Search Results - "Caramazza, Domenica"
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Circulating Interleukin (IL)-8, IL-2R, IL-12, and IL-15 Levels Are Independently Prognostic in Primary Myelofibrosis: A Comprehensive Cytokine Profiling Study
Published in Journal of clinical oncology (01-04-2011)“…Abnormal cytokine expression accompanies myelofibrosis and might be a therapeutic target for Janus-associated kinase (JAK) inhibitor drugs. This study…”
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DIPSS Plus: A Refined Dynamic International Prognostic Scoring System for Primary Myelofibrosis That Incorporates Prognostic Information From Karyotype, Platelet Count, and Transfusion Status
Published in Journal of clinical oncology (01-02-2011)“…The Dynamic International Prognostic Scoring System (DIPSS) for primary myelofibrosis (PMF) uses five risk factors to predict survival: age older than 65…”
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JAK Inhibitor in CALR-Mutant Myelofibrosis
Published in The New England journal of medicine (20-03-2014)“…To the Editor: Janus kinase (JAK) inhibitors are new targeted therapies for myelofibrosis that reduce the palpable spleen size to 50% of the baseline…”
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Recurrence of immune thrombocytopenia at the time of SARS-CoV-2 infection
Published in Annals of hematology (01-08-2020)Get full text
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A prognostic model to predict survival in 867 World Health Organization–defined essential thrombocythemia at diagnosis: a study by the International Working Group on Myelofibrosis Research and Treatment
Published in Blood (09-08-2012)“…Diagnosis of essential thrombocythemia (ET) has been updated in the last World Health Organization (WHO) classification. We developed a prognostic model to…”
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Impact of ruxolitinib on the natural history of primary myelofibrosis: a comparison of the DIPSS and the COMFORT-2 cohorts
Published in Blood (20-03-2014)“…The international prognostic scoring system (IPSS) provides reliable risk assessment in patients with primary myelofibrosis (PMF). Recent clinical trials in…”
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Alternate use of thrombopoietin receptor agonists in adult primary immune thrombocytopenia patients: A retrospective collaborative survey from Italian hematology centers
Published in American journal of hematology (01-01-2018)“…Sequential use of the TPO‐RAs romiplostim and eltrombopag in ITP patients failing either agent was retrospectively evaluated to assess efficacy and impact of…”
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Predictors of greater than 80% 2-year mortality in primary myelofibrosis: a Mayo Clinic study of 884 karyotypically annotated patients
Published in Blood (27-10-2011)“…DIPSS-plus (the Dynamic International Prognostic Scoring System-plus) includes 8 risk factors for survival in primary myelofibrosis. In the present study of…”
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Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
Published in Research and practice in thrombosis and haemostasis (01-08-2023)“…•Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing.•Twenty-six Italian patients were treated with caplacizumab for an…”
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10
It is time to change thrombosis risk assessment for PV and ET?
Published in Best practice & research. Clinical haematology (01-06-2014)“…Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms to be diagnosed according to the WHO classification. Molecular…”
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PB2611: EVANS SYNDROME: DISEASE AWARENESS AND CLINICAL MANAGEMENT IN A NATION‐WIDE ITALIAN SURVEY
Published in HemaSphere (08-08-2023)Get full text
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Relapsing or refractory idiopathic thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: the role of rituximab
Published in Transfusion (Philadelphia, Pa.) (01-12-2010)“…Idiopathic thrombotic thrombocytopenic purpura–hemolytic uremic syndrome (TTP‐HUS) is a rare disease responsive to treatment with plasma exchange (PE) but with…”
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Chromosome 1 abnormalities in myeloid malignancies: a literature survey and karyotype-phenotype associations
Published in European journal of haematology (01-03-2010)“…Chromosome 1 is the largest human chromosome and contains over 1600 known genes and 1000 novel coding sequences or transcripts. It is, therefore, not…”
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Clinical Predictors of Outcome in MPN
Published in Hematology/oncology clinics of North America (01-10-2012)“…Myeloproliferative neoplasms include 3 diseases: polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). PV and ET are…”
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Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls
Published in Blood (09-08-2012)“…Ruxolitinib is JAK1/JAK2 inhibitor with established clinical benefit in myelofibrosis (MF). We analyzed long-term outcomes of 107 patients with intermediate-2…”
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New generation small-molecule inhibitors in myeloproliferative neoplasms
Published in Current opinion in hematology (01-03-2012)“…PURPOSE OF REVIEWMyeloproliferative neoplasms (MPNs) are diseases that carry the JAK2 (V617F) mutation in about 70% of the patients. The purpose of this review…”
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Prediction of thrombosis in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a study on 1258 patients
Published in Leukemia (01-10-2022)“…Patients with Philadelphia-negative myeloproliferative neoplasms are at high risk of thrombotic events (TEs). Predisposing factors have been identified in…”
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Evans syndrome: Disease awareness and clinical management in a nation‐wide ITP‐NET survey
Published in European journal of haematology (01-10-2024)“…Evans syndrome (ES) is rare and mostly treated on a “case‐by‐case” basis and no guidelines are available. With the aim of assessing disease awareness and…”
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Cerebral venous thrombosis and myeloproliferative neoplasms: Results from two large databases
Published in Thrombosis research (01-07-2014)“…Abstract Introduction Myeloproliferative neoplasms (MPNs) include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF)…”
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Myeloproliferative neoplasms: from JAK2 mutations discovery to JAK2 inhibitor therapies
Published in Oncotarget (01-06-2011)“…Most BCR-ABL1-negative myeloproliferative neoplasms (MPN) carry an activating JAK2 mutation. Approximately 96% of patients with polycythemia vera (PV) harbors…”
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