Search Results - "Capiglioni, Alejo M."
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Adenoviral Transfer of Human Aquaporin-8 Gene to Mouse Liver Improves Ammonia-Derived Ureagenesis
Published in Cells (Basel, Switzerland) (02-06-2023)“…We previously reported that, in cultured hepatocytes, mitochondrial aquaporin-8 (AQP8) channels facilitate the conversion of ammonia to urea and that the…”
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Data of ureagenesis from ammonia, glutamine and alanine, and mitochondrial aquaporin-8 expression in thioacetamide-treated hepatocytes
Published in Data in brief (01-06-2020)“…We present data about the synthesis of urea from different substrates, i.e., free ammonia, glutamine and alanine in primary cultured rat hepatocytes treated or…”
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Data of H2O2 release from AQP8-knockdown rat hepatocyte mitochondria
Published in Data in brief (01-04-2019)“…This article reports experimental data related to the research article entitled “Mitochondrial aquaporin-8 is involved in SREBP-controlled hepatocyte…”
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Mitochondrial aquaporin-8 is involved in SREBP-controlled hepatocyte cholesterol biosynthesis
Published in Free radical biology & medicine (01-02-2019)“…Cholesterol, via sterol regulatory element-binding protein (SREBP) transcription factors, activates or represses genes involved in its hepatic biosynthetic…”
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Further evidence for the involvement of mitochondrial aquaporin-8 in hepatocyte lipid synthesis
Published in Biochimie (01-09-2021)“…We recently provided evidence suggesting that mitochondrial aquaporin-8 (mtAQP8), a channel protein able to conduct H2O2, is involved in the modulation of…”
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Aquaporin gene transfer for hepatocellular cholestasis
Published in Biochimie (01-09-2021)“…Bile secretion by hepatocytes is an osmotic process. The output of bile salts and other organic anions (e.g. glutathione), through the bile salt transporter…”
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Enhanced ammonia detoxification to urea in hepatocytes transduced with human aquaporin‐8 gene
Published in Biotechnology and bioengineering (01-11-2021)“…Hepatic ammonia detoxification to urea is critical for the prevention of hyperammonemia and neurological damage. Hepatocyte mitochondrial aquaporin‐8 (AQP8)…”
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Hepatic glycerol metabolism is early reprogrammed in rat liver cancer development
Published in Biochimie (01-03-2020)“…Evidence shows that oral glycerol supplementation during the early stages of rat liver cancer reduces the growth of preneoplastic lesions. Besides, human…”
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Cholesterol can modulate mitochondrial aquaporin‐8 expression in human hepatic cells
Published in IUBMB life (01-05-2017)“…Hepatocyte mitochondrial aquaporin‐8 (mtAQP8) works as a multifunctional membrane channel protein that facilitates the uptake of ammonia for its detoxification…”
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Attenuation of liver cancer development by oral glycerol supplementation in the rat
Published in European journal of nutrition (01-04-2018)“…Purpose Glycerol usage is increasing in food industry for human and animal nutrition. This study analyzed the impact of glycerol metabolism when orally…”
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Data of H 2 O 2 release from AQP8-knockdown rat hepatocyte mitochondria
Published in Data in brief (01-04-2019)“…This article reports experimental data related to the research article entitled "Mitochondrial aquaporin-8 is involved in SREBP-controlled hepatocyte…”
Get full text
Journal Article