Search Results - "Capece, Tara"

The Role of Lymphatic Niches in T Cell Differentiation by Capece, Tara, Kim, Minsoo

“…Long-term immunity to many viral and bacterial pathogens requires CD8(+) memory T cell development, and the induction of long-lasting CD8(+) memory T cells…”
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Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment by Kim, Kyun-Do, Bae, Seyeon, Capece, Tara, Nedelkovska, Hristina, de Rubio, Rafael G., Smrcka, Alan V., Jun, Chang-Duk, Jung, Woojin, Park, Byeonghak, Kim, Tae-il, Kim, Minsoo

“…Adoptive cell transfer utilizing tumour-targeting cytotoxic T lymphocytes (CTLs) is one of the most effective immunotherapies against haematological…”
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Regulation of T cell motility in vitro and in vivo by LPA and LPA2 by Knowlden, Sara A, Capece, Tara, Popovic, Milan, Chapman, Timothy J, Rezaee, Fariba, Kim, Minsoo, Georas, Steve N

“…Lysophosphatidic acid (LPA) and the LPA-generating enzyme autotaxin (ATX) have been implicated in lymphocyte trafficking and the regulation of lymphocyte entry…”
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The Role of Lymphatic Niches in T Cell Differentiation by Capece, Tara, Kim, Minsoo

“…Long-term immunity to many viral and bacterial pathogens requires$ CD8^+$ memory T cell development, and the induction of long-lasting$ CD8^+$ memory T cells…”
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Essential role of Elmo1 in Dock2-dependent lymphocyte migration by Stevenson, Catherine, de la Rosa, Gonzalo, Anderson, Christopher S, Murphy, Patrick S, Capece, Tara, Kim, Minsoo, Elliott, Michael R

“…Elmo1 and Elmo2 are highly homologous cytoplasmic adaptor proteins that interact with Dock family guanine nucleotide exchange factors to promote activation of…”
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318 Building A Better CAR: Improving CAR-T Trafficking in Cancer Therapy by Hong, Yeonsun, Kim, Hye-Ran, Walling, Brandon L., Lozada, John, Amitrano, Andrea M., Sailer, Cooper J., Lim, Kihong, Mongre, Raj Kumar, Kim, Kyun-Do, Capece, Tara, Lomakina, Elena B., Reilly, Nicholas S., Waugh, Richard E., Reagan, Patrick M., Kim, Minsoo, Oakes, Patrick W., Jun, Chang-Duk

“…OBJECTIVES/GOALS: #NAME? METHODS/STUDY POPULATION: Cell culture & protein identification: human T cells were purified from healthy blood, then activated &…”
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Neutrophil trails guide influenza-specific CD8+T cells in the airways by Lim, Kihong, Hyun, Young-Min, Lambert-Emo, Kris, Capece, Tara, Bae, Seyeon, Miller, Richard, Topham, David J., Kim, Minsoo

“…During viral infections, chemokines guide activated effector T cells to infection sites. However, the cells responsible for producing these chemokines and how…”
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Chemokine independent T cell migration by Walling, Brandon Lee, Capece, Tara, Kim, Minsoo

“…Abstract Our current understanding of T cell migration is focused on chemokine-mediated integrin activation, which dictates that chemokines provide critical…”
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A novel intracellular pool of LFA-1 is critical for asymmetric CD8 + T cell activation and differentiation by Capece, Tara, Walling, Brandon L, Lim, Kihong, Kim, Kyun-Do, Bae, Seyeon, Chung, Hung-Li, Topham, David J, Kim, Minsoo

“…The integrin lymphocyte function-associated antigen 1 (LFA-1; CD11a/CD18) is a key T cell adhesion receptor that mediates stable interactions with…”
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ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors by Hong, Yeonsun, Walling, Brandon L., Kim, Hye-Ran, Serratelli, William S., Lozada, John R., Sailer, Cooper J., Amitrano, Andrea M., Lim, Kihong, Mongre, Raj Kumar, Kim, Kyun-Do, Capece, Tara, Lomakina, Elena B., Reilly, Nicholas S., Vo, Kevin, Gerber, Scott A., Fan, Tan-Chi, Yu, Alice Lin-Tsing, Oakes, Patrick W., Waugh, Richard E., Jun, Chang-Duk, Reagan, Patrick M., Kim, Minsoo

“…Adoptive transfer of genetically engineered chimeric antigen receptor (CAR) T cells is becoming a promising treatment option for hematological malignancies…”
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Regulation of integrin LFA-1 (CD11a/CD18) during T cell migration and activation (CAM1P.227) by Capece, Tara, Abid, Anna, Kim, Minsoo

“…Abstract T cell entry into a lymph node is dependent upon several events, including activation of chemokine receptor CCR7 and adhesion of integrin LFA1. T…”
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Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites by Gaylo-Moynihan, Alison, Prizant, Hen, Popović, Milan, Fernandes, Ninoshka R.J., Anderson, Christopher S., Chiou, Kevin K., Bell, Hannah, Schrock, Dillon C., Schumacher, Justin, Capece, Tara, Walling, Brandon L., Topham, David J., Miller, Jim, Smrcka, Alan V., Kim, Minsoo, Hughson, Angela, Fowell, Deborah J.

“…T-helper (Th) cell differentiation drives specialized gene programs that dictate effector T cell function at sites of infection. Here, we have shown Th cell…”
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Optical control of Calcium influx improves intratumoral cytotoxic T lymphocyte effector functions by Kim, Kyun Do, Bae, Seyeon, Nedelkovska, Hristina, Capece, Tara, Kim, Minsoo

“…Abstract Regulatory T cells (Tregs) have critical roles in the maintenance of immunological self-tolerance and in the control of antitumor immune responses. In…”
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Asymmetric integrin segregation regulates CD8+ T cell fate during cell division by Capece, Tara, Walling, Brandon Lee, Hyun, Young-Min, Kim, Tae-Hyoun, Lim, Kihong, Kim, Minsoo

“…Abstract Recent evidence suggests lineage commitment of effector and memory T cells occurs as early as the first T cell division, using the evolutionarily…”
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Programming of distinct chemokine-dependent and -independent search strategies for T helper-1 and Th2 cells optimizes function at inflamed sites by Gaylo-Moynihan, Alison, Prizant, Hen, Popović, Milan, Fernandes, Ninoshka R.J., Anderson, Christopher, Chiou, Kevin K., Bell, Hannah, Schrock, Dillon C., Schumacher, Justin, Capece, Tara, Walling, Brandon, Topham, David J., Miller, Jim, Smrcka, Alan, Kim, Minsoo, Hughson, Angela, Fowell, Deborah J

“…T-helper (Th) cell differentiation drives specialized gene programs that dictate effector T cell function at sites of infection. Here we have shown Th cell…”
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Dynamic regulation of LFA-1 and Mac-1 during neutrophil extravasation in live mice (CAM1P.232) by Hyun, Young-Min, Capece, Tara, Lim, Kihong, Wong, Jennifer, Kim, Minsoo

“…Abstract LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) are key integrins that regulate leukocyte adhesion and migration in inflamed tissues. Despite considerable…”
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Essential role of elmo1 in dock2-dependent lymphocyte migration (CAM1P.228) by de la Rosa, Gonzalo, Stevenson, Catherine, Anderson, Christopher, Murphy, Patrick, Capece, Tara, Kim, Minsoo, Elliott, Michael

“…Abstract Elmo1 and Elmo2 are highly homologous cytoplasmic adapter proteins that interact with Dock family guanine nucleotide exchange factors to promote…”
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Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumor microenvironment by Kim, Kyun Do, Bae, Seyeon, Capece, Tara, Nedelkovska, Hristina, de Rubio, Rafael G, Smrcka, Alan V, Jung, Woojin, Park, Byeonghak, Kim, Tae-il, Srikanth, Sonal, Gwack, Yousang, Kim, Minsoo

“…Abstract Adoptive cell transfer utilizing tumor-targeting cytotoxic T lymphocytes (CTLs) is one of the most effective immunotherapies against hematological…”
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The Role of Integrin LFA-1 in CD8+ T cell Activation and Cell Fate by Capece, Tara

“…Successful development of T cell effector function and long-lasting immune memory requires a prolonged interaction with antigen presenting cells upon cognate…”
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LPA and autotaxin regulate T cell migration and homing (P5095) by Knowlden, Sara, Chapman, Timothy, Emo, Jason, Rezaee, Fariba, Capece, Tara, Kim, Minsoo, Georas, Steve

“…Abstract Lysophosphatidic acid (LPA) has been suggested to regulate lymphocyte entry into lymph nodes because autotaxin (ATX), the enzyme that generates LPA,…”
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