Search Results - "Cao, Ziyang"
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Bioorthogonal in situ assembly of nanomedicines as drug depots for extracellular drug delivery
Published in Nature communications (19-04-2022)“…Developing precise nanomedicines to improve the transport of anticancer drugs into tumor tissue and to the final action site remains a critical challenge…”
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2
Investigation of the Effect Mechanism of Cutting Sequence on Spiral Milling of CFRP/Ti Laminates Under Ultrasonic-Assisted Conditions
Published in International journal of precision engineering and manufacturing (01-04-2024)“…The hole-making mechanism of carbon fiber reinforced plastic (CFRP)/titanium alloy stacks is different from that of monolayer materials. In order to reveal the…”
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3
Magnetically Actuated Active Deep Tumor Penetration of Deformable Large Nanocarriers for Enhanced Cancer Therapy
Published in Advanced functional materials (01-08-2021)“…The intrinsic pathological microenvironment of tumor tissue enforces barriers to the passive diffusion of nanomedicine, which results in inefficient tumor…”
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Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion
Published in Proceedings of the National Academy of Sciences - PNAS (22-07-2014)“…In mammalian cells, tumor suppressor p53 plays critical roles in the regulation of glucose metabolism, including glycolysis and oxidative phosphorylation, but…”
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Roles of the Indo-Pacific subsurface Kelvin waves and volume transport in prolonging the triple-dip 2020–2023 La Niña
Published in Environmental research letters (01-10-2023)“…Abstract The rare triple-dip 2020–2023 La Niña event has resulted in a series of extreme climate events across the globe. Here, we reveal the role of tropical…”
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ROS-Activatable siRNA-Engineered Polyplex for NIR-Triggered Synergistic Cancer Treatment
Published in ACS applied materials & interfaces (22-07-2020)“…Small interfering RNA (siRNA) shows excellent pharmaceutical prospects in treating diverse life-threatening diseases. Photodynamic therapy (PDT) is a…”
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Deformable nanocarriers for enhanced drug delivery and cancer therapy
Published in Exploration (Beijing, China) (01-10-2024)“…Recently, the field of nanomedicine has witnessed substantial advancements in the development of nanocarriers for targeted drug delivery, emerges as promising…”
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Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis
Published in The Journal of biological chemistry (11-08-2017)“…Sirtuin 7 (SIRT7), a member of the NAD+-dependent class III histone deacetylases, is involved in the regulation of various cellular processes and in resisting…”
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Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles
Published in Frontiers in pharmacology (01-11-2024)“…Colorectal cancer (CRC) stands as the third most widespread cancer globally with poor prognosis. Berberine (Ber), as one herbal phytochemical, showed promise…”
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Using droplet digital PCR in the detection of Mycobacterium tuberculosis DNA in FFPE samples
Published in International journal of infectious diseases (01-10-2020)“…•Droplet digital PCR (ddPCR) showed greatly improved sensitivity over real-time PCR for detecting Mycobacterium tuberculosis (MTB) in formalin-fixed and…”
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Electrochemical method for large size and few-layered water-dispersible graphene
Published in Carbon (New York) (01-03-2019)“…We propose an electrochemical route that can prepare few-layered water-dispersible graphene (W-Gr) ≤ 6 atomic layers in thickness and 1–50 μm in lateral size…”
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12
Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damage
Published in Nucleic acids research (06-09-2018)“…Abstract Linker histone H1 has a key role in maintaining higher order chromatin structure and genome stability, but how H1 functions in these processes is…”
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Psychological Impact of the 2022 Round COVID-19 Pandemic on China’s College Students
Published in Shanghai jiao tong da xue xue bao (01-02-2024)“…In response to the new round of COVID-19 outbreaks since March 2022, universities with high outbreak rates around the country have taken quarantine measures to…”
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SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair
Published in Science advances (01-03-2019)“…The activation of ataxia-telangiectasia mutated (ATM) upon DNA damage involves a cascade of reactions, including acetylation by TIP60 and autophosphorylation…”
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Multi-omics integration reveals a six-malignant cell maker gene signature for predicting prognosis in high-risk neuroblastoma
Published in Frontiers in neuroinformatics (10-11-2022)“…Background Neuroblastoma is the most common extracranial solid tumor of childhood, arising from the sympathetic nervous system. High-risk neuroblastoma (HRNB)…”
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A Magnetically Driven Amoeba‐Like Nanorobot for Whole‐Process Active Drug Transport
Published in Advanced science (01-03-2023)“…The passive diffusion performance of nanocarriers results in inefficient drug transport across multiple biological barriers and consequently cancer therapy…”
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Enhancement of chemosensitivity by WEE1 inhibition in EGFR-TKIs resistant non-small cell lung cancer
Published in Biomedicine & pharmacotherapy (01-09-2019)“…Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) is the first-line treatment in non-resectable non-small lung cancer (NSCLC) with EGFR…”
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Comparison of the SuperARMS and ARMS for detecting EGFR mutations in liquid-based cytology specimens from NSCLC patients
Published in Diagnostic pathology (31-01-2020)“…Non-surgical cytological specimens are adequate not only for accurate histological subtyping but also for molecular profiling. A modified amplification…”
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Multi-omics integration reveals potential stage-specific druggable targets in T-cell acute lymphoblastic leukemia
Published in Genes & diseases (01-09-2024)“…T-cell acute lymphoblastic leukemia (T-ALL), a heterogeneous hematological malignancy, is caused by the developmental arrest of normal T-cell progenitors. The…”
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Super enhancers: Pathogenic roles and potential therapeutic targets for acute myeloid leukemia (AML)
Published in Genes & diseases (01-11-2022)“…Acute myeloid leukemia (AML) is a malignant hematological tumor with disordered oncogenes/tumor suppressor genes and limited treatments. The potent anti-cancer…”
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