Search Results - "Caplan, Y H"

Urine Drug Testing of Chronic Pain Patients: Licit and Illicit Drug Patterns by Cone, Edward J., Caplan, Yale H., Black, David L., Robert, Timothy, Moser, Frank

“…Chronic pain patients are frequently maintained on one or more powerful opioid medications in combination with other psychoactive medications. Urine tests…”
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Oxycodone Involvement in Drug Abuse Deaths. II. Evidence for Toxic Multiple Drug-Drug Interactions by Cone, Edward J., Fant, Reginald V., Rohay, Jeffrey M., Caplan, Yale H., Ballina, Mayra, Reder, Robert F., Haddox, J. David

“…Recent surveys suggest that the abuse of drugs, often in combination, is pervasive throughout society. Adverse consequences of drug abuse tend to be attributed…”
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Alternative Specimens for Workplace Drug Testing by Caplan, Yale H., Goldberger, Bruce A.

“…Recent advances in analytical techniques have enabled the detection of drugs and drug metabolites in alternative biological specimens for the purposes of…”
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Oxycodone Involvement in Drug Abuse Deaths: A DAWN-Based Classification Scheme Applied to an Oxycodone Postmortem Database Containing Over 1000 Cases by Cone, Edward J., Fant, Reginald V., Rohay, Jeffrey M., Caplan, Yale H., Ballina, Mayra, Reder, Robert F., Spyker, Daniel, Haddox, J. David

“…An oxycodone postmortem database was created from 1243 solicited cases from Medical Examiner and Coroner (ME/C) offices in 23 states in the United States over…”
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The Characterization of Human Urine for Specimen Validity Determination in Workplace Drug Testing: A Review by Cook, Janine Denis, Caplan, Yale H., LoDico, Charles P., Bush, Donna M.

“…One challenge facing the laboratory forensic toxicologist today is verifying the validity of the random urine specimen submitted for workplace drugs of abuse…”
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Urine pH: the Effects of Time and Temperature after Collection by Cook, Janine D., Strauss, Kathy A., Caplan, Yale H., LoDico, Charles P., Bush, Donna M.

“…The Mandatory Guidelines for Federal Workplace Drug Testing Programs provide criteria for specimen validity testing, including urine pH cut-offs, to report a…”
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Disposition of heroin and its metabolites in heroin-related deaths by Goldberger, B A, Cone, E J, Grant, T M, Caplan, Y H, Levine, B S, Smialek, J E

“…Although many deaths occur annually from heroin intoxication, the presence of heroin has not been reported in postmortem tissues. Recognizing heroin's…”
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Detection of Methadone, Methadone Metabolites, and Other Illicit Drugs of Abuse in Hair of Methadone-Treatment Subjects by Goldberger, Bruce A., Darraj, Abeer G., Caplan, Yale H., Cone, Edward J.

“…The disposition of methadone, its metabolites, and other illicit drugs of abuse was investigated in head hair samples collected from heroin users (N = 20)…”
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Testing human hair for drugs of abuse. III. Identification of heroin and 6-acetylmorphine as indicators of heroin use by Goldberger, B A, Caplan, Y H, Maguire, T, Cone, E J

“…Hair samples from 20 documented heroin users contained 6-acetylmorphine, a unique metabolite of heroin, in all samples. Heroin was identified in smaller…”
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The Defined HHS/DOT Substituted Urine Criteria Validated Through a Controlled Hydration Study by Edgell, Kenneth, Caplan, Yale H., Glass, Leon R., Cook, Janine Denis

“…This controlled hydration study was designed to validate the substitution criteria used by the Substance Abuse and Mental Health Services Administration…”
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Oral Fluid Drug Testing of Chronic Pain Patients. II. Comparison of Paired Oral Fluid and Urine Specimens by Heltsley, Rebecca, DePriest, Anne, Black, David L., Crouch, Dennis J., Robert, Tim, Marshall, Lucas, Meadors, Viola M., Caplan, Yale H., Cone, Edward J.

“…A clinical study was conducted to compare the use of oral fluid to urine for compliance monitoring of pain patients. Patients (n = 133) undergoing treatment…”
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Measurement of heroin and its metabolites by isotope-dilution electron-impact mass spectrometry by Goldberger, B A, Darwin, W D, Grant, T M, Allen, A C, Caplan, Y H, Cone, E J

“…A solid-phase extraction procedure was developed for the isolation of heroin, 6-acetylmorphine, and morphine from blood, plasma, saliva, and urine with…”
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Effect of glutaraldehyde (UrinAid) on detection of abused drugs in urine by immunoassay by Goldberger, B A, Caplan, Y H

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A comprehensive study of the stability of cocaine and its metabolites by Isenschmid, D S, Levine, B S, Caplan, Y H

“…The stability of cocaine (COC) in blood bank blood, postmortem human whole blood, and buffers was evaluated with consideration for the presence of the…”
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Evidence of Morphine Metabolism to Hydromorphone in Pain Patients Chronically Treated with Morphine by Cone, Edward J., Heit, Howard A., Caplan, Yale H., Gourlay, Douglas

“…Minor metabolic pathways in human subjects have been shown to exist for the conversion of codeine to hydrocodone but have not been reported for the metabolic…”
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Concentration of cocaine and metabolites in plasma of humans following intravenous administration and smoking of cocaine by Isenschmid, D S, Fischman, M W, Foltin, R W, Caplan, Y H

“…Plasma was obtained from 10 human subjects at various intervals after administration of two rapid doses of cocaine, either intravenously or by smoking, and…”
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Vitreous humor in the evaluation of postmortem blood ethanol concentrations by Caplan, Y H, Levine, B

“…Many studies have been published comparing blood (B) ethanol (EtOH) and vitreous humor (VH) EtOH concentrations. We conducted a similar study of routinely…”
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Interpretation of low postmortem concentrations of ethanol by Levine, B, Smith, M L, Smialek, J E, Caplan, Y H

“…The interpretation of postmortem blood ethanol concentrations (BAC), especially those less than 0.05 g/dL can be complicated by postmortem ethanol formation…”
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Fluorescence polarization immunoassay evaluated for screening for amphetamine and methamphetamine in urine by Caplan, Y H, Levine, B, Goldberger, B

“…We studied the recently developed Abbott fluorescence polarization immunoassay (FPIA) for amphetamine and methamphetamine in urine and compared the results…”
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Chloral hydrate overdose: trichloroethanol detection by gas chromatography/mass spectrometry by Heller, P F, Goldberger, B A, Caplan, Y H

“…A case is presented where an individual ingested a fatal dose of chloral hydrate. Trichloroethanol (TCE), the metabolite of chloral hydrate, was initially…”
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