Search Results - "Cao, Xuetao"

COVID-19: immunopathology and its implications for therapy by Cao, Xuetao

“…Severe coronavirus disease 2019 (COVID-19) is characterized by pneumonia, lymphopenia, exhausted lymphocytes and a cytokine storm. Significant antibody…”
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ISG15 secretion exacerbates inflammation in SARS-CoV-2 infection by Cao, Xuetao

“…Conjugation of the ubiquitin-like protein ISG15 to targets (ISGylation) benefits antiviral defense. However, SARS-CoV-2 induces human macrophages to…”
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Epigenetic regulation of the innate immune response to infection by Zhang, Qian, Cao, Xuetao

“…Innate immune cells have complex signalling pathways for sensing pathogens and initiating innate immune responses against infection. These pathways are tightly…”
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Characteristics and Significance of the Pre-metastatic Niche by Liu, Yang, Cao, Xuetao

“…Primary tumors create a favorable microenvironment, namely, pre-metastatic niche, in secondary organs and tissue sites for subsequent metastases. The…”
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Dendritic cell migration in inflammation and immunity by Liu, Juan, Zhang, Xiaomin, Cheng, Yujie, Cao, Xuetao

“…Dendritic cells (DCs) are the key link between innate immunity and adaptive immunity and play crucial roles in both the promotion of immune defense and the…”
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An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism by Wang, Pin, Xu, Junfang, Wang, Yujia, Cao, Xuetao

“…Viruses regulate host metabolic networks to improve their survival. The molecules that are responsive to viral infection and regulate such metabolic changes…”
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Intestinal inflammation induced by oral bacteria by Cao, Xuetao

“…Colonization of intestine by oral bacteria can induce inflammatory disorders Numerous microorganisms, including bacteria, colonize the intestine where they…”
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Epigenetic Remodeling in Innate Immunity and Inflammation by Zhang, Qian, Cao, Xuetao

“…The innate immune response is a rapid response to pathogens or danger signals. It is precisely activated not only to efficiently eliminate pathogens but also…”
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Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses by Wang, Lei, Wen, Mingyue, Cao, Xuetao

“…DNA viruses typically eject genomic DNA into the nuclei of host cells after entry. It is unclear, however, how nuclear pathogen-derived DNA triggers innate…”
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Post-Translational Modification Control of Innate Immunity by Liu, Juan, Qian, Cheng, Cao, Xuetao

“…A coordinated balance between the positive and negative regulation of pattern-recognition receptor (PRR)-initiated innate inflammatory responses is required to…”
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The origin and function of tumor-associated macrophages by Liu, Yang, Cao, Xuetao

“…Identifying the cellular and molecular suppressors of the immune response against tumors is a popular topic in the field of tumor immunology that will provide…”
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Regulation of type I interferon signaling in immunity and inflammation: A comprehensive review by Chen, Kun, Liu, Juan, Cao, Xuetao

“…Abstract Type I interferons (IFNs) play essential roles in establishing and modulating host defense against microbial infection via induction of IFN-stimulated…”
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The function and regulation of TET2 in innate immunity and inflammation by Cong, Boyi, Zhang, Qian, Cao, Xuetao

“…TET2, a member of ten-eleven translocation (TET) family as α-ketoglutarate- and Fe 2+-dependent dioxygenase catalyzing the iterative oxidation of…”
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Organotropic metastasis： role of tumor exosomes by Liu, Yang, Cao, Xuetao

“…A recent paper in Nature shows that tumor exosomes expressing unique integrins can determine or- ganotropic metastasis by preparing pre-metastatic niche…”
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Cellular and molecular regulation of innate inflammatory responses by Liu, Juan, Cao, Xuetao

“…Innate sensing of pathogens by pattern-recognition receptors （PRRs） plays essential roles in the innate discrimination between self and non-self components,…”
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Long noncoding RNAs in innate immunity by Zhang, Yuan, Cao, Xuetao

“…Long noncoding RNAs （IncRNAs） have been shown to play important roles in immune cell development and immune responses through different mechanisms, such as…”
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Nuclear innate sensors for nucleic acids in immunity and inflammation by Lin, Hongyu, Cao, Xuetao

“…Innate sensors recognize pathogen‐associated molecular patterns (PAMPs) or damage‐associated molecular patterns (DAMPs) to initiate innate immune response by…”
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The immune potential and immunopathology of cytokine-producing B cell subsets: A comprehensive review by Bao, Yan, Cao, Xuetao

“…Abstract B lymphocytes are generally recognized for their potential to mediate humoral immunity by producing different antibody isotypes and being involved in…”
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Regulation of Toll-like receptor signaling pathways in innate immune responses by Qian, Cheng, Cao, Xuetao

“…Toll‐like receptors (TLRs) are critical pattern recognition receptors (PRRs) that recognize pathogen‐associated molecular patterns (PAMPs), which are conserved…”
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The long noncoding RNA Lnczc3h7a promotes a TRIM25-mediated RIG-I antiviral innate immune response by Lin, Hongyu, Jiang, Minghong, Liu, Lun, Yang, Zongheng, Ma, Zhongfei, Liu, Shuo, Ma, Yuanwu, Zhang, Lianfeng, Cao, Xuetao

“…The helicase RIG-I initiates an antiviral immune response after recognition of pathogenic RNA. TRIM25, an E3 ubiquitin ligase, mediates K63-linked…”
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