Search Results - "Capan, Y"

pH-sensitive chitosan-PEG-decorated hollow mesoporous silica nanoparticles could be an effective treatment for acute myeloid leukemia (AML) by Ultav, G., Tonbul, H., Tavukcuoglu, E., Ozturk, S. C., Akbas, S., Sahin, A., Esendagli, G., Capan, Y.

“…Improved treatment of acute myeloid leukemia (AML) could be possible by longer retention of anticancer drugs in the bloodstream. In this study, it was aimed to…”
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Simultaneous Determination of Dexpanthenol, Lidocaine Hydrochloride, Mepyramine Maleate and their Related Substances by a RP-HPLC Method in Topical Dosage Forms by Doganay, A, Koksel, B, Gundogdu, S O, Capan, Y

“…Abstract The pharmaceutical combination of dexpanthenol (DPA), lidocaine hydrochloride (LIH) and mepyramine maleate (MAM) is used for their anti-allergic,…”
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Characterization of bevacizumab by dynamic light scattering while maintaining its native structure by Akbas, S, Sahin, A, Calis, S, Oncel, H, Capan, Y

“…Bevacizumab, is a humanized monoclonal antibody and patents on Avastin® (Bevacizumab, Roche) will expire in the US in 2019 and in Europe in 2022. Therefore,…”
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Counterfeit/Copy Drugs: Patients Safety in the Heart by Capan, Y.

“…Some studies demonstrate that a large proportion of copy drugs contain lower levels of active substances and higher impurity levels than reference drugs. The…”
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An aquaporin 4 antisense oligonucleotide loaded, brain targeted nanoparticulate system design by Kozlu, S, Caban, S, Yerlikaya, F, Fernandez-Megia, E, Novoa-Carballal, R, Riguera, R, Yemisci, M, Gursoy-Ozdemir, Y, Dalkara, T, Couvreur, P, Capan, Y

“…Aquaporins (AQPs), members of the water-channel protein family, are highly expressed in brain tissue especially in astrocytic end-feet. They are important…”
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Formulation and evaluation of clozapine orally disintegrating tablets prepared by direct compression by Olmez, S S, Vural, I, Sahin, S, Ertugrul, A, Capan, Y

“…In this study, clozapine orally disintegrating tablets (ODTs) were prepared by direct compression method. Disintegration time, resistance to crushing of…”
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The influence of technological parameters on the physicochemical properties of blank PLGA nanoparticles by Ozturk, K, Caban, S, Kozlu, S, Kadayifci, E, Yerlikaya, F, Capan, Y

“…In this work, PLGA nanoparticles were prepared by an emulsification-diffusion technique. The main objective was to optimize the preparation of formulations by…”
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Comparative in vitro studies on PBN loaded nanoparticles prepared by biodegradable chitosan, PLGA polymers and their PEGylated block copolymers by Ozturk, K., Fernandez-Megia, E., Novoa-Carballal, R., Riguera, R., Yemisci, M., Gursoy-Ozdemir, Y., Dalkara, T., Couvreur, P., Capan, Y.

“…α-phenyl-N-tert-butyl nitrone (PBN) is a neuroprotective free radical scavenger however it has low in vivo stability and blood residence time. Aim. of this…”
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Comparative evaluation of in vitro parameters of tamoxifen citrate loaded poly(lactide-co-glycolide), poly(epsilon-caprolactone) and chitosan nanoparticles by Cirpanli, Y, Yerlikaya, F, Ozturk, K, Erdogar, N, Launay, M, Gegu, C, Leturgez, T, Bilensoy, E, Calis, S, Capan, Y

“…Tamoxifen (TAM), the clinical choice for the antiestrogen treatment of advanced or metastatic breast cancer, was formulated in nanoparticulate carrier systems…”
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Preparation and evaluation of alpha-phenyl-n-tert-butyl nitrone (PBN)-encapsulated chitosan and PEGylated chitosan nanoparticles by Pinarbasli, O, Aktas, Y, Dalkara, T, Andrieux, K, Alonso, M J, Fernandez-Megia, E, Novoa-Carballal, R, Riguera, R, Couvreur, P, Capan, Y

“…Alpha-phenyl-n-tert-butyl nitrone (PBN) shows its major effect by scavenging free radicals formed in the ischemia and it has the ability to penetrate through…”
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Preparation and characterization of PLGA nanospheres for the targeted delivery of NR2B-specific antisense oligonucleotides to the NMDA receptors in the brain by Kilic, A. C., Capan, Y., Vural, I., Gursoy, R. N., Dalkara, T., Cuine, A., Hincal, A. A.

“…Treatment of central nervous system (CNS) diseases with potentially useful pharmaceuticals is prevented by the blood-brain barrier (BBB). The BBB is a unique…”
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Formulation and in vitro-in vivo evaluation of buccoadhesive morphine sulfate tablets by ANLAR, S, CAPAN, Y, GÜVEN, O, GÖGÜS, A, DALKARA, T, HINCAL, A. A

“…Buccoadhesive controlled-release systems for the delivery of morphine sulfate were prepared by compression of hydroxypropyl methylcellulose (HPMC) with…”
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In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine by Ikinci, G, Capan, Y, Senel, S, Alaaddinoğlu, E, Dalkara, T, Hincal, A A

“…A buccoadhesive controlled-release system for delivery of carbamazepine (CBZ) was prepared by compression of hydroxypropyl methylcellulose (HPMC) and carbomer,…”
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Development and evaluation of paclitaxel nanoparticles using a quality-by-design approach by Yerlikaya, Firat, Ozgen, Aysegul, Vural, Imran, Guven, Olgun, Karaagaoglu, Ergun, Khan, Mansoor A, Capan, Yilmaz

“…The aims of this study were to develop and characterize paclitaxel nanoparticles, to identify and control critical sources of variability in the process, and…”
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Preparation and characterization of bFGF and BSA-loaded microspheres by Cetin, M., Capan, Y., Vural, I., Dogan, A.L., Guc, D., Hincal, A.A., Wehrlé, P., Dalkara, T.

“…This article describes the preparation and characterization of BSA and bFGF-loaded PLGA microspheres and assesses the effect of entrapment procedure and in…”
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Bacterial translocation in experimental intestinal obstruction by Akçay, M N, Capan, M Y, Gündogdu, C, Polat, M, Oren, D

“…In this study, bacterial translocation to the mesenteric lymph nodes (MLN), liver and spleen and the histopathological changes in the intestine MLN, liver and…”
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Development and Brain Delivery of Chitosan−PEG Nanoparticles Functionalized with the Monoclonal Antibody OX26 by Aktaş, Yeşim, Yemisci, Muge, Andrieux, Karine, Gürsoy, R. Neslihan, Alonso, Maria Jose, Fernandez-Megia, Eduardo, Novoa-Carballal, Ramón, Quiñoá, Emilio, Riguera, Ricardo, Sargon, Mustafa F, Çelik, H. Hamdi, Demir, Ayhan S, Hıncal, A. Atilla, Dalkara, Turgay, Çapan, Yılmaz, Couvreur, Patrick

“…The inhibition of the caspase-3 enzyme is reported to increase neuronal cell survival following cerebral ischemia. The peptide Z-DEVD-FMK is a specific caspase…”
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Formulation and in vitro/in vivo investigation of carbamazepine controlled-release matrix tablets by Ikinci, G, Capan, Y, Senel, S, Dalkara, T, Hincal, A A

“…Carbamazepine controlled-release tablet formulations containing hydroxypropyl methylcellulose (HPMC) as matrix material at different concentrations were…”
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Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor by Aktaş, Yeşim, Andrieux, Karine, Alonso, Maria Jose, Calvo, Pilar, Gürsoy, R. Neslihan, Couvreur, Patrick, Çapan, Yılmaz

“…The aim of this work was to develop a formulation for Z-DEVD-FMK, a peptide which is a caspase inhibitor and has been used in experimental animal studies for a…”
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Microbiological and clinical comparison of chlorhexidine buccoadhesive tablet and chlorhexidine mouthrinse by Aktaş, A., Giray, B., Çapan, Y., Menemenlioğlu, D., Hayran, M., İkinci, G., Vural, İ.

“…Chlorhexidine, which is a gold standard for antiplaque agents, was prepared as a buccoadhesive controlled-release drug formulation. The released amount and…”
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