Search Results - "Caprioli, Antonio"

Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety by Marco, Eva M, Rapino, Cinzia, Caprioli, Antonio, Borsini, Franco, Laviola, Giovanni, Maccarrone, Mauro

“…Anxiety disorders are among the most prevalent psychiatric diseases with high personal costs and a remarkable socio-economic burden. However, current treatment…”
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The spontaneously hypertensive-rat as an animal model of ADHD: evidence for impulsive and non-impulsive subpopulations by Adriani, Walter, Caprioli, Antonio, Granstrem, Oleg, Carli, Mirjana, Laviola, Giovanni

“…Attention-deficit hyperactivity disorder (ADHD) is a neuropsychiatric syndrome, affecting human infants and adolescents. Two main behavioural features are…”
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Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer’s disease by Ognibene, Elisa, Middei, Silvia, Daniele, Stefania, Adriani, Walter, Ghirardi, Orlando, Caprioli, Antonio, Laviola, Giovanni

“…Transgenic mouse models of Alzheimer’s disease (AD) have been recently advanced. Tg2576 mice have been shown to develop progressive β-amyloid (Aβ) neuritic…”
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Olanzapine (LY170053, 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine), but not the novel atypical antipsychotic ST2472 (9-piperazin-1-ylpyrrolo[2,1-b][1,3]benzothiazepine), chronic administration induces weight gain, hyperphagia, and metabolic dysregulation in mice by Coccurello, Roberto, Caprioli, Antonio, Conti, Roberto, Ghirardi, Orlando, Borsini, Franco, Carminati, Paolo, Moles, Anna

“…A mouse model of atypical antipsychotic-associated adverse effects was used to compare the liability to induce weight gain, food intake, and metabolic…”
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Valproate and Acetyl-l-carnitine Prevent Methamphetamine-Induced Behavioral Sensitization in Mice by COCCURELLO, ROBERTO, CAPRIOLI, ANTONIO, GHIRARDI, ORLANDO, VIRMANI, ASHRAF

“…This study deals with the possible inhibitory role played by acetyl‐l‐carnitine (ALC) against methamphetamine (METH)‐induced behavioral sensitization. Because…”
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The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models by Caprioli, Antonio, Coccurello, Roberto, Rapino, Cinzia, Di Serio, Stefano, Di Tommaso, Monia, Vertechy, Mario, Vacca, Valentina, Battista, Natalia, Pavone, Flaminia, Maccarrone, Mauro, Borsini, Franco

“…The effect of the enol carbamate 1-biphenyl-4-ylethenyl piperidine-1-carboxylate (ST4070), a novel reversible inhibitor of fatty acid amide hydrolase (FAAH),…”
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Sporadic Autonomic Dysregulation and Death Associated with Excessive Serotonin Autoinhibition by Audero, Enrica, Coppi, Elisabetta, Mlinar, Boris, Rossetti, Tiziana, Caprioli, Antonio, Banchaabouchi, Mumna Al, Corradetti, Renato, Gross, Cornelius

“…Sudden infant death syndrome is the leading cause of death in the postneonatal period in developed countries. Postmortem studies show alterations in serotonin…”
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Non-native glyceraldehyde-3-phosphate dehydrogenase can be an intrinsic component of amyloid structures by Naletova, Irina, Schmalhausen, Elena, Kharitonov, Aleksey, Katrukha, Aleksey, Saso, Luciano, Caprioli, Antonio, Muronetz, Vladimir

“…Interactions between different forms of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and amyloid-beta peptide (1–42) were investigated by direct (surface…”
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Social encounter with a novel partner in adolescent rats: Activation of the central endocannabinoid system by Marco, Eva María, Rapino, Cinzia, Caprioli, Antonio, Borsini, Franco, Maccarrone, Mauro, Laviola, Giovanni

“…► The endocannabinoid system is critically involved in social emotion. ► Striatal anandamide levels increased upon encounter with a novel partner. ►…”
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Discovery of Potent Inhibitors of Human and Mouse Fatty Acid Amide Hydrolases by Butini, Stefania, Brindisi, Margherita, Gemma, Sandra, Minetti, Patrizia, Cabri, Walter, Gallo, Grazia, Vincenti, Silvia, Talamonti, Emanuela, Borsini, Franco, Caprioli, Antonio, Stasi, Maria Antonietta, Di Serio, Stefano, Ros, Sindu, Borrelli, Giuseppe, Maramai, Samuele, Fezza, Filomena, Campiani, Giuseppe, Maccarrone, Mauro

“…Fatty acid amide hydrolase (FAAH, EC 3.5.1.99) is the main enzyme catabolizing endocannabinoid fatty acid amides. FAAH inactivation promotes beneficial effects…”
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Animal models of Parkinson׳s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535) by Stasi, Maria Antonietta, Minetti, Patrizia, Lombardo, Katia, Riccioni, Teresa, Caprioli, Antonio, Vertechy, Mario, Di Serio, Stefano, Pace, Silvia, Borsini, Franco

“…Antagonism of the adenosine A2A receptor represents a promising strategy for non-dopaminergic treatment of Parkinson׳s disease (PD). Previously, the adenosine…”
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Litter Gender Composition Affects Maternal Behavior of the Primiparous Mouse Dam (Mus musculus ) by Alleva, Enrico, Caprioli, Antonio, Laviola, Giovanni

“…Thirty-nine litters of the outbred Swiss CD-1 mouse strain were reduced at birth to 6 pups, according to three conditions: MM (all males), MF (3 males and 3…”
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30 Days of Continuous Olanzapine Infusion Determines Energy Imbalance, Glucose Intolerance, Insulin Resistance, and Dyslipidemia in Mice by COCCURELLO, Roberto, BRINA, Daniela, CAPRIOLI, Antonio, CONTI, Roberto, GHIRARDI, Orlando, SCHEPIS, Filippo, MOLES, Anna

“…The aim of this study was to model in mice the association between metabolic syndrome and the administration of atypical antipsychotic (AAP). Two dosages (4…”
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The effect of early maternal separation on brain derived neurotrophic factor and monoamine levels in adult heterozygous reeler mice by Ognibene, Elisa, Adriani, Walter, Caprioli, Antonio, Ghirardi, Orlando, Ali, Syed F., Aloe, Luigi, Laviola, Giovanni

“…The reeler heterozygous (HZ) mice have provided a model for studying the relationship between reelin (a protein of extracellular matrix) haploinsufficiency and…”
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Spatial learning and memory in the radial maze: a longitudinal study in rats from 4 to 25 months of age by Caprioli, A, Ghirardi, O, Giuliani, A, Ramacci, M T, Angelucci, L

“…This longitudinal study was designed to investigate whether previous experience may influence performances and strategies of rats tested in the radial maze…”
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A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase by Gattinoni, Sonia, Simone, Chiara De, Dallavalle, Sabrina, Fezza, Filomena, Nannei, Raffaella, Battista, Natalia, Minetti, Patrizia, Quattrociocchi, Gianandrea, Caprioli, Antonio, Borsini, Franco, Cabri, Walter, Penco, Sergio, Merlini, Lucio, Maccarrone, Mauro

“…A series of oxime carbamates have been identified as potent inhibitors of fatty acid amide hydrolase (FAAH), an important regulatory enzyme of the…”
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Enol Carbamates as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) Endowed with High Selectivity for FAAH over the Other Targets of the Endocannabinoid System by Gattinoni, Sonia, De Simone, Chiara, Dallavalle, Sabrina, Fezza, Filomena, Nannei, Raffaella, Amadio, Daniele, Minetti, Patrizia, Quattrociocchi, Gianandrea, Caprioli, Antonio, Borsini, Franco, Cabri, Walter, Penco, Sergio, Merlini, Lucio, Maccarrone, Mauro

“…FAAH inhibitors: This study identifies a new class of enol carbamates as potent, reversible inhibitors of fatty acid amide hydrolase (FAAH), endowed with high…”
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Effects of the increase in neuronal fatty acids availability on food intake and satiety in mice by Coccurello, Roberto, Caprioli, Antonio, Bellantuono, Sara, D’Amato, Francesca R., Conti, Roberto, Giannessi, Fabio, Borsini, Franco, Moles, Anna

“…Rationale Neurons detect free fatty acids (FFAs) availability and use this nutritional status to modulate feeding and control body weight. Objectives The work…”
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An inhibitor of neuronal exocytosis (DD04107) displays long-lasting in vivo activity against chronic inflammatory and neuropathic pain by Ponsati, Berta, Carreño, Cristina, Curto-Reyes, Verdad, Valenzuela, Belen, Duart, María José, Van den Nest, Wim, Cauli, Omar, Beltran, Beatriz, Fernandez, Jimena, Borsini, Franco, Caprioli, Antonio, Di Serio, Stefano, Veretchy, Mario, Baamonde, Ana, Menendez, Luis, Barros, Francisco, de la Pena, Pilar, Borges, Ricardo, Felipo, Vicente, Planells-Cases, Rosa, Ferrer-Montiel, Antonio

“…Small peptides patterned after the N terminus of the synaptosomal protein of 25 kDa, a member of the protein complex implicated in Ca(2+)-dependent neuronal…”
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Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease by Shalova, Irina N., Cechalova, Katerina, Rehakova, Zuzana, Dimitrova, Petya, Ognibene, Elisa, Caprioli, Antonio, Schmalhausen, Elena V., Muronetz, Vladimir I., Saso, Luciano

“…Recently, a relationship between glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and the β-amyloid precursor protein (βAPP) in relationship with the…”
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