniel

“…Background: The electronic prescription has meant an evolution in the quality of health care, but it has a series of deficiencies that compromise the adherence…”
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Biotransformation of cyclohexanone using immobilized Geotrichum candidum NCYC49 by Carballeira, José Daniel, Álvarez, Emilio, Sinisterra, José Vicente

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Electronic medical record and prescription: risks and benefits detected since its implementation. Safe designing, rollout and use by Añel Rodríguez, Rosa María, García Alfaro, Irene, Bravo Toledo, Rafael, Carballeira Rodríguez, José Daniel

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Electronic prescription: limitations and possible improvements to ensure greater adherence to treatments by García Alfaro, Irene, Carballeira Rodríguez, José Daniel

“…The electronic prescription has meant an evolution in the quality of health care, but it has a series of deficiencies that compromise the adherence to…”
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Expanding the Range of Substrate Acceptance of Enzymes: Combinatorial Active-Site Saturation Test by Reetz, Manfred T., Bocola, Marco, Carballeira, José Daniel, Zha, Dongxing, Vogel, Andreas

“…Mit CASTing zum Erfolg: Das bekannte Problem, die Substratakzeptanz von Enzymen zu erweitern, lässt sich dadurch lösen, dass fokussierte Mutantenbibliotheken…”
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Expanding the Range of Substrate Acceptance of Enzymes: Combinatorial Active‐Site Saturation Test by Reetz, Manfred T., Bocola, Marco, Carballeira, José Daniel, Zha, Dongxing, Vogel, Andreas

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Dispensación de medicamentos de prescripción y resolución de incidencias a partir de la entrada en vigor de la directiva 2011/62/UE by José Daniel Carballeira Rodríguez, Irene García Alfaro

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Dispensación de medicamentos de prescripción y resolución de incidencias a partir de la entrada en vigor de la directiva 2011/62/UE by José Daniel Carballeira Rodríguez, Irene García Alfaro

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