Search Results - "Carabia, Júlia"

Repolarization of tumor infiltrating macrophages and increased survival in mouse primary CNS lymphomas after XPO1 and BTK inhibition by Jiménez, Isabel, Carabia, Júlia, Bobillo, Sabela, Palacio, Carles, Abrisqueta, Pau, Pagès, Carlota, Nieto, Juan C., Castellví, Josep, Martínez-Ricarte, Francisco, Escoda, Lourdes, Perla, Cristóbal, Céspedes Torrez, Dennis H., Boix, Joan, Purroy, Noelia, Puigdefàbregas, Lluís, Seoane, Joan, Bosch, Francesc, Crespo, Marta

“…Background Patients diagnosed with primary central nervous system lymphoma (PCNSL) often face dismal outcomes due to the limited availability of therapeutic…”
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ZAP-70 promotes the infiltration of malignant B-lymphocytes into the bone marrow by enhancing signaling and migration after CXCR4 stimulation by Calpe, Eva, Purroy, Noelia, Carpio, Cecilia, Abrisqueta, Pau, Carabia, Júlia, Palacio, Carles, Castellví, Josep, Crespo, Marta, Bosch, Francesc

“…ZAP-70 in chronic lymphocytic leukemia (CLL) is associated with enhanced response to microenvironmental stimuli. We analyzed the functional consequences of…”
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Cell free circulating tumor DNA in cerebrospinal fluid detects and monitors central nervous system involvement of B-cell lymphomas by Bobillo, Sabela, Crespo, Marta, Escudero, Laura, Mayor, Regina, Raheja, Priyanka, Carpio, Cecilia, Rubio-Perez, Carlota, Tazón-Vega, Bárbara, Palacio, Carlos, Carabia, Júlia, Jiménez, Isabel, Nieto, Juan C, Montoro, Julia, Martínez-Ricarte, Francisco, Castellvi, Josep, Simó, Marc, Puigdefàbregas, Lluis, Abrisqueta, Pau, Bosch, Francesc, Seoane, Joan

“…The levels of cell free circulating tumor DNA (ctDNA) in plasma correlated with treatment response and outcome in systemic lymphomas. Notably, in brain tumors,…”
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Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the immune activation induced by previous nivolumab therapy by Nieto, Juan C., Roldán, Elisa, Jiménez, Isabel, Fox, Laura, Carabia, Júlia, Ortí, Guillermo, Puigdefàbregas, Lluís, Gallur, Laura, Iacoboni, Gloria, Raheja, Priyanka, Pérez, Ana, Bobillo, Sabela, Salamero, Olga, Palacio, Carlos, Valcárcel, David, Crespo, Marta, Bosch, Francesc, Barba, Pere

“…Patients receiving an allogeneic hematopoietic cell transplantation (allo-HCT) after the use of PD-1 inhibitors seem to be at a higher risk of developing acute…”
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Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo by Purroy, Noelia, Abrisqueta, Pau, Carabia, Júlia, Carpio, Cecilia, Palacio, Carles, Bosch, Francesc, Crespo, Marta

“…Chronic lymphocytic leukemia (CLL) cells residing in the bone marrow (BM) and in secondary lymphoid tissues receive survival and proliferative signals from the…”
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Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia by Carabia, Júlia, Carpio, Cecilia, Abrisqueta, Pau, Jiménez, Isabel, Purroy, Noelia, Calpe, Eva, Palacio, Carles, Bosch, Francesc, Crespo, Marta

“…Chronic lymphocytic leukemia (CLL) cells are highly dependent on microenvironment, being the BCR pathway one key player in this crosstalk. Among proteins…”
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Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells by Purroy, Noelia, Carabia, Júlia, Abrisqueta, Pau, Egia, Leire, Aguiló, Meritxell, Carpio, Cecilia, Palacio, Carles, Crespo, Marta, Bosch, Francesc

“…Proliferation and survival of chronic lymphocytic leukemia (CLL) cells depend on microenvironmental signals coming from lymphoid organs. One of the key players…”
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Immunological and genetic kinetics from diagnosis to clinical progression in chronic lymphocytic leukemia by Jiménez, Isabel, Tazón-Vega, Bárbara, Abrisqueta, Pau, Nieto, Juan C, Bobillo, Sabela, Palacio-García, Carles, Carabia, Júlia, Valdés-Mas, Rafael, Munuera, Magdalena, Puigdefàbregas, Lluís, Parra, Genís, Esteve-Codina, Anna, Franco-Jarava, Clara, Iacoboni, Gloria, Terol, María José, García-Marco, José Antonio, Crespo, Marta, Bosch, Francesc

“…Mechanisms driving the progression of chronic lymphocytic leukemia (CLL) from its early stages are not fully understood. The acquisition of molecular changes…”
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Abstract 5516: Immunological effects of SYK inhibition using TAK659 in patients diagnosed with diffuse large B cell lymphoma by Crespo, Marta, Nieto, Juan C., Hernández, Cristina, del Carmen Carpio, Cecilia, Jiménez, Isabel, Palacio, Carlos, Carabia, Júlia, Abrisqueta, Pau, Bosch, Francesc

“…Abstract Targeted inhibition of the BCR signaling pathway is a therapeutic option for patients diagnosed with Diffuse Large B-cell Lymphoma (DLBCL) currently…”
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Abstract 4568: Reversal of immune tolerance and increased anti tumoral immune response in a mouse model of CNS B cell lymphoma after combined XPO1 and BCR inhibition by Crespo, Marta, Jiménez, Isabel, Carabia, Júlia, Bobillo, Sabela, Abrisqueta, Pau, Palacio, Carles, Nieto, Juan Camilo, Boix, Joan, Carpio, Cecilia del Carmen, Castellví, Josep, Seoane, Joan, Bosch, Francesc

“…Abstract Primary CNS lymphoma (PCNSL) is an aggressive non-Hodgkin lymphoma usually classified as ABC-DLBCL. Selinexor inactivates XPO-1 protein and induces…”
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Xpo-1 Inhibition Synergizes with BCR Inhibition, Blocks Tumor Growth and Tumor-Associated Macrophages Infiltration and Prolongs Survival in a Bioluminescent Animal Model of Primary Central Nervous System Lymphoma by Crespo, Marta, Carabia, Júlia, Jiménez, Isabel, Bobillo, Sabela, Abrisqueta, Pau, Palacio, Carles, Nieto, Juan C, Boix, Joan, Carpio, Cecilia, Castellvi, Josep, Seoane, Joan, Bosch, Francesc

“…Primary central nervous system lymphoma (PCNSL) is an infrequent and aggressive non-Hodgkin lymphoma usually classified as diffuse large B-cell lymphoma…”
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Graft-Versus-Host Disease (GVHD) Prophylaxis with Post-Transplant Cyclophosphamide (PTCY) Induces a More Tolerant Immune Response after Allogeneic Hematopoietic Cell Transplantation (Allo-HCT) in Patients Previously Exposed to Nivolumab by Nieto, Juan C, Roldan, Elisa, Jiménez, Isabel, Fox, Laura, Carabia, Júlia, Orti, Guillermo, Puigdefàbregas, Lluis, Gallur, Laura, Iacoboni, Gloria, Raheja, Priyanka, Perez, Ana, Salamero, Olga, Palacio, Carlos, Valcarcel, David, Crespo, Marta, Bosch, Francesc, Barba, Pere

“…Allo-HCT has been shown to be feasible in patients previously exposed to anti-PD-1 monoclonal antibodies, albeit their use has been associated with a more…”
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Syk Inhibition By TAK-659 Overcomes Proliferative, Survival and Migratory Signals from the Microenvironment in Chronic Lymphocytic Leukemia Cells by Purroy, Noelia, Abrisqueta, Pau, Carabia, Júlia, Calpe, Eva, Carpio, Cecilia, Palacio, Carles, Crespo, Marta, Bosch, Francesc

“…Chronic lymphocytic leukemia (CLL) is characterized by the accumulation and proliferation of monoclonal CD5+ mature B cells in peripheral blood, lymph nodes…”
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Microrna Mir-21 Is Upregulated after Different Microenvironmental Stimuli and Controls Proliferation, Chemotaxis and Chemoresistance in Chronic Lymphocytic Leukemia by Crespo, Marta, Carabia, Júlia, Purroy, Noelia, Carpio, Cecilia, Abrisqueta, Pau, Palacio, Carles, Bosch, Francesc

“…Aberrant expression of diverse microRNAs (miRNAs) has been related to pathogenesis and clinical outcome in patients with CLL. miR-21 is overexpressed in a wide…”
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Clinical Progression of Chronic Lymphocytic Leukemia (CLL) Is Characterized By a Progressive Increase of the Exhausted T-Cell Phenotype and Immunosuppression Induced By Leukemic Cells by Jiménez, Isabel, Bobillo, Sabela, Abrisqueta, Pau, Tazón, Bárbara, Palacio, Carles, Nieto, Juan C, Carabia, Júlia, Terol, Maria Jose, Garcia-Marco, Jose, Boix, Joan, Munuera, Magdalena, Puigdefàbregas, Lluis, Roldán, Elisa, Crespo, Marta, Bosch, Francesc

“…The mechanisms leading to clinical progression of CLL from early asymptomatic stages are not fully elucidated, being the acquisition of molecular alterations…”
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Regulation Of Microrna Mir-21 Expression By ZAP-70 Protein In Chronic Lymphocytic Leukemia by Crespo, Marta, Carpio, Cecilia, Carabia, Júlia, Abrisqueta, Pau, Calpe, Eva, Purroy, Noelia, Palacio, Carles, Bosch, Francesc

“…Aberrant expression of diverse microRNAs (miRNAs) has been related to pathogenesis and clinical outcome in patients with CLL. In this regard, miR-21 expression…”
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XPO1 Inhibition By Selinexor Synergizes with BCR Inhibition, Blocks Tumor Growth and Prolongs Survival in a Bioluminescent Animal Model of Primary Central Nervous System Lymphoma by Crespo, Marta, Carabia, Julia, Jiménez, Isabel, Bobillo, Sabela, Abrisqueta, Pau, Palacio, Carles, Carpio, Cecilia, Castellvi, Josep, Purroy, Noelia, Seoane, Joan, Bosch, Francesc

“…Primary central nervous system lymphoma (PCNSL) is a very aggressive non-Hodgkin lymphoma localized in the cerebral parenchyma, eyes, leptomeninges or spinal…”
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Effect of syk inhibition by TAK659 on proliferative, survival, and migratory signals from the microenvironment in chronic lymphocytic leukemia by Purroy, Noelia, Abrisqueta, Pau, Carabia, Julia, Calpe, Eva, Carpio, Cecilia, Palacio, Carles, Crespo, Marta, Bosch, Francesc

“…Abstract only…”
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A gene expression assay based on chronic lymphocytic leukemia activation in the microenvironment to predict progression by Abrisqueta, Pau, Medina, Daniel, Villacampa, Guillermo, Lu, Junyan, Alcoceba, Miguel, Carabia, Julia, Boix, Joan, Tazón-Vega, Barbara, Iacoboni, Gloria, Bobillo, Sabela, Marín-Niebla, Ana, González, Marcos, Zenz, Thorsten, Crespo, Marta, Bosch, Francesc

“…•The CLL15 signature, based on the expression of genes associated with microenvironment signaling, predicts early progression in CLL.•The predictive power of…”
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ZAP-70 Promotes the Infiltration of Malignant B-Lymphocytes into the Bone Marrow by Enhancing Signaling and Migration after CXCR4 Stimulation: e81221 by Calpe, Eva, Purroy, Noelia, Carpio, Cecilia, Abrisqueta, Pau, Carabia, Julia, Palacio, Carles, Castellvi, Josep, Crespo, Marta, Bosch, Francesc

“…ZAP-70 in chronic lymphocytic leukemia (CLL) is associated with enhanced response to microenvironmental stimuli. We analyzed the functional consequences of…”
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