Search Results - "Cappariello, A."

An experimental therapy to improve skeletal growth and prevent bone loss in a mouse model overexpressing IL-6 by Del Fattore, A., Cappariello, A., Capulli, M., Rucci, N., Muraca, M., De Benedetti, F., Teti, A.

“…Summary Premature osteoporosis and stunted growth are common complications of childhood chronic inflammatory disease. Presently, no treatment regimens are…”
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Clinical, genetic, and cellular analysis of 49 osteopetrotic patients: implications for diagnosis and treatment by Del Fattore, A, Peruzzi, B, Rucci, N, Recchia, I, Cappariello, A, Longo, M, Fortunati, D, Ballanti, P, Iacobini, M, Luciani, M, Devito, R, Pinto, R, Caniglia, M, Lanino, E, Messina, C, Cesaro, S, Letizia, C, Bianchini, G, Fryssira, H, Grabowski, P, Shaw, N, Bishop, N, Hughes, D, Kapur, R P, Datta, H K, Taranta, A, Fornari, R, Migliaccio, S, Teti, A

“…Background: Osteopetrosis, a genetic disease characterised by osteoclast failure, is classified into three forms: infantile malignant autosomal recessive…”
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Regulatory loops involving IGFBP5 account for a fine tuning regulation of osteoblast and osteoclast activity in the context of the IL-6 pathway by Peruzzi, B, Cappariello, A, Del Fattore, A, Rucci, N, De Benedetti, F, Teti, A

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Engineered tridimensional (3D) hydroxyapatite (HA) scaffold to support bone resorption by Cappariello, A, Peruzzi, B, Del Fattore, A, Ugazio, A, Teti, A.M

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In vivo relevance of the interplay between IL-6 and C-SRC in the regulation of osteoblast function. Involvement of the IGF-1/IGFBPS axis by Peruzzi, B, Cappariello, A, Rucci, N, De Benedetti, F, Teti, A

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New experimental therapy to rescue impaired skeletal growth and bone loss in a mouse model of IL-6 dependent juvenile inflammatory diseases by Del Fattore, A, Capannolo, M, Peruzzi, B, Cappariello, A, Carvello, F, Rucci, N, De Benedetti, F, Teti, A

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Inhibition of c-Src reduces IL-6 expression in vivo and in vitro by Peruzzi, B, Cappariello, A, Rucci, N, De Benedetti, F, Teti, A

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Inoculation of osteoclast precursors improves the phenotype of osteopetrotic oc/oc mice by Cappariello, A, Del Fattore, A, Berardi, A.C, Peruzzi, B, Rucci, N, Longo, M, Ugazio, A, Bottazzo, G.F, Teti, A

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Genetics, pathogenesis and complications of osteopetrosis by Del Fattore, Andrea, Cappariello, Alfredo, Teti, Anna

“…Abstract Human osteopetrosis is a rare genetic disorder caused by osteoclast failure, which ranges widely in severity. In the most severe forms, deficient bone…”
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A New Heterozygous Mutation (R714C) of the Osteopetrosis Gene, Pleckstrin Homolog Domain Containing Family M (With Run Domain) Member 1 (PLEKHM1), Impairs Vesicular Acidification and Increases TRACP Secretion in Osteoclasts by Del Fattore, Andrea, Fornari, Rachele, Van Wesenbeeck, Liesbeth, de Freitas, Fenna, Timmermans, Jean‐Pierre, Peruzzi, Barbara, Cappariello, Alfredo, Rucci, Nadia, Spera, Giovanni, Helfrich, Miep H, Van Hul, Wim, Migliaccio, Silvia, Teti, Anna

“…We studied phenotypic and cellular aspects in a patient with a heterozygous mutation of the PLEKHM1 gene and obtained some indications regarding the role of…”
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