Search Results - "Caporali, Paola"

Linear Cyclodextrin Polymer Prodrugs as Novel Therapeutics for Niemann-Pick Type C1 Disorder by Kulkarni, Aditya, Caporali, Paola, Dolas, Atul, Johny, Soniya, Goyal, Sandeep, Dragotto, Jessica, Macone, Alberto, Jayaraman, Ramesh, Fiorenza, Maria Teresa

“…Niemann-Pick Type C1 disorder (NPC) is a rare lysosomal storage disease characterized by the accumulation of cholesterol in lysosomes. NPC has no FDA approved…”
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A single intraperitoneal injection of endotoxin in rats induces long-lasting modifications in behavior and brain protein levels of TNF-α and IL-18 by Bossù, Paola, Cutuli, Debora, Palladino, Ilaria, Caporali, Paola, Angelucci, Francesco, Laricchiuta, Daniela, Gelfo, Francesca, De Bartolo, Paola, Caltagirone, Carlo, Petrosini, Laura

“…Systemic inflammation might cause neuronal damage and sustain neurodegenerative diseases and behavior impairment, with the participation of pro-inflammatory…”
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The endocannabinoid system is affected by cholesterol dyshomeostasis: Insights from a murine model of Niemann Pick type C disease by Oddi, Sergio, Caporali, Paola, Dragotto, Jessica, Totaro, Antonio, Maiolati, Marzia, Scipioni, Lucia, Angelucci, Clotilde Beatrice, Orsini, Cristina, Canterini, Sonia, Rapino, Cinzia, Maccarrone, Mauro, Fiorenza, Maria Teresa

“…The dyshomeostasis of intracellular cholesterol trafficking is typical of the Niemann-Pick type C (NPC) disease, a fatal inherited lysosomal storage disorder…”
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Pre-reproductive Parental Enriching Experiences Influence Progeny's Developmental Trajectories by Cutuli, Debora, Berretta, Erica, Laricchiuta, Daniela, Caporali, Paola, Gelfo, Francesca, Petrosini, Laura

“…While the positive effects of environmental enrichment (EE) applied after weaning, in adulthood, during aging, or even in the presence of brain damage have…”
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Effects of Omega-3 Fatty Acid Supplementation on Cognitive Functions and Neural Substrates: A Voxel-Based Morphometry Study in Aged Mice by Cutuli, Debora, Pagani, Marco, Caporali, Paola, Galbusera, Alberto, Laricchiuta, Daniela, Foti, Francesca, Neri, Cristina, Spalletta, Gianfranco, Caltagirone, Carlo, Petrosini, Laura, Gozzi, Alessandro

“…Human and experimental studies have revealed putative neuroprotective and pro-cognitive effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) in aging,…”
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Influence of Pre-reproductive Maternal Enrichment on Coping Response to Stress and Expression of c-Fos and Glucocorticoid Receptors in Adolescent Offspring by Cutuli, Debora, Berretta, Erica, Pasqualini, Greta, De Bartolo, Paola, Caporali, Paola, Laricchiuta, Daniela, Sampedro-Piquero, Patricia, Gelfo, Francesca, Pesoli, Matteo, Foti, Francesca, Begega, Azucena, Petrosini, Laura

“…Environmental enrichment (EE) is an experimental setting broadly used for investigating the effects of complex social, cognitive, and sensorimotor stimulations…”
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Neuroprotective effects of donepezil against cholinergic depletion by Cutuli, Debora, De Bartolo, Paola, Caporali, Paola, Tartaglione, Anna Maria, Oddi, Diego, D'Amato, Francesca Romana, Nobili, Annalisa, D'Amelio, Marcello, Petrosini, Laura

“…Intraparenchymal injections of the immunotoxin 192-IgG-saporin into medial septum and nucleus basalis magnocellularis causes a selective depletion of basal…”
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Effects of Anti-NMDA Antibodies on Functional Recovery and Synaptic Rearrangement Following Hemicerebellectomy by Laricchiuta, Daniela, Cavallucci, Virve, Cutuli, Debora, De Bartolo, Paola, Caporali, Paola, Foti, Francesca, Finke, Carsten, D’Amelio, Marcello, Manto, Mario, Petrosini, Laura

“…The compensation that follows cerebellar lesions is based on synaptic modifications in many cortical and subcortical regions, although its cellular mechanisms…”
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Effects of pre-reproductive maternal enrichment on maternal care, offspring's play behavior and oxytocinergic neurons by Cutuli, Debora, Berretta, Erica, Caporali, Paola, Sampedro-Piquero, Patricia, De Bartolo, Paola, Laricchiuta, Daniela, Gelfo, Francesca, Pesoli, Matteo, Foti, Francesca, Farioli Vecchioli, Stefano, Petrosini, Laura

“…Potentiating social, cognitive, and sensorimotor stimulations the Environmental Enrichment (EE) increases levels of novelty and complexity experienced by…”
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Pre-reproductive maternal enrichment influences offspring developmental trajectories: motor behavior and neurotrophin expression by Caporali, Paola, Cutuli, Debora, Gelfo, Francesca, Laricchiuta, Daniela, Foti, Francesca, De Bartolo, Paola, Mancini, Laura, Angelucci, Francesco, Petrosini, Laura

“…Environmental enrichment is usually applied immediately after weaning or in adulthood, with strong effects on CNS anatomy and behavior. To examine the…”
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Decreased neural stem cell proliferation and olfaction in mouse models of Niemann-Pick C1 disease and the response to hydroxypropyl-[beta]-cyclodextrin by Dragotto, Jessica, Palladino, Giampiero, Canterini, Sonia, Caporali, Paola, Patil, Rutaraj, Fiorenza, Maria Teresa, Erickson, Robert P

“…The Npc1.sup.nih/nih-null model and the Npc1.sup.nmf164/nmf164 hypomorph models of Niemann-Pick C1 (NPC1) disease show defects in olfaction. We have tested the…”
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n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice by Cutuli, Debora, De Bartolo, Paola, Caporali, Paola, Laricchiuta, Daniela, Foti, Francesca, Ronci, Maurizio, Rossi, Claudia, Neri, Cristina, Spalletta, Gianfranco, Caltagirone, Carlo, Farioli-Vecchioli, Stefano, Petrosini, Laura

“…As major components of neuronal membranes, omega-3 polyunsaturated acids (n-3 PUFA) exhibit a wide range of regulatory functions, modulating from synaptic…”
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Decreased neural stem cell proliferation and olfaction in mouse models of Niemann–Pick C1 disease and the response to hydroxypropyl-β-cyclodextrin by Dragotto, Jessica, Palladino, Giampiero, Canterini, Sonia, Caporali, Paola, Patil, Rutaraj, Fiorenza, Maria Teresa, Erickson, Robert P.

“…The Npc1 nih/nih - null model and the Npc1 nmf164/nmf164 hypomorph models of Niemann–Pick C1 (NPC1) disease show defects in olfaction. We have tested the…”
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Developmental delay in motor skill acquisition in Niemann-Pick C1 mice reveals abnormal cerebellar morphogenesis by Caporali, Paola, Bruno, Francesco, Palladino, Giampiero, Dragotto, Jessica, Petrosini, Laura, Mangia, Franco, Erickson, Robert P, Canterini, Sonia, Fiorenza, Maria Teresa

“…Niemann-Pick type C1 (NPC1) disease is a lysosomal storage disorder caused by defective intracellular trafficking of exogenous cholesterol. Purkinje cell (PC)…”
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Monoclonal antibodies to 65kDa glutamate decarboxylase induce epitope specific effects on motor and cognitive functions in rats by Hampe, Christiane S, Petrosini, Laura, De Bartolo, Paola, Caporali, Paola, Cutuli, Debora, Laricchiuta, Daniela, Foti, Francesca, Radtke, Jared R, Vidova, Veronika, Honnorat, Jérôme, Manto, Mario

“…Stiff Person Syndrome (SPS) is a rare autoimmune movement disorder characterized by the presence of autoantibodies specific to the smaller isoform of glutamate…”
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Pre-reproductive maternal enrichment influences rat maternal care and offspring developmental trajectories: behavioral performances and neuroplasticity correlates by Cutuli, Debora, Caporali, Paola, Gelfo, Francesca, Angelucci, Francesco, Laricchiuta, Daniela, Foti, Francesca, De Bartolo, Paola, Bisicchia, Elisa, Molinari, Marco, Farioli Vecchioli, Stefano, Petrosini, Laura

“…Environmental enrichment (EE) is a widely used paradigm for investigating the influence of complex stimulations on brain and behavior. Here we examined whether…”
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Interaction does Count: A Cross-Fostering Study on Transgenerational Effects of Pre-reproductive Maternal Enrichment by Caporali, Paola, Cutuli, Debora, Gelfo, Francesca, Laricchiuta, Daniela, Foti, Francesca, De Bartolo, Paola, Angelucci, Francesco, Petrosini, Laura

“…Pre-reproductive environmental enrichment of female rats influences sensorimotor development and spatial behavior of the offspring, possibly through the…”
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A single intraperitoneal injection of endotoxin in rats induces long-lasting modifications in behavior and brain protein levels of TNF-[alpha] and IL-18 by Bossù, Paola, Cutuli, Debora, Palladino, Ilaria, Caporali, Paola, Angelucci, Francesco, Laricchiuta, Daniela, Gelfo, Francesca, De Bartolo, Paola, Caltagirone, Carlo, Petrosini, Laura

“…Background Systemic inflammation might cause neuronal damage and sustain neurodegenerative diseases and behavior impairment, with the participation of…”
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