Search Results - "Caputi, AP"
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Assessing the risk of osteonecrosis of the jaw due to bisphosphonate therapy in the secondary prevention of osteoporotic fractures
Published in Osteoporosis international (01-02-2013)“…Summary There is evidence that the use oral bisphosphonates can lead to osteronecrosis of the jaws (ONJ). Although the occurrence of ONJ appears rare among…”
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Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury
Published in Pharmacological reviews (01-03-2001)“…A vast amount of circumstantial evidence implicates oxygen-derived free radicals (especially superoxide and hydroxyl radical) and high-energy oxidants (such as…”
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Costs of Adding Sitagliptin or Sulphonylurea To Metformin: An Observational Study Using Administrative Database of Italy
Published in Value in health (01-10-2017)“…OBJECTIVES: To compare health-care costs of diabetic patients who start treatment with Sitagliptin (SITA) or Sulphonylurea (SUL), using Health Information…”
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PDB24 - Costs of Adding Sitagliptin or Sulphonylurea To Metformin: An Observational Study Using Administrative Database of Italy
Published in Value in health (01-10-2017)Get full text
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Cardiovascular and Gastrointestinal Safety of NSAIDs: A Systematic Review of Meta-Analyses of Randomized Clinical Trials
Published in Clinical pharmacology and therapeutics (01-06-2011)“…As part of the Safety of Non‐Steroidal Anti‐Inflammatory Drugs (SOS) Project, we reviewed the incidence of cardiovascular (CV) and gastrointestinal (GI) events…”
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Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population
Published in Pharmacological research (01-08-2004)“…The polymorphic cytochrome P450 isoenzymes (CYPs) 2C9, 2C19 and 2D6 metabolise many important drugs, as well as other xenobiotics. Their polymorphism gives…”
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PGI12 - Hepatitis C Treatment with First-Generation Protease Inhibitors in A Real-World Cohort: Risk-Benefit Profile and Costs of the Therapy
Published in Value in health (01-11-2016)Get full text
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Hepatitis C Treatment with First-Generation Protease Inhibitors in A Real-World Cohort: Risk-Benefit Profile and Costs of the Therapy
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Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-γ, reduces acute inflammation
Published in European journal of pharmacology (2004)“…Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors that are…”
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Adverse drug reactions related to amoxicillin alone and in association with clavulanic acid: data from spontaneous reporting in Italy
Published in Journal of antimicrobial chemotherapy (01-07-2007)“…Objectives To analyse an Italian database of spontaneous reporting of suspected adverse drug reactions in order to compare the safety profile of amoxicillin…”
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A role for superoxide in gentamicin-mediated nephropathy in rats
Published in European journal of pharmacology (16-08-2002)“…Gentamicin is an antibiotic effective against Gram-negative infection, whose clinical use is limited by its nephrotoxicity. Oxygen free radicals are considered…”
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Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation
Published in British journal of pharmacology (01-01-2002)“…The nuclear factor‐κB (NF‐κB) is a transcription factor which plays a pivotal role in the induction of genes involved in physiological processes as well as in…”
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Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway
Published in Cardiovascular research (01-08-2004)“…Several melanocortin peptides have a prompt and sustained resuscitating effect in conditions of hemorrhagic shock. The transcription nuclear factor kappaB…”
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Prescribing pattern of anti‐epileptic drugs in an Italian setting of elderly outpatients: a population‐based study during 2004–07
Published in British journal of clinical pharmacology (01-10-2010)“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • In the last years there has been a growing trend in anti‐epileptic drug (AED) use, particularly in elderly patients,…”
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The effect of the phytoestrogen genistein on plasma nitric oxide concentrations, endothelin-1 levels and endothelium dependent vasodilation in postmenopausal women
Published in Atherosclerosis (01-08-2002)“…The phytoestrogen genistein improves endothelial dysfunction in ovariectomized rats through a nitric oxide-dependent mechanism. We investigated whether…”
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Role of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-α) in the development of inflammatory bowel disease in mice
Published in Laboratory investigation (01-12-2004)“…The peroxisome proliferator-activated receptor-α (PPAR-α) is a member of the nuclear receptor superfamily of ligand-dependent transcription factors related to…”
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Glycogen synthase kinase-3 beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse
Published in Clinical Immunology (01-07-2006)“…Recently, glycogen synthase kinase-3 (GSK-3) has being identified as an ubiquitous serine-threonine protein kinase that participates in a multitude of cellular…”
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Protective effects of cyanidin-3- O-glucoside from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure
Published in Life sciences (1973) (18-07-2003)“…Anthocyanins are a group of naturally occurring phenolic compounds as colorants in several plants, flowers and fruits. These pigments have a great importance…”
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