Search Results - "Caproni, Lisa J."

A Comparison of Red Fluorescent Proteins to Model DNA Vaccine Expression by Whole Animal In Vivo Imaging by Kinnear, Ekaterina, Caproni, Lisa J, Tregoning, John S

“…DNA vaccines can be manufactured cheaply, easily and rapidly and have performed well in pre-clinical animal studies. However, clinical trials have so far been…”
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Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors by Thornton, Christopher D., Fielding, Stuart, Karbowniczek, Kinga, Roig-Merino, Alicia, Burrows, Alysha E., FitzPatrick, Lorna M., Sharaireh, Aseel, Tite, John P., Mole, Sara E., Harbottle, Richard P., Caproni, Lisa J., McKay, Tristan R.

“…The application of induced pluripotent stem cells (iPSCs) in advanced therapies is increasing at pace, but concerns remain over their clinical safety profile…”
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Production of lentiviral vectors using novel, enzymatically produced, linear DNA by Karda, Rajvinder, Counsell, John R., Karbowniczek, Kinga, Caproni, Lisa J., Tite, John P., Waddington, Simon N.

“…The manufacture of large quantities of high-quality DNA is a major bottleneck in the production of viral vectors for gene therapy. Touchlight Genetics has…”
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Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model by Allen, Alex, Wang, Chuan, Caproni, Lisa J., Sugiyarto, Gessa, Harden, Elena, Douglas, Leon R., Duriez, Patrick J., Karbowniczek, Kinga, Extance, Jon, Rothwell, Paul J., Orefo, Ifeayinwa, Tite, John P., Stevenson, Freda K., Ottensmeier, Christian H., Savelyeva, Natalia

“…Vaccination with DNA that encodes cancer antigens is a simple and convenient way to raise immunity against cancer and has already shown promise in the clinical…”
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Novel synthetic plasmid and Doggybone™ DNA vaccines induce neutralizing antibodies and provide protection from lethal influenza challenge in mice by Scott, Veronica L, Patel, Ami, Villarreal, Daniel O, Hensley, Scott E, Ragwan, Edwin, Yan, Jian, Sardesai, Niranjan Y, Rothwell, Paul J, Extance, Jonathan P, Caproni, Lisa J, Weiner, David B

“…Nucleic acid-based vaccines (NAVs) are a promising alternative to conventional influenza vaccines with the potential to increase influenza vaccine availability…”
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Optimizing a linear 'Doggybone' DNA vaccine for influenza virus through the incorporation of DNA targeting sequences and neuraminidase antigen by Cunliffe, Robert F, Stirling, David C, Razzano, Ilaria, Murugaiah, Valarmathy, Montomoli, Emanuele, Kim, Sungwon, Wane, Madina, Horton, Helen, Caproni, Lisa J, Tregoning, John S

“…Influenza virus represents a challenge for traditional vaccine approaches due to its seasonal changes and potential for zoonotic transmission. Nucleic acid…”
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Comparative analysis of enzymatically produced novel linear DNA constructs with plasmids for use as DNA vaccines by Walters, A A, Kinnear, E, Shattock, R J, McDonald, J U, Caproni, L J, Porter, N, Tregoning, J S

“…The use of DNA to deliver vaccine antigens offers many advantages, including ease of manufacture and cost. However, most DNA vaccines are plasmids and must be…”
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Antibiotics and clostridium difficile by Caproni, Lisa J

“…The aims of this thesis were to investigate the antibiotic susceptibility patterns of C. difficile with relation to the S-type of the isolates over a period of…”
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