Search Results - "Cappuccilli, Guido"

AXL-Receptor Targeted 14FN3 Based Single Domain Proteins (Pronectins™) from 3 Synthetic Human Libraries as Components for Exploring Novel Bispecific Constructs against Solid Tumors by Hokanson, Craig A, Zacco, Emanuela, Cappuccilli, Guido, Odineca, Tatjana, Crea, Roberto

“…A highly specific AXL-receptor targeted family of non-immunoglobulin, single domain protein binders (Pronectins™) have been isolated from three (3) synthetic…”
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A General Method for Greatly Improving the Affinity of Antibodies by Using Combinatorial Libraries by Rajpal, Arvind, Beyaz, Nurten, Haber, Lauric, Cappuccilli, Guido, Yee, Helena, Bhatt, Ramesh R., Takeuchi, Toshihiko, Lerner, Richard A., Crea, Roberto

“…Look-through mutagenesis (LTM) is a multidimensional mutagenesis method that simultaneously assesses and optimizes combinatorial mutations of selected amino…”
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Data-Driven Antibody Engineering Using Genedata Biologics by Wendt, Maria, Cappuccilli, Guido

“…Genedata Biologics is a novel informatics platform specifically designed for biologics R&D. Here, we discuss the main principles employed in designing such a…”
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Synthetic Antibodies Designed on Natural Sequence Landscapes by Zhai, Wenwu, Glanville, Jacob, Fuhrmann, Markus, Mei, Li, Ni, Irene, Sundar, Purnima D., Van Blarcom, Thomas, Abdiche, Yasmina, Lindquist, Kevin, Strohner, Ralf, Telman, Dilduz, Cappuccilli, Guido, Finlay, William J.J., Van den Brulle, Jan, Cox, David R., Pons, Jaume, Rajpal, Arvind

“…We present a method for synthetic antibody library generation that combines the use of high-throughput immune repertoire analysis and a novel synthetic…”
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Engineering highly thermostable xylanase variants using an enhanced combinatorial library method by Hokanson, Craig A., Cappuccilli, Guido, Odineca, Tatjana, Bozic, Marino, Behnke, Craig A., Mendez, Michael, Coleman, William J., Crea, Roberto

“…A new directed evolution method was used to enhance the thermostability of the wild-type GH11 xylanase 2 (known as BD-11) from Hypocrea jecorina (Trichoderma…”
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