Search Results - "Carambia, Antonella"
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The aryl hydrocarbon receptor in liver inflammation
Published in Seminars in immunopathology (01-08-2021)“…The aryl hydrocarbon receptor (AHR) is a ubiquitously expressed ligand-activated transcription factor with multifaceted physiological functions. In the immune…”
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2
Microplastics detected in cirrhotic liver tissue
Published in EBioMedicine (01-08-2022)“…The contamination of ecosystem compartments by microplastics (MPs) is an ubiquitous problem. MPs have been observed in mice tissues, and recently in human…”
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3
Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis
Published in The Journal of immunology (1950) (15-03-2015)“…Autoimmune liver diseases predominantly affect women. In this study, we aimed to elucidate how sex affects autoimmune hepatic inflammation. Acute experimental…”
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4
CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis
Published in The Journal of immunology (1950) (01-05-2011)“…The chemokine receptor CXCR3 is preferentially expressed by Th1 cells and critically involved in their recruitment to inflamed tissue. In a mouse model of…”
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5
CD4+ T-cell help is required for effective CD8+ T cell-mediated resolution of acute viral hepatitis in mice
Published in PloS one (21-01-2014)“…Cytotoxic CD8+ T cells are essential for the control of viral liver infections, such as those caused by HBV or HCV. It is not entirely clear whether CD4+…”
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6
Failure of thymic deletion and instability of autoreactive Tregs drive autoimmunity in immune-privileged liver
Published in JCI insight (22-03-2021)“…The liver is an immune-privileged organ that can deactivate autoreactive T cells. Yet in autoimmune hepatitis (AIH), autoreactive T cells can defy hepatic…”
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7
Scavenger receptor CD36 mediates uptake of high density lipoproteins in mice and by cultured cells[S]
Published in Journal of lipid research (01-04-2011)“…The mechanisms of HDL-mediated cholesterol transport from peripheral tissues to the liver are incompletely defined. Here the function of scavenger receptor…”
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8
Dietary and metabolic modulators of hepatic immunity
Published in Seminars in immunopathology (01-02-2018)“…The liver is the central metabolic organ of the organism and is thus constantly exposed to gut-derived dietary and microbial antigens. The liver maintains…”
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9
Harnessing the liver to induce antigen-specific immune tolerance
Published in Seminars in immunopathology (01-07-2022)“…Autoimmune diseases develop when the adaptive immune system attacks the body’s own antigens leading to tissue damage. At least 80 different conditions are…”
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10
CD4 T cells in hepatic immune tolerance
Published in Journal of autoimmunity (01-02-2010)“…Abstract The liver features a unique immune microenvironment, which seems to favour immune tolerance, both locally and systemically. The hepatic…”
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11
Liver sinusoidal cells collecting MHC-I molecules: You can’t get enough of a good thing
Published in Journal of hepatology (01-09-2014)Get full text
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12
Deciphering the highway code for lymphocyte traffic along the gut – liver axis
Published in Journal of hepatology (01-06-2014)Get full text
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13
Autoimmune hepatitis: Possible triggers, potential treatments
Published in Journal of hepatology (01-08-2020)Get full text
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14
TGF-β-dependent induction of CD4+ CD25+ Foxp3+ Tregs by liver sinusoidal endothelial cells
Published in Journal of hepatology (01-09-2014)“…Background & Aims CD4+ CD25+ Foxp3+ regulatory T cells (Tregs) have a profound ability to control immune responses. We have previously shown that the liver is…”
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15
Th17 cells bound for the liver: Group tourists or private travellers?
Published in Journal of hepatology (01-11-2012)Get full text
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16
Let it B in viral hepatitis?
Published in Journal of hepatology (01-07-2011)Get full text
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IL‐6 trans‐signaling is essential for the development of hepatocellular carcinoma in mice
Published in Hepatology (Baltimore, Md.) (01-01-2017)“…Hepatocellular carcinoma (HCC) is one of the most frequent tumors worldwide with rising incidence. The inflammatory cytokine, interleukin‐6 (IL‐6), is a…”
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18
Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice
Published in Journal of hepatology (01-06-2015)“…Graphical abstract…”
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19
AS115 - Interferon-gamma and CTLA-4 drive liver-induced systemic CD4 T cell tolerance
Published in Journal of hepatology (01-08-2020)Get full text
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20
Interferon-gamma and CTLA-4 drive liver-induced systemic CD4 T cell tolerance
Published in Journal of hepatology (01-08-2020)Get full text
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