Search Results - "Caparon, Maire H."

Integrated solution to purification challenges in the manufacture of a soluble recombinant protein in E. coli by Caparon, Maire H, Rust, Kevin J, Hunter, Alan K, McLaughlin, Joseph K, Thomas, Kristen E, Herberg, John T, Shell, Robert E, Lanter, Paul B, Bishop, Bruce F, Dufield, Robert L, Wang, Xing, Ho, Sa V

“…Apolipoprotein A 1 Milano (ApoA-1M), the protein component of a high-density lipoprotein (HDL) mimic with promising potential for reduction of atherosclerotic…”
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Saturation Mutagenesis of Human Interleukin-3 (∗) by Olins, Peter O., Bauer, S. Christopher, Braford-Goldberg, Sarah, Sterbenz, Kris, Polazzi, Joseph O., Caparon, Maire H., Klein, Barbara K., Easton, Alan M., Paik, Kumnan, Klover, Jon A., Thiele, Barrett R., McKearn, John P.

“…A deletion variant of human interleukin-3, hIL-315-125, was produced in the periplasmic space of Escherichia coli and had full activity in an AML193.1.3 cell…”
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Use of combinatorial mutagenesis to select for multiply substituted human interleukin-3 variants with improved pharmacologic properties by Klein, Barbara K., Olins, Peter O., Bauer, S.Christopher, Caparon, Maire H., Easton, Alan M., Braford, Sarah R., Abrams, Mark A., Klover, Jon A., Paik, Kumnan, Thomas, John W., Hood, William F., Shieh, Jeng-Jong, Polazzi, Joseph O., Donnelly, Ann M., Zeng, David L., Welply, Joseph K., McKearn, John P.

“…A combinatorial mutagenesis strategy was used to create a collection of nearly 500 variants of human interleukin 3 (IL-3), each with four to nine amino acid…”
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Analysis of novel streptavidin-binding peptides, identified using a phage display library, shows that amino acids external to a perfectly conserved consensus sequence and to the presented peptides contribute to binding by Caparon, M H, De Ciechi, P A, Devine, C S, Olins, P O, Lee, S C

“…Streptavidin-binding peptides containing the consensus amino acid sequence motif EPDW were identified using a phage display library. Phage presenting peptides…”
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