Search Results - "Caputo, S"

Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting by Rotolo, Antonia, Caputo, Valentina S., Holubova, Monika, Baxan, Nicoleta, Dubois, Olivier, Chaudhry, Mohammed Suhail, Xiao, Xiaolin, Goudevenou, Katerina, Pitcher, David S., Petevi, Kyriaki, Kachramanoglou, Carolina, Iles, Sandra, Naresh, Kikkeri, Maher, John, Karadimitris, Anastasios

“…Chimeric antigen receptor anti-CD19 (CAR19)-T cell immunotherapy-induced clinical remissions in CD19+ B cell lymphomas are often short lived. We tested whether…”
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Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways by Psaila, Bethan, Barkas, Nikolaos, Iskander, Deena, Roy, Anindita, Anderson, Stacie, Ashley, Neil, Caputo, Valentina S, Lichtenberg, Jens, Loaiza, Sandra, Bodine, David M, Karadimitris, Anastasios, Mead, Adam J, Roberts, Irene

“…Recent advances in single-cell techniques have provided the opportunity to finely dissect cellular heterogeneity within populations previously defined by…”
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Analysis of a HT-PEMFC range extender for a light duty full electric vehicle (LD-FEV) by Millo, F., Caputo, S., Piu, A.

“…The usage of a Fuel Cell (FC) as a range extender in a Full Electric Vehicle (FEV) is a convenient solution to address the issue of the shortage of range of…”
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Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma by Alvarez-Benayas, Jaime, Trasanidis, Nikolaos, Katsarou, Alexia, Ponnusamy, Kanagaraju, Chaidos, Aristeidis, May, Philippa C., Xiao, Xiaolin, Bua, Marco, Atta, Maria, Roberts, Irene A. G., Auner, Holger W., Hatjiharissi, Evdoxia, Papaioannou, Maria, Caputo, Valentina S., Sudbery, Ian M., Karadimitris, Anastasios

“…Multiple myeloma is a genetically heterogeneous cancer of the bone marrow plasma cells (PC). Distinct myeloma transcriptome profiles are primarily driven by…”
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The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma by Ponnusamy, Kanagaraju, Tzioni, Maria Myrsini, Begum, Murshida, Robinson, Mark E, Caputo, Valentina S, Katsarou, Alexia, Trasanidis, Nikolaos, Xiao, Xiaolin, Kostopoulos, Ioannis V, Iskander, Deena, Roberts, Irene, Trivedi, Pritesh, Auner, Holger W, Naresh, Kikkeri, Chaidos, Aristeidis, Karadimitris, Anastasios

“…Multiple myeloma is a malignancy of plasma cells initiated and driven by primary and secondary genetic events. However, myeloma plasma cell survival and…”
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Weight Beneficial Treatments for Type 2 Diabetes by Meneghini, L. F, Orozco-Beltran, D, Khunti, K, Caputo, S, Damçi, T, Liebl, A, Ross, S. A

“…Context: The close link between type 2 diabetes and excess body weight highlights the need to consider the weight effects of different treatment regimens. We…”
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Role of Polymorphisms of NKG2D Receptor and Its Ligands in Acute Myeloid Leukemia and Human Stem Cell Transplantation by Machuldova, Alena, Holubova, Monika, Caputo, Valentina S, Cedikova, Miroslava, Jindra, Pavel, Houdova, Lucie, Pitule, Pavel

“…Natural killer cells possess key regulatory function in various malignant diseases, including acute myeloid leukemia. NK cell activity is driven by signals…”
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Peculiar clinical presentation of COVID-19 and predictors of mortality in the elderly: A multicentre retrospective cohort study by Bavaro, D.F., Diella, L., Fabrizio, C., Sulpasso, R., Bottalico, I.F., Calamo, A., Santoro, C.R., Brindicci, G., Bruno, G., Mastroianni, A., Buccoliero, G.B., Carbonara, S., Lo Caputo, S., Santantonio, T., Monno, L., Angarano, G., Saracino, A.

“…•Frail elderly COVID-19 patients showed frequent extrapulmonary signs and symptoms.•Frailty, dehydration and mechanical ventilation predicted mortality in the…”
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Assessment of the functional impact of germline BRCA1/2 variants located in non-coding regions in families with breast and/or ovarian cancer predisposition by dos Santos, E. Santana, Caputo, S. M., Castera, L., Gendrot, M., Briaux, A., Breault, M., Krieger, S., Rogan, P. K., Mucaki, E. J., Burke, L. J., Bièche, I., Houdayer, C., Vaur, D., Stoppa-Lyonnet, D., Brown, M. A., Lallemand, F., Rouleau, E.

“…Purpose The molecular mechanism of breast and/or ovarian cancer susceptibility remains unclear in the majority of patients. While germline mutations in the…”
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Factors influencing the normalization of CD4+ T-cell count, percentage and CD4+/CD8+ T-cell ratio in HIV-infected patients on long-term suppressive antiretroviral therapy by Torti, C., Prosperi, M., Motta, D., Digiambenedetto, S., Maggiolo, F., Paraninfo, G., Ripamonti, D., Cologni, G., Fabbiani, M., Caputo, S.L., Sighinolfi, L., Ladisa, N., El-Hamad, I., Quiros-Roldan, E., Frank, I.

“…We evaluated factors associated with normalization of the absolute CD4+ T-cell counts, per cent CD4+ T cells and CD4+/CD8+ T-cell ratio. A multicentre…”
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Natural SARS-CoV-2 Infection Affects Neutralizing Activity in Saliva of Vaccinees by Garziano, Micaela, Utyro, Olga, Poliseno, Mariacristina, Santantonio, Teresa Antonia, Saulle, Irma, Strizzi, Sergio, Lo Caputo, Sergio, Clerici, Mario, Introini, Andrea, Biasin, Mara

“…SARS-CoV-2 transmission mainly occurs through exposure of the upper airway mucosa to infected secretions such as saliva, which are excreted by an infected…”
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Effect of carbohydrate counting and medical nutritional therapy on glycaemic control in Type 1 diabetic subjects: a pilot study by Scavone, G., Manto, A., Pitocco, D., Gagliardi, L., Caputo, S., Mancini, L., Zaccardi, F., Ghirlanda, G.

“…Diabet. Med. 27, 477–479 (2010) Aims  The effect of a balanced, carbohydrate‐counting diet on glycaemic control in Type 1diabetic subjects is unclear. Our aim…”
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Improving the Clinical Application of Natural Killer Cells by Modulating Signals Signal from Target Cells by Holubova, Monika, Leba, Martin, Gmucova, Hana, Caputo, Valentina S, Jindra, Pavel, Lysak, Daniel

“…Relapsed acute myeloid leukemia (AML) is a significant post-transplant complication lacking standard treatment and associated with a poor prognosis. Cellular…”
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Diabetes and severity of COVID-19: What is the link? by Pitocco, D., Viti, L., Tartaglione, L., Di Leo, M., Rizzo, G.E., Manto, A., Rizzi, A., Caputo, S., Pontecorvi, A.

“…In Diabetes Mellitus the loss of capacity to regulate immunity, the reduction of pulmonary functions and the pro-thrombotic state determine the severity of…”
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Association of complement receptor 2 polymorphisms with innate resistance to HIV-1 infection by Herrero, R, Real, L M, Rivero-Juárez, A, Pineda, J A, Camacho, Á, Macías, J, Laplana, M, Konieczny, P, Márquez, F J, Souto, J C, Soria, J M, Saulle, I, Lo Caputo, S, Biasin, M, Rivero, A, Fibla, J, Caruz, A

“…HIV-1 induces activation of complement through the classical and lectin pathways. However, the virus incorporates several membrane-bound or soluble regulators…”
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Breast and ovarian cancer predisposition due to de novo BRCA1 and BRCA2 mutations by Golmard, L, Delnatte, C, Laugé, A, Moncoutier, V, Lefol, C, Abidallah, K, Tenreiro, H, Copigny, F, Giraudeau, M, Guy, C, Barbaroux, C, Amorim, G, Briaux, A, Guibert, V, Tarabeux, J, Caputo, S, Collet, A, Gesta, P, Ingster, O, Stern, M-H, Rouleau, E, de Pauw, A, Gauthier-Villars, M, Buecher, B, Bézieau, S, Stoppa-Lyonnet, D, Houdayer, C

“…BRCA1 and BRCA2 are the two major genes predisposing to breast and ovarian cancer. Whereas high de novo mutation rates have been demonstrated for several…”
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Two nasal swabs may not be enough to exclude SARS-CoV-2 infection in symptomatic patients by Fiore, J R, D'Errico, M, Bottalico, I, Rizzo, M, Montemurro, L, Lo Caputo, S, Faleo, G, Di Stefano, M, Santantonio, T

“…The spread of COVID-19 (COronaVIrus Disease 2019), due to SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus 2) has taken on dramatic pandemic…”
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Reduced community viral load does not coincide with a reduction in the rate of new HIV diagnoses and recent infections: data from a region of southern Italy by Monno, L, Saracino, A, Scudeller, L, Santoro, C, Brindicci, G, Punzi, G, Lagioia, A, Lo Caputo, S, Angarano, G

“…Objectives We assessed whether changes in community viral load (CVL) over time were associated with the rate of new HIV diagnoses (NDs). Methods HIV‐1‐positive…”
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Brd2/4 and Myc regulate alternative cell lineage programmes during early osteoclast differentiation in vitro by Caputo, Valentina S., Trasanidis, Nikolaos, Xiao, Xiaolin, Robinson, Mark E., Katsarou, Alexia, Ponnusamy, Kanagaraju, Prinjha, Rab K., Smithers, Nicholas, Chaidos, Aristeidis, Auner, Holger W., Karadimitris, Anastasios

“…Osteoclast (OC) development in response to nuclear factor kappa-Β ligand (RANKL) is critical for bone homeostasis in health and in disease. The early and…”
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The safety and efficacy of adding once-daily insulin detemir to oral hypoglycaemic agents in patients with type 2 diabetes in a clinical practice setting in 10 countries by Khunti, K., Caputo, S., Damci, T., Dzida, G. J., Ji, Q., Kaiser, M., Karnieli, E., Liebl, A., Ligthelm, R. J., Nazeri, A., Orozco-Beltran, D., Pan, C., Ross, S. A., Svendsen, A. L., Vora, J., Yale, J.-F., Meneghini, L. F.

“…Aims Evaluate the safety and efficacy of once‐daily insulin detemir initiated in routine clinical practice in patients with type 2 diabetes mellitus…”
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