Search Results - "Capkova, Lenka"

Breast Cancer Classification Based on Proteotypes Obtained by SWATH Mass Spectrometry by Bouchal, Pavel, Schubert, Olga T., Faktor, Jakub, Capkova, Lenka, Imrichova, Hana, Zoufalova, Karolina, Paralova, Vendula, Hrstka, Roman, Liu, Yansheng, Ebhardt, Holger Alexander, Budinska, Eva, Nenutil, Rudolf, Aebersold, Ruedi

“…Accurate classification of breast tumors is vital for patient management decisions and enables more precise cancer treatment. Here, we present a quantitative…”
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Limited efficacy of daratumumab in multiple myeloma with extramedullary disease by Jelinek, Tomas, Sevcikova, Tereza, Zihala, David, Popkova, Tereza, Kapustova, Veronika, Broskevicova, Lucie, Capkova, Lenka, Rihova, Lucie, Bezdekova, Renata, Sevcikova, Sabina, Zidlik, Vladimir, Havel, Martin, Plonkova, Hana, Jungova, Alexandra, Minarik, Jiri, Stork, Martin, Pour, Ludek, Pavlicek, Petr, Spicka, Ivan, Maisnar, Vladimir, Radocha, Jakub, Simicek, Michal, Hajek, Roman

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Survival benefit of ixazomib, lenalidomide and dexamethasone (IRD) over lenalidomide and dexamethasone (Rd) in relapsed and refractory multiple myeloma patients in routine clinical practice by Minarik, Jiri, Pika, Tomas, Radocha, Jakub, Jungova, Alexandra, Straub, Jan, Jelinek, Tomas, Pour, Ludek, Pavlicek, Petr, Mistrik, Martin, Brozova, Lucie, Krhovska, Petra, Machalkova, Katerina, Jindra, Pavel, Spicka, Ivan, Plonkova, Hana, Stork, Martin, Bacovsky, Jaroslav, Capkova, Lenka, Sykora, Michal, Kessler, Petr, Stejskal, Lukas, Heindorfer, Adriana, Ullrychova, Jana, Skacel, Tomas, Maisnar, Vladimir, Hajek, Roman

“…We have performed a head to head comparison of all-oral triplet combination of ixazomib, lenalidomide and dexamethasone (IRD) versus lenalidomide and…”
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Targeted proteomics driven verification of biomarker candidates associated with breast cancer aggressiveness by Procházková, Iva, Lenčo, Juraj, Fučíková, Alena, Dresler, Jiří, Čápková, Lenka, Hrstka, Roman, Nenutil, Rudolf, Bouchal, Pavel

“…Breast cancer is the most common and molecularly relatively well characterized malignant disease in women, however, its progression to metastatic cancer…”
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Ixazomib-lenalidomide-dexamethasone in routine clinical practice: effectiveness in relapsed/refractory multiple myeloma by Hájek, Roman, Minařík, Jiří, Straub, Jan, Pour, Luděk, Jungova, Alexandra, Berdeja, Jesus G, Boccadoro, Mario, Brozova, Lucie, Spencer, Andrew, Rhee, Frits van, Vela-Ojeda, Jorge, Thompson, Michael A, Abonour, Rafat, Chari, Ajai, Cook, Gordon, Costello, Caitlin L, Davies, Faith E, Hungria, Vania Tm, Lee, Hans C, Leleu, Xavier, Puig, Noemi, Rifkin, Robert M, Terpos, Evangelos, Usmani, Saad Z, Weisel, Katja C, Zonder, Jeffrey A, Bařinová, Magda, Kuhn, Matyáš, Šilar, Jiří, Čápková, Lenka, Galvez, Kenny, Lu, Jin, Elliott, Jennifer, Stull, Dawn Marie, Ren, Kaili, Maisnar, Vladimír

“…To evaluate the effectiveness and safety of ixazomib-lenalidomide-dexamethasone (IRd) in relapsed/refractory multiple myeloma in routine clinical practice…”
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Joint analysis of histopathology image features and gene expression in breast cancer by Popovici, Vlad, Budinská, Eva, Čápková, Lenka, Schwarz, Daniel, Dušek, Ladislav, Feit, Josef, Jaggi, Rolf

“…Genomics and proteomics are nowadays the dominant techniques for novel biomarker discovery. However, histopathology images contain a wealth of information…”
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Pull-down Assay on Streptavidin Beads and Surface Plasmon Resonance Chips for SWATH-MS-based Interactomics by MARYÁŠ, JOSEF, FAKTOR, JAKUB, ČÁPKOVÁ, LENKA, MÜLLER, PETR, SKLÁDAL, PETR, BOUCHAL, PAVEL

“…Background/Aim: Pul-down assay is a popular in vitro method for identification of physical interactors of selected proteins. Here, for the first time, we…”
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Real-world evidence of efficacy and safety of pomalidomide and dexamethasone in relapsed/refractory multiple myeloma patients: Czech registry data by Sandecka, Viera, Pour, Luděk, Špička, Ivan, Minařík, Jiří, Radocha, Jakub, Jelínek, Tomáš, Pavlíček, Petr, Jungová, Alexandra, Kessler, Petr, Wróbel, Marek, Štork, Martin, Štraub, Jan, Pika, Tomáš, Čápková, Lenka, Ševčíková, Sabina, Maisnar, Vladimír, Hájek, Roman

“…We assessed the outcomes of pomalidomide and dexamethasone treatment in relapsed/refractory multiple myeloma (RRMM) patients with ≥1 prior line of therapy. We…”
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Synergistic digestibility effect by planktonic natural food and habitat renders high digestion efficiency in agastric aquatic consumers by Roy, Koushik, Kajgrova, Lenka, Capkova, Lenka, Zabransky, Lubos, Petraskova, Eva, Dvorak, Petr, Nahlik, Vit, Kuebutornye, Felix Kofi Agbeko, Blabolil, Petr, Blaha, Martin, Vrba, Jaroslav, Mraz, Jan

“…A digestibility enhancing effect of natural food on stomachless fish model (Cyprinus carpio) was verified by fluorogenic substrate assays of enzymatic…”
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SWATH-MS Analysis of FFPE Tissues Identifies Stathmin as a Potential Marker of Endometrial Cancer in Patients Exposed to Tamoxifen by Janacova, Lucia, Faktor, Jakub, Capkova, Lenka, Paralova, Vendula, Pospisilova, Anna, Podhorec, Jan, Ebhardt, Holger Alexander, Hrstka, Roman, Nenutil, Rudolf, Aebersold, Ruedi, Bouchal, Pavel

“…A specific form of endometrial cancer (EC) can develop in breast cancer patients previously treated with tamoxifen (ET), an antagonist of estrogen receptor…”
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Follow-up Analysis of Ixazomib, Lenalidomide and Dexamethasone Versus Lenalidomide and Dexamethasone in Routine Clinical Practice by Minarik, Jiri, Radocha, Jakub, Jungova, Alexandra, Straub, Jan, Jelinek, Tomas, Pika, Tomas, Pour, Ludek, Pavlicek, Petr, Harvanova, Lubica, Capkova, Lenka, Krhovska, Petra, Machalkova, Katerina, Jindra, Pavel, Spicka, Ivan, Plonkova, Hana, Stork, Martin, Mistrik, Martin, Bacovsky, Jaroslav, Maisnar, Vladimir, Hajek, Roman

“…Background: The addition of ixazomib to the doublet lenalidomide and dexamethasone (RD) in relapsed and refractory multiple myeloma (RRMM) has shown…”
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Survival Analysis of Newly Diagnosed Transplant-Eligible Multiple Myeloma Patients in Czech Republic by Popkova, Tereza, Pour, Ludek, Spicka, Ivan, Radocha, Jakub, Jungova, Alexandra, Minarik, Jiri, Jelinek, Tomas, Pavlicek, Petr, Krejci, Marta, Straub, Jan, Maisnar, Vladimir, Dekojova, Tereza, Pika, Tomas, Soukup, Jan, Capkova, Lenka, Hájek, Roman

“…Introduction: Although highly effective agents and novel therapeutic strategies are being developed, high-dose chemotherapy followed by autologous stem cell…”
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Circulating Plasma Cells Are the Most Powerful Prognostic Marker in Transplant Ineligible Multiple Myeloma with 2% As a New Cut-Off for Primary Plasma Cell Leukemia by Jelinek, Tomas, Bezděková, Renata, Zihala, David, Sevcikova, Tereza, Capkova, Lenka, Polackova, Petra, Stork, Martin, Knechtova, Zdenka, Venglar, Ondrej, Jurczyszyn, Artur, Castillo, Jorge J., Penka, Miroslav, Radocha, Jakub, Sevcikova, Sabina, Pour, Ludek, Rihova, Lucie, Hajek, Roman

“…Background: Tumor burden in multiple myeloma (MM) is routinely evaluated in the bone marrow, though its prognostic value is not proven. There is an increasing…”
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Outcomes According to MSKCC Risk Score with Focus on the Intermediate-Risk Group in Metastatic Renal Cell Carcinoma Patients Treated with First-Line Sunitinib: A Retrospective Analysis of 2390 Patients by Fiala, Ondrej, Finek, Jindrich, Poprach, Alexandr, Melichar, Bohuslav, Kopecký, Jindrich, Zemanova, Milada, Kopeckova, Katerina, Mlcoch, Tomas, Dolezal, Tomas, Capkova, Lenka, Buchler, Tomas

“…The Memorial Sloan-Kettering Cancer Center (MSKCC) prognostic model has been widely used for the prediction of the outcome of metastatic renal cell carcinoma…”
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Overall Survival Benefit of Ixazomib, Lenalidomide and Dexamethasone (IRD) over Lenalidomide and Dexamethasone (RD) in RRMM Patients Treated in Routine Clinical Practice: Results from the Czech Registry of Monoclonal Gammopathies (RMG) by Minarik, Jiri, Pika, Tomas, Radocha, Jakub, Jungova, Alexandra, Straub, Jan, Jelinek, Tomas, Pour, Ludek, Pavlicek, Petr, Mistrik, Martin, Brožová, Lucie, Krhovska, Petra, Machalkova, Katerina, Jindra, Pavel, Spicka, Ivan, Plonkova, Hana, Stork, Martin, Bacovsky, Jaroslav, Capkova, Lenka, Sykora, Michal, Kessler, Petr, Stejskal, Lukáš, Heindorfer, Adriana, Ullrychova, Jana, Skacel, Tomas, Maisnar, Vladimir, Hajek, Roman

“…Background: Outcomes reported in real-world practice versus controlled clinical trials show markedly shorter treatment durations, progression free survival…”
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Survival benefit of ixazomib, lenalidomide and dexamethasone in relapsed and refractory multiple myeloma patients in routine clinical practice by Minarik, Jiri, Pika, Tomas, Radocha, Jakub, Jungova, Alexandra, Straub, Jan, Jelinek, Tomas, Pour, Ludek, Pavlicek, Petr, Mistrik, Martin, Brozova, Lucie, Krhovska, Petra, Machalkova, Katerina, Jindra, Pavel, Spicka, Ivan, Plonkova, Hana, Stork, Martin, Bacovsky, Jaroslav, Capkova, Lenka, Sykora, Michal, Kessler, Petr, Stejskal, Lukas, Heindorfer, Adriana, Ullrychova, Jana, Skacel, Tomas, Maisnar, Vladimir, Hajek, Roman

“…We have performed a head to head comparison of all-oral triplet combination of ixazomib, lenalidomide and dexamethasone (IRD) versus lenalidomide and…”
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Closing the Efficacy and Effectiveness Gap: Outcomes in Relapsed/Refractory Multiple Myeloma (RRMM) Patients (Pts) Treated with Ixazomib-Lenalidomide-Dexamethasone (IRd) in Routine Clinical Practice Remain Comparable to the Outcomes Reported in the Phase 3 Tourmaline-MM1 Study by Hajek, Roman, Minarik, Jiri, Straub, Jan, Pour, Ludek, Jungova, Alexandra, Berdeja, Jesus G., Boccadoro, Mario, Brožová, Lucie, Spencer, Andrew, van Rhee, Frits, Vela-Ojeda, Jorge, Thompson, Michael A., Abonour, Rafat, Chari, Ajai, Cook, Gordon, Costello, Caitlin L., Davies, Faith E., Hungria, Vania T.M., Lee, Hans C., Leleu, Xavier, Puig, Noemi, Rifkin, Robert M., Terpos, Evangelos, Usmani, Saad Z., Weisel, Katja C., Zonder, Jeffrey A., Bařinová, Magda, Kuhn, Matyáš, Silar, Jiri, Capkova, Lenka, Galvez, Kenny, Lu, Jin, Skacel, Tomas, Elliott, Jennifer, Demers, Brittany, Stull, Dawn Marie, Ren, Kaili, Maisnar, Vladimir

“…Background Ixazomib, the first oral proteasome inhibitor, has been approved for >3 years in >70 countries, for the treatment of RRMM pts who have received ≥1…”
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Real-world comparison of Ixazomib, lenalidomide and dexamethasone vs lenalidomide and dexamethasone in relapsed and refractory multiple myeloma by Minarik, Jiri, Pika, Tomas, Radocha, Jakub, Jungova, Alexandra, Straub, Jan, Jelinek, Tomas, Pour, Ludek, Pavlicek, Petr, Mistrik, Martin, Brozova, Lucie, Krhovska, Petra, Machalkova, Katerina, Jindra, Pavel, Spicka, Ivan, Plonkova, Hana, Štork, Martin, Bacovsky, Jaroslav, Capkova, Lenka, Sykora, Michal, Kessler, Petr, Stejskal, Lukas, Heindorfer, Adriana, Ullrychova, Jana, Maisnar, Vladimir, Hajek, Roman

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Gene expression-guided selection of histopathology image features by Budinska, Eva, Capkova, Lenka, Schwarz, Daniel, Dusek, Ladislav, Jaggi, Rolf, Feit, Josef, Popovici, Vlad

“…Histopathology imaging and gene expression profiling are two fundamental investigative techniques which allow the analysis of biological specimens from…”
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