Search Results - "Caputi, Francesca Felicia"

Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy by Carboni, Lucia, Rullo, Laura, Caputi, Francesca Felicia, Stamatakos, Serena, Candeletti, Sanzio, Romualdi, Patrizia

“…Trazodone is an efficacious atypical antidepressant acting both as an SSRI and a 5HT2A and 5HT2C antagonist. Antagonism to H1-histaminergic and…”
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Effects of Different Opioid Drugs on Oxidative Status and Proteasome Activity in SH-SY5Y Cells by Rullo, Laura, Caputi, Francesca Felicia, Losapio, Loredana Maria, Morosini, Camilla, Posa, Luca, Canistro, Donatella, Vivarelli, Fabio, Romualdi, Patrizia, Candeletti, Sanzio

“…Opioids are the most effective drugs used for the management of moderate to severe pain; however, their chronic use is often associated with numerous adverse…”
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Interplay between Prokineticins and Histone Demethylase KDM6A in a Murine Model of Bortezomib-Induced Neuropathy by Rullo, Laura, Franchi, Silvia, Amodeo, Giada, Caputi, Francesca Felicia, Verduci, Benedetta, Losapio, Loredana Maria, Sacerdote, Paola, Romualdi, Patrizia, Candeletti, Sanzio

“…Chemotherapy-induced neuropathy (CIN) is a major adverse effect associated with many chemotherapeutics, including bortezomib (BTZ). Several mechanisms are…”
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Dysregulation of Nociceptin/Orphanin FQ and Dynorphin Systems in the Extended Amygdala of Alcohol Preferring Marchigian Sardinian (msP) Rats by Caputi, Francesca Felicia, Stopponi, Serena, Rullo, Laura, Palmisano, Martina, Ubaldi, Massimo, Candeletti, Sanzio, Ciccocioppo, Roberto, Romualdi, Patrizia

“…Previous studies have shown that genetically selected Marchigian Sardinian alcohol-preferring (msP) rats consume excessive amounts of ethanol to self-medicate…”
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Interplay between the Endogenous Opioid System and Proteasome Complex: Beyond Signaling by Caputi, Francesca Felicia, Rullo, Laura, Stamatakos, Serena, Candeletti, Sanzio, Romualdi, Patrizia

“…Intracellular signaling mechanisms underlying the opioid system regulation of nociception, neurotransmitters release, stress responses, depression, and the…”
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An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia by Caputi, Francesca Felicia, Carboni, Lucia, Rullo, Laura, Alessandrini, Irene, Balzani, Eleonora, Melotti, Rita Maria, Romualdi, Patrizia, Candeletti, Sanzio, Fanelli, Andrea

“…This study aimed to investigate DNA methylation levels in patients undergoing major breast surgery under opioid-based general anesthesia. Blood samples were…”
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Modulation of the Negative Affective Dimension of Pain: Focus on Selected Neuropeptidergic System Contributions by Caputi, Francesca Felicia, Rullo, Laura, Stamatakos, Serena, Candeletti, Sanzio, Romualdi, Patrizia

“…It is well known that emotions can interfere with the perception of physical pain, as well as with the development and maintenance of painful conditions. On…”
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Safe Use of Opioids in Chronic Kidney Disease and Hemodialysis Patients: Tips and Tricks for Non-Pain Specialists by Coluzzi, Flaminia, Caputi, Francesca Felicia, Billeci, Domenico, Pastore, Antonio Luigi, Candeletti, Sanzio, Rocco, Monica, Romualdi, Patrizia

“…In patients suffering from moderate-to-severe chronic kidney disease (CKD) or end-stage renal disease (ESRD), subjected to hemodialysis (HD), pain is very…”
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Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences by Costa, Giulia, Caputi, Francesca Felicia, Serra, Marcello, Simola, Nicola, Rullo, Laura, Stamatakos, Serena, Sanna, Fabrizio, Germain, Marc, Martinoli, Maria-Grazia, Candeletti, Sanzio, Morelli, Micaela, Romualdi, Patrizia

“…3,4-Methylenedioxymethamphetamine (MDMA, “ecstasy”) is an amphetamine-related drug that may damage the dopaminergic nigrostriatal system. To investigate the…”
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The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells by Caputi, Francesca Felicia, Acquas, Elio, Kasture, Sanjay, Ruiu, Stefania, Candeletti, Sanzio, Romualdi, Patrizia

“…Behavioral studies demonstrated that the administration of Withania somnifera Dunal roots extract (WSE), prolongs morphine-elicited analgesia and reduces the…”
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A role for epigenetic mechanisms in the regulation of prodynorphin expression by alcohol by D’Addario, Claudio, Felicia Caputi, Francesca, Candeletti, Sanzio, Ove Ogren, Sven, Terenius, Lars, Ekstrom, Tomas, Maccarrone, Mauro, Romualdi, Patrizia

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Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission by Domi, Esi, Caputi, Francesca Felicia, Romualdi, Patrizia, Domi, Ana, Scuppa, Giulia, Candeletti, Sanzio, Atkins, Alison, Heilig, Markus, Demopulos, Gregory, Gaitanaris, George, Ciccocioppo, Roberto, Ubaldi, Massimo

“…An isoform of peroxisome proliferator-activated receptors (PPARs), PPARγ, is the receptor for the thiazolidinedione class of anti-diabetic medications…”
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Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine by Caputi, Francesca Felicia, Rullo, Laura, Acquas, Elio, Ciccocioppo, Roberto, Candeletti, Sanzio, Romualdi, Patrizia

“…[Display omitted] Notwithstanding the experimental evidence indicating Withania somnifera Dunal roots extract (WSE) ability to prolong morphine-elicited…”
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The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms by Caputi, Francesca Felicia, Di Cesare Mannelli, Lorenzo, Rullo, Laura, Micheli, Laura, Stamatakos, Serena, Posa, Luca, Ghelardini, Carla, Romualdi, Patrizia, Candeletti, Sanzio

“…[Display omitted] Oxaliplatin-induced neuropathy (OXAIN) is a major adverse effect of this antineoplastic drug, widely used in the treatment of colorectal…”
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Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure by Caputi, Francesca Felicia, Palmisano, Martina, Carboni, Lucia, Candeletti, Sanzio, Romualdi, Patrizia

“…[Display omitted] The recreational drug of abuse 3,4-methylenedioxymethamphetamine (MDMA) has been shown to produce neurotoxic damage and long-lasting changes…”
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Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens by Caputi, Francesca Felicia, Caffino, Lucia, Candeletti, Sanzio, Fumagalli, Fabio, Romualdi, Patrizia

“…•Adolescent cocaine exposure evokes neurochemical changes after short-term withdrawal.•Cocaine increases the pDYN gene expression in the NAc of early abstinent…”
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Nociceptive behavior and central neuropeptidergic dysregulations in male and female mice of a Fabry disease animal model by Rullo, Laura, Posa, Luca, Caputi, Francesca Felicia, Stamatakos, Serena, Formaggio, Francesco, Caprini, Marco, Liguori, Rocco, Candeletti, Sanzio, Romualdi, Patrizia

“…•The FD murine model displays sex differences in nociceptive behavior.•α-Gal-A KO mice exhibit sex-related neuropeptidergic gene expression…”
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NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area by Borruto, Anna Maria, Fotio, Yannick, Stopponi, Serena, Brunori, Gloria, Petrella, Michele, Caputi, Francesca Felicia, Romualdi, Patrizia, Candeletti, Sanzio, Narendran, Rajesh, Rorick‐Kehn, Linda M., Ubaldi, Massimo, Weiss, Friedbert, Ciccocioppo, Roberto

“…Background and Purpose Nociceptin/orphanin FQ (N/OFQ) peptide and its cognate receptor (NOP) are widely expressed in mesolimbic brain regions where they play…”
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Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1/MT2 receptor knockout mice by Posa, Luca, Lopez‐Canul, Martha, Rullo, Laura, De Gregorio, Danilo, Dominguez‐Lopez, Sergio, Kaba Aboud, Matthew, Caputi, Francesca Felicia, Candeletti, Sanzio, Romualdi, Patrizia, Gobbi, Gabriella

“…Melatonin, a neurohormone that binds to two G protein‐coupled receptors MT1 and MT2, is involved in pain regulation, but the distinct role of each receptor has…”
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Cocaine and ethanol target 26 S proteasome activity and gene expression in neuroblastoma cells by Caputi, Francesca Felicia, Carboni, Lucia, Mazza, Daria, Candeletti, Sanzio, Romualdi, Patrizia

“…Graphical abstract…”
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