Search Results - "Carayol, Jerome"

Genetic Susceptibility Determines β-Cell Function and Fasting Glycemia Trajectories Throughout Childhood: A 12-Year Cohort Study (EarlyBird 76) by Carayol, Jerome, Hosking, Joanne, Pinkney, Jonathan, Marquis, Julien, Charpagne, Aline, Metairon, Sylviane, Jeffery, Alison, Hager, Jörg, Martin, Francois-Pierre

“…Previous studies suggested that childhood prediabetes may develop prior to obesity and be associated with relative insulin deficiency. We proposed that the…”
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Contribution of genetic ancestry and polygenic risk score in meeting vitamin B12 needs in healthy Brazilian children and adolescents by Fuzo, Carlos Alessandro, da Veiga Ued, Fábio, Moco, Sofia, Cominetti, Ornella, Métairon, Sylviane, Pruvost, Solenn, Charpagne, Aline, Carayol, Jerome, Torrieri, Raul, Silva, Wilson Araujo, Descombes, Patrick, Kaput, Jim, Monteiro, Jacqueline Pontes

“…Polymorphisms in genes related to the metabolism of vitamin B12 haven’t been examined in a Brazilian population. To (a) determine the correlation between the…”
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Converging Evidence for an Association of ATP2B2 Allelic Variants with Autism in Male Subjects by Carayol, Jérôme, Sacco, Roberto, Tores, Frédéric, Rousseau, Francis, Lewin, Patricia, Hager, Jorg, Persico, Antonio M

“…Background Autism is a severe developmental disorder, with strong genetic underpinnings. Previous genome-wide scans unveiled a linkage region spanning 3.5 Mb,…”
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Epilepsy in Simplex Autism Pedigrees is Much Lower Than the Rate in Multiplex Autism Pedigrees by Amiet, Claire, Gourfinkel-An, Isabelle, Laurent, Claudine, Carayol, Jérôme, Génin, Bérengère, Leguern, Eric, Tordjman, Sylvie, Cohen, David

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Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance by Matone, Alice, Scott-Boyer, Marie-Pier, Carayol, Jerome, Fazelzadeh, Parastoo, Lefebvre, Gregory, Valsesia, Armand, Charon, Celine, Vervoort, Jacques, Astrup, Arne, Saris, Wim H M, Morine, Melissa, Hager, Jörg

“…Weight loss success is dependent on the ability to refrain from regaining the lost weight in time. This feature was shown to be largely variable among…”
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Grape polyphenols decrease circulating branched chain amino acids in overfed adults by Bartova, Simona, Madrid-Gambin, Francisco, Fernández, Luis, Carayol, Jerome, Meugnier, Emmanuelle, Segrestin, Bérénice, Delage, Pauline, Vionnet, Nathalie, Boizot, Alexia, Laville, Martine, Vidal, Hubert, Marco, Santiago, Hager, Jörg, Moco, Sofia

“…Dietary polyphenols have long been associated with health benefits, including the prevention of obesity and related chronic diseases. Overfeeding was shown to…”
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Metabolic Differences between Dogs of Different Body Sizes by Kaput, Jim, Beloshapka, Alison, Carayol, Jerome, Slusky, Amanda R., Kennedy, Adam D., Dordevic, Nikola, Scott-Boyer, Marie-Pier, Lacroix, Sebastien, Middleton, Rondo P., Petzinger-Germain, Christina

“…Introduction. The domesticated dog, Canis lupus familiaris, has been selectively bred to produce extreme diversity in phenotype and genotype. Dogs have an…”
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Analysis of 1508 Plasma Samples by Capillary-Flow Data-Independent Acquisition Profiles Proteomics of Weight Loss and Maintenance'[S] by Bruderer, Roland, Muntel, Jan, Müller, Sebastian, Bernhardt, Oliver M., Gandhi, Tejas, Cominetti, Ornella, Macron, Charlotte, Carayol, Jérôme, Rinner, Oliver, Astrup, Arne, Saris, Wim H.M., Hager, Jörg, Valsesia, Armand, Dayon, Loïc, Reiter, Lukas

“…We established a robust capillary-flow data-independent acquisition MS platform capable of measuring 31 plasma proteomes per day without the need of repeated…”
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Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator by Carayol, Jérôme, Chabert, Christian, Di Cara, Alessandro, Armenise, Claudia, Lefebvre, Gregory, Langin, Dominique, Viguerie, Nathalie, Metairon, Sylviane, Saris, Wim H. M., Astrup, Arne, Descombes, Patrick, Valsesia, Armand, Hager, Jörg

“…Thousands of genetic variants have been associated with complex traits through genome-wide association studies. However, the functional variants or mechanistic…”
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Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism by Valsesia, Armand, Wang, Qiao-Ping, Gheldof, Nele, Carayol, Jérôme, Ruffieux, Hélène, Clark, Teleri, Shenton, Victoria, Oyston, Lisa J., Lefebvre, Gregory, Metairon, Sylviane, Chabert, Christian, Walter, Ondine, Mironova, Polina, Lau, Paulina, Descombes, Patrick, Viguerie, Nathalie, Langin, Dominique, Harper, Mary-Ellen, Astrup, Arne, Saris, Wim H., Dent, Robert, Neely, Greg G., Hager, Jörg

“…Hundreds of genetic variants have been associated with Body Mass Index (BMI) through genome-wide association studies (GWAS) using observational cohorts…”
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Molecular Biomarkers for Weight Control in Obese Individuals Subjected to a Multiphase Dietary Intervention by Bolton, Jennifer, Montastier, Emilie, Carayol, Jérôme, Bonnel, Sophie, Mir, Lucile, Marques, Marie-Adeline, Astrup, Arne, Saris, Wim, Iacovoni, Jason, Villa-Vialaneix, Nathalie, Valsesia, Armand, Langin, Dominique, Viguerie, Nathalie

“…Abstract Context Although calorie restriction has proven beneficial for weight loss, long-term weight control is variable between individuals. Objective To…”
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A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma by Ruffieux, Hélène, Carayol, Jérôme, Popescu, Radu, Harper, Mary-Ellen, Dent, Robert, Saris, Wim H M, Astrup, Arne, Hager, Jörg, Davison, Anthony C, Valsesia, Armand

“…Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not…”
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Assessing the impact of a combined analysis of four common low-risk genetic variants on autism risk by Carayol, Jerome, Schellenberg, Gerard D, Tores, Frederic, Hager, Jörg, Ziegler, Andreas, Dawson, Geraldine

“…Autism is a complex disorder characterized by deficits involving communication, social interaction, and repetitive and restrictive patterns of behavior. Twin…”
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Transcriptome profiling from adipose tissue during a low-calorie diet reveals predictors of weight and glycemic outcomes in obese, nondiabetic subjects by Armenise, Claudia, Lefebvre, Gregory, Carayol, Jérôme, Bonnel, Sophie, Bolton, Jennifer, Di Cara, Alessandro, Gheldof, Nele, Descombes, Patrick, Langin, Dominique, Saris, Wim HM, Astrup, Arne, Hager, Jörg, Viguerie, Nathalie, Valsesia, Armand

“…A low-calorie diet (LCD) reduces fat mass excess, improves insulin sensitivity, and alters adipose tissue (AT) gene expression, yet the relation with clinical…”
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Proteomics reveals unique plasma signatures in constitutional thinness by Cominetti, Ornella, Núñez Galindo, Antonio, Corthésy, John, Carayol, Jérôme, Germain, Natacha, Galusca, Bogdan, Estour, Bruno, Hager, Jörg, Gheldof, Nele, Dayon, Loïc

“…Purpose Studying the plasma proteome of control versus constitutionally thin (CT) individuals, exposed to overfeeding, may give insights into weight‐gain…”
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Persistent low body weight in humans is associated with higher mitochondrial activity in white adipose tissue by Ling, Yiin, Carayol, Jérôme, Galusca, Bogdan, Canto, Carles, Montaurier, Christophe, Matone, Alice, Vassallo, Irene, Minehira, Kaori, Alexandre, Virginie, Cominetti, Ornella, Núñez Galindo, Antonio, Corthésy, John, Dayon, Loïc, Charpagne, Aline, Métairon, Sylviane, Raymond, Frédéric, Descombes, Patrick, Casteillo, François, Peoc–h, Michel, Palaghiu, Radu, Féasson, Léonard, Boirie, Yves, Estour, Bruno, Hager, Jörg, Germain, Natacha, Gheldof, Nele

“…Constitutional thinness (CT) is a state of low but stable body weight (BMI ≤18 kg/m2). CT subjects have normal-range hormonal profiles and food intake but…”
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Apolipoprotein M: a novel adipokine decreasing with obesity and upregulated by calorie restriction by Sramkova, Veronika, Berend, Sarah, Siklova, Michaela, Caspar-Bauguil, Sylvie, Carayol, Jérôme, Bonnel, Sophie, Marques, Marie, Decaunes, Pauline, Kolditz, Catherine-Ines, Dahlman, Ingrid, Arner, Peter, Stich, Vladimir, Saris, Wim H M, Astrup, Arne, Valsesia, Armand, Rossmeislova, Lenka, Langin, Dominique, Viguerie, Nathalie

“…The adipose tissue (AT) is a secretory organ producing a wide variety of factors that participate in the genesis of metabolic disorders linked to excess fat…”
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Resistance to lean mass gain in constitutional thinness in free‐living conditions is not overpassed by overfeeding by Ling, Yiin, Galusca, Bogdan, Martin, François‐Pierre, Bartova, Simona, Carayol, Jérôme, Moco, Sofia, Epelbaum, Jacques, Grouselle, Dominique, Boirie, Yves, Montaurier, Christophe, Cuenco, Joyceline, Minnion, James S., Thomas, Thierry, Mure, Sylvie, Hager, Jörg, Estour, Bruno, Gheldof, Nele, Germain, Natacha

“…Background Constitutional thinness (CT), a non‐malnourished underweight state with no eating disorders, is characterized by weight gain resistance to high fat…”
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Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study by Hess, Anne Lundby, Carayol, Jérôme, Blædel, Trine, Hager, Jörg, Di Cara, Alessandro, Astrup, Arne, Saris, Wim H M, Larsen, Lesli Hingstrup, Valsesia, Armand

“…Angiopoietin-like protein 3 (ANGPTL3), a liver-derived protein, plays an important role in the lipid and lipoprotein metabolism. Using data available from the…”
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Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism by Maussion, Gilles, Carayol, Jérôme, Lepagnol-Bestel, Aude-Marie, Tores, Frédéric, Loe-Mie, Yann, Milbreta, Ulla, Rousseau, Francis, Fontaine, Karine, Renaud, Julie, Moalic, Jean-Marie, Philippi, Anne, Chedotal, Alain, Gorwood, Philip, Ramoz, Nicolas, Hager, Jörg, Simonneau, Michel

“…Autism spectrum disorders (ASDs) are common, heritable, but genetically heterogeneous neurodevelopmental conditions. We recently defined a susceptibility locus…”
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