Search Results - "Caprio, Massimiliano"
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Molecular mechanisms underlying metabolic syndrome: the expanding role of the adipocyte
Published in The FASEB journal (01-10-2017)“…ABSTRACT The metabolic syndrome (MetS) is defined as a cluster of 3 or more metabolic and cardiovascular risk factors and represents a serious problem for…”
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Effects of a ketogenic diet in overweight women with polycystic ovary syndrome
Published in Journal of translational medicine (27-02-2020)“…Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women during reproductive age. It is characterised clinically by oligo-ovulation or…”
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3
Vitamin D: not just the bone. Evidence for beneficial pleiotropic extraskeletal effects
Published in Eating and weight disorders (01-03-2017)“…Vitamin D is a fat-soluble vitamin and a steroid hormone that plays a central role in maintaining calcium-phosphorus and bone homeostasis in close interaction…”
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4
The dark side of the spoon - glucose, ketones and COVID-19: a possible role for ketogenic diet?
Published in Journal of translational medicine (20-11-2020)“…The novel coronavirus disease (COVID-19) is posing a serious challenge to the health-care systems worldwide, with an enormous impact on health conditions and…”
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Mineralocorticoid Receptors in Metabolic Syndrome: From Physiology to Disease
Published in Trends in endocrinology and metabolism (01-03-2020)“…Over the past decade, several studies have shown that activity of extra-renal mineralocorticoid receptors (MR) regulates vascular tone, adipogenesis, adipose…”
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RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives
Published in Journal of experimental & clinical cancer research (08-01-2019)“…RANKL/RANK/OPG system consists of three essential signaling molecules: i) the receptor activator of nuclear factor (NF)-kB-ligand (RANKL), ii) the receptor…”
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Very-Low-Calorie Ketogenic Diet as a Safe and Valuable Tool for Long-Term Glycemic Management in Patients with Obesity and Type 2 Diabetes
Published in Nutrients (26-02-2021)“…Obesity-related type 2 diabetes represents one of the most difficult challenges for the healthcare system. This retrospective study aims to determine the…”
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Hydroxychloroquine in the COVID-19 pandemic era: in pursuit of a rational use for prophylaxis of SARS-CoV-2 infection
Published in Expert review of anti-infective therapy (02-01-2021)“…Over the last few months, coronavirus disease 2019 (COVID-19) pandemic caused by the novel coronavirus SARS-CoV-2 has posed a serious threat to public health…”
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Exploring the Role of Skeletal Muscle in Insulin Resistance: Lessons from Cultured Cells to Animal Models
Published in International journal of molecular sciences (01-09-2021)“…Skeletal muscle is essential to maintain vital functions such as movement, breathing, and thermogenesis, and it is now recognized as an endocrine organ…”
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Health Effects of Red Wine Consumption: A Narrative Review of an Issue That Still Deserves Debate
Published in Nutrients (01-04-2023)“…A strong controversy persists regarding the effect of red wine (RW) consumption and health. Guidelines for the prevention of cardiovascular diseases (CVD) and…”
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The Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia Syndrome and Chronic Musculoskeletal Pain
Published in Nutrients (22-07-2022)“…Fibromyalgia syndrome (FMS) and chronic widespread musculoskeletal pain (CMP) are diffuse suffering syndromes that interfere with normal activities…”
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Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders
Published in Nutrients (26-01-2021)“…: Ketogenic diet (KD) is a nutritional approach that restricts daily carbohydrates, replacing most of the reduced energy with fat, while maintaining an…”
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Influence of Vitamin D on Islet Autoimmunity and Beta-Cell Function in Type 1 Diabetes
Published in Nutrients (11-09-2019)“…Type 1 diabetes (T1D) is a chronic autoimmune disease leading to immune-mediated destruction of pancreatic beta cells, resulting in the need for insulin…”
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14
The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy
Published in Nature communications (25-09-2012)“…Pathological growth of cardiomyocytes (hypertrophy) is a major determinant for the development of heart failure, one of the leading medical causes of mortality…”
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Endothelial Mineralocorticoid Receptors Contribute to Vascular Inflammation in Atherosclerosis in a Sex-Specific Manner
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2019)“…MR (mineralocorticoid receptor) activation is associated with cardiovascular ischemia in humans. This study explores the role of the MR in atherosclerotic mice…”
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Essential role of ICAM-1 in aldosterone-induced atherosclerosis
Published in International journal of cardiology (01-04-2017)“…Abstract Objective Elevated aldosterone is associated with increased risk of atherosclerosis complications, whereas treatment with mineralocorticoid receptor…”
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Neutral Effect of Skeletal Muscle Mineralocorticoid Receptor on Glucose Metabolism in Mice
Published in International journal of molecular sciences (01-04-2023)“…The mineralocorticoid receptor (MR) is able to regulate the transcription of a number of genes in the myotube, although its roles in skeletal muscle (SM)…”
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Role of Aldosterone and Mineralocorticoid Receptor in Cardiovascular Aging
Published in Frontiers in endocrinology (Lausanne) (23-08-2019)“…The mineralocorticoid receptor (MR) was originally identified as a regulator of blood pressure, able to modulate renal sodium handling in response to its…”
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Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high‐fat‐diet‐fed mice
Published in The FASEB journal (01-08-2014)“…The mineralocorticoid receptor (MR) controls adipocyte function, but its role in the conversion of white adipose tissue (WAT) into thermogenic fat has not been…”
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Neuroendocrine and Metabolic Effects of Low-Calorie and Non-Calorie Sweeteners
Published in Frontiers in endocrinology (Lausanne) (16-07-2020)“…Since excessive sugar consumption has been related to the development of chronic metabolic diseases prevalent in the western world, the use of sweeteners has…”
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