Search Results - "Caramés, B."

Defective chaperone-mediated autophagy is a hallmark of joint disease in patients with knee osteoarthritis by Lorenzo-Gómez, I., Nogueira-Recalde, U., García-Domínguez, C., Oreiro-Villar, N., Lotz, M., Pinto-Tasende, J.A., Blanco, F.J., Caramés, B.

“…Defects in autophagy contribute to joint aging and Osteoarthritis (OA). Identifying specific autophagy types could be useful for developing novel treatments…”
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Insulin decreases autophagy and leads to cartilage degradation by Ribeiro, M, López de Figueroa, P, Blanco, F.J, Mendes, A.F, Caramés, B

“…Summary Objective Autophagy, a key homeostasis mechanism, is defective in Osteoarthritis (OA) and Type 2 Diabetes (T2D). T2D has been proposed as a risk factor…”
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Autophagy in the pathogenesis of aging-related OA by Caramés, B

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Diabetes-accelerated Experimental Osteoarthritis is Prevented by Autophagy Activation by Ribeiro, Madalena, BS, López de Figueroa, Paloma, BS, Nogueira-Recalde, Uxía, BS, Centeno, Alberto, MD, Mendes, Alexandrina F., PhD, Blanco, Francisco J., MD, Caramés, Beatriz, PhD

“…Summary Objective Type 2 Diabetes (T2D) is a risk factor for Osteoarthritis (OA). Autophagy, an essential homeostasis mechanism in articular cartilage, is…”
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Compromised autophagy precedes meniscus degeneration and cartilage damage in mice by Meckes, J.K., Caramés, B., Olmer, M., Kiosses, W.B., Grogan, S.P., Lotz, M.K., D'Lima, D.D.

“…Autophagy is a cellular homeostasis mechanism that facilitates normal cell function and survival. Objectives of this study were to determine associations…”
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Palytoxin detection and quantification using the fluorescence polarization technique by Alfonso, A., Fernández-Araujo, A., Alfonso, C., Caramés, B., Tobio, A., Louzao, M.C., Vieytes, M.R., Botana, L.M.

“…Palytoxin (PLT) is a highly toxic nonpeptidic marine natural product, with a complex chemical structure. Its mechanism of action targets Na,K-ATPase…”
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Cytokines, tumor necrosis factor-α and interleukin-1β, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes by López-Armada, M.J., Caramés, B., Lires-Deán, M., Cillero-Pastor, B., Ruiz-Romero, C., Galdo, F., Blanco, F.J.

“…This study addresses the effects of tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) on cell death in human chondrocytes. Osteoarthritis (OA) human…”
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Differential effects of tumor necrosis factor-α and interleukin-1β on cell death in human articular chondrocytes by Caramés, B., Ph.D, López-Armada, M.J., Ph.D, Cillero-Pastor, B., B.S, Lires-Dean, M., B.S, Vaamonde, C., B.S, Galdo, F., M.D, Blanco, F.J., M.D

“…Summary Objective The death of chondrocytes by apoptosis is characteristic of degenerative joint diseases, such as osteoarthritis (OA). Tumor necrosis factor-α…”
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Mitochondrial activity is modulated by TNFα and IL-1β in normal human chondrocyte cells by López-Armada, M.J., Caramés, B., Martín, M.A., Cillero-Pastor, B., Lires-Dean, M., Fuentes-Boquete, I., Arenas, J., Blanco, F.J.

“…Pro-inflammatory cytokines play an important role in osteoarthritis (OA). In osteoarthritic cartilage, chondrocytes exhibit an alteration in mitochondrial…”
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Autophagy activation protects from mitochondrial dysfunction in human chondrocytes by Caramés, B, López de Figueroa, P, Lotz, M, Blanco, F.J

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Glucosamine regulates autophagy in vitro and in vivo by Caramés, B, Brinson, D, Lotz, M

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Anti-apoptotic effect of transforming growth factor-β1 on human articular chondrocytes: role of protein phosphatase 2A by Lires-Deán, M., B.S, Caramés, B., Ph.D, Cillero-Pastor, B., B.S, Galdo, F., M.D, López-Armada, M.J., Ph.D, Blanco, F.J., M.D., Ph.D

“…Summary Objective To study whether transforming growth factor-β1 (TGF-β1) is able to protect human chondrocytes from apoptosis and to analyze the role of…”
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The mammalian target of rapamycin regulates lipid metabolism in osteoarthritic human articular cartilage by Cillero-Pastor, B, López de Figueroa, P, Rocha, B, Filgueira-Fernandez, P, Goyanes, N, Heeren, R.A, Blanco, F.J, Caramés, B

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204 EXPRESSION PATTERNS AND FUNCTION OF CHROMATIN PROTEIN HMGB2 DURING MESENCHYMAL STEM CELL DIFFERENTIATION by Taniguchi, N, Caramés, B, Lotz, M

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207 INHIBITION OF MAMMALIAN TARGET OF RAPAMYCIN (mTOR) INDUCES AUTOPHAGY IN ARTICULAR CARTILAGE AND REDUCES SEVERITY OF EXPERIMENTAL OSTEOARTHRITIS by Caramés, B, Hasegawa, A, Taniguchi, N, Blanco, F, Terkeltaub, R, Lotz, M

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207 MECHANICAL INJURY SUPPRESSES AUTOPHAGY REGULATORS IN CARTIALGE SUPERFICIAL ZONE AND ITS PHARMACOLOGICAL ACTIVATION RESULTS IN CHONDROPROTECTION by Caramés, B, Taniguchi, N, Seino, D, Blanco, F, D'Lima, D, Lotz, M

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188 AUTOPHAGY IS A PROTECTIVE MECHANISM IN NORMAL CARTILAGE AND ITS AGING-RELATED LOSS IS LINKED WITH CELL DEATH AND OSTEOARTHRITIS by Caramés, B, Taniguchi, N, Otsuki, S, Blanco, F, Lotz, M

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Phosphatase-1 and -2A inhibition modulates apoptosis in human osteoarthritis chondrocytes independently of nitric oxide production by López-Armada, M J, Caramés, B, Cillero-Pastor, B, Lires-Deán, M, Maneiro, E, Fuentes, I, Ruíz, C, Galdo, F, Blanco, F J

“…Objective: To characterise the role of phosphatase-1 and -2A (PP1/2A) in the modulation of apoptosis in human osteoarthritis (OA) chondrocytes. Methods: Human…”
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232 CHONDROITIN SULFATE MODULATES THE MITOCHONDRIAL ACTIVITY OF HUMAN ARTICULAR CHONDROCYTES by Blanco, F.J, López-Armada, M.J, Cillero-Pastor, B, Caramés, B, Montell, E, Vergés, J, Galdo, F

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207 TUMOR NECROSIS FACTOR α BUT NOT INTERLEUKIN 1 β POTENCIATE CELL DEATH INDUCED BY Ro 31-8220, A PROTEIN KINASE INHIBITOR, IN NORMAL HUMAN ARTICULAR CHONDROCYTES by Caramés, B, López-Armada, M.J, Lires-Deán, M, Cillero-Pastor, B, Vaamonde, C, Lema, B, Galdo, F, Blanco, F.J

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