Search Results - "Cao, Weiya"

hGC33-Modified and Sorafenib-Loaded Nanoparticles have a Synergistic Anti-Hepatoma Effect by Inhibiting Wnt Signaling Pathway by Shen, Jing, Cai, Wenpeng, Ma, Yongfang, Xu, Ruyue, Huo, Zhen, Song, Li, Qiu, Xinyin, Zhang, Yinci, Li, Amin, Cao, Weiya, Zhou, Shuping, Tang, Xiaolong

“…Delivery of tumor-specific inhibitors is a challenge in cancer treatment. Antibody-modified nanoparticles can deliver their loaded drugs to tumor cells that…”
Get full text

Discovery of Novel Mono-Carbonyl Curcumin Derivatives as Potential Anti-Hepatoma Agents by Cao, Weiya, Yu, Pan, Yang, Shilong, Li, Zheyu, Zhang, Qixuan, Liu, Zengge, Li, Hongzhuo

“…Curcumin possesses a wide spectrum of liver cancer inhibition effects, yet it has chemical instability and poor metabolic properties as a drug candidate. To…”
Get full text

The PI3K/mTOR dual inhibitor BEZ235 nanoparticles improve radiosensitization of hepatoma cells through apoptosis and regulation DNA repair pathway by Tang, Xiaolong, Li, Amin, Xie, Chunmei, Zhang, Yinci, Liu, Xueke, Xie, Yinghai, Wu, Binquan, Zhou, Shuping, Huang, Xudong, Ma, Yongfang, Cao, Weiya, Xu, Ruyue, Shen, Jing, Huo, Zhen, Cai, Shuyu, Liang, Yong, Ma, Dong

“…Polymer materials encapsulating drugs have broad prospects for drug delivery. We evaluated the effectiveness of polyethylene glycol-poly (lactic-co-glycolic…”
Get full text

The effects of coal dust exposure on DNA damage and repair of human bronchial epithelial cells by Li, Amin, Zhang, Yinci, Ma, Yongfang, Xu, Ruyue, Song, Li, Cao, Weiya, Tang, Xiaolong

“…To explore the effects of coal dust exposure on DNA damage and repair, human bronchial epithelial BEAS-2B cells were exposed to coal dust and the cellular…”
Get full text

Design, Synthesis, and Antitumor Evaluation of Novel Mono-Carbonyl Curcumin Analogs in Hepatocellular Carcinoma Cell by Yu, Pan, Cao, Weiya, Zhao, Linguo, Han, Qing, Yang, Shilong, Yang, Kepeng, Pan, Xiaolei, Wang, Qianyun, Wang, Yuan

“…Curcumin is a polyphenolic natural product that has promising anticancer properties. However, its clinical utility is limited by its chemical instability and…”
Get full text

Retraction Note: The PI3K/mTOR Dual Inhibitor BEZ235 Nanoparticles Improve Radiosensitization of Hepatoma Cells Through Apoptosis and Regulation DNA Repair Pathway by Tang, Xiaolong, Li, Amin, Xie, Chunmei, Zhang, Yinci, Liu, Xueke, Xie, Yinghai, Wu, Binquan, Zhou, Shuping, Huang, Xudong, Ma, Yongfang, Cao, Weiya, Xu, Ruyue, Shen, Jing, Huo, Zhen, Cai, Shuyu, Liang, Yong, Ma, Dong

Get full text

Gefitinib sensitization of cisplatin-resistant wild-type EGFR non-small cell lung cancer cells by Li, Amin, Cao, Weiya, Liu, Xueke, Zhang, Yinci, Ma, Yongfang, Xu, Ruyue, Zhang, Rongbo, Liu, Xinkuang, Zhou, Shuping, Wang, Ruikai, Liu, Jiachang, Tang, Xiaolong

“…Purpose The usual first-line strategy of wild-type EGFR (wtEGFR) non-small cell lung cancer (NSCLC) remains cisplatin-based chemotherapy. However, cisplatin…”
Get full text

Coal dust exposure induces proliferation and migration of human bronchial epithelial cells by Li, Amin, Zhang, Yinci, Wang, Ruikai, Xu, Ruyue, Ma, Yongfang, Song, Li, Cao, Weiya, Tang, Xiaolong

“…Background Coal dust exposure has caused a variety of lung diseases. In addition to genotoxicity and cytotoxicity, other biological changes caused by coal dust…”
Get full text

RETRACTED ARTICLE: The PI3K/mTOR dual inhibitor BEZ235 nanoparticles improve radiosensitization of hepatoma cells through apoptosis and regulation DNA repair pathway by Tang, Xiaolong, Li, Amin, Xie, Chunmei, Zhang, Yinci, Liu, Xueke, Xie, Yinghai, Wu, Binquan, Zhou, Shuping, Huang, Xudong, Ma, Yongfang, Cao, Weiya, Xu, Ruyue, Shen, Jing, Huo, Zhen, Cai, Shuyu, Liang, Yong, Ma, Dong

“…Polymer materials encapsulating drugs have broad prospects for drug delivery. We evaluated the effectiveness of polyethylene glycol-poly (lactic-co-glycolic…”
Get full text

An overview of autophagy: Mechanism, regulation and research progress by Cao, Weiya, Li, Jinhong, Yang, Kepeng, Cao, Dongli

“…Autophagy refers to the formation of autophagosomes by membrane wrapping part of the cytoplasm and the organelles and proteins that need to be degraded in the…”
Get full text

Dynamics simulation and in vitro studies of betulinic acid derivative with liver X receptor by Yu, Pan, Cao, Weiya, Wang, Yuan

“…Molecular dynamics simulation of the dominant conformational conjugate was performed for 40 ns and 100 ns via Amber software based on molecular docking by…”
Get full text

Aflatoxin B1: metabolism, toxicology, and its involvement in oxidative stress and cancer development by Cao, Weiya, Yu, Pan, Yang, KePeng, Cao, Dongli

“…Aflatoxins are a class of carcinogenic mycotoxins produced by Aspergillus fungi, which are widely distributed in nature. Aflatoxin B1 (AFB1) is the most toxic…”
Get full text

Design, synthesis and antitumor evaluation of novel quinazoline analogs in hepatocellular carcinoma cell by Yu, Pan, Cao, Weiya, Yang, Shilong, Wang, Yuan, Xia, Aixin, Tan, Xinlan, Wang, Luyi

“…•Five kinds of novel quinazoline analogs were designed by scaffold shopping and synthesized.•Compound D2 (IC50 = 4.06 µM) showed higher anti-HCC activity than…”
Get full text

A7, A Novel Analog of Curcumin, Induces Cell Apoptosis Through Suppressing TGF-βR/MEK/ERK Pathway in A549 Cells by Yu, Pan, Cao, Weiya, Tang, Qianli, Yan, Ruiqing, Tan, Xinlan, Li, Zheyu

“…Lung cancer is the leading cause of cancer death worldwide and curcumin is a natural polyphenol product with a diversity of antitumor activities. However, its…”
Get full text

Autophagy up-regulated by MEK/ERK promotes the repair of DNA damage caused by aflatoxin B1 by Cao, Weiya, Gao, Jiafeng, Zhang, Yinci, Li, Amin, Yu, Pan, Cao, Niandie, Liang, Jiaojiao, Tang, Xiaolong

“…Aflatoxin B1 (AFB1), a kind of mycotoxin, exerts its cytotoxicity by increasing the oxidative damage of target organs, especially the liver. In vivo and…”
Get full text

BEZ235 Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib by Inhibiting PI3K/AKT/mTOR and Inducing Autophagy by Cao, Weiya, Liu, Xueke, Zhang, Yinci, Li, Amin, Xie, Yinghai, Zhou, Shuping, Song, Li, Xu, Ruyue, Ma, Yongfang, Cai, Shiyu, Tang, Xiaolong

“…Acquired resistance of hepatocellular carcinoma (HCC) to sorafenib (SFB) is the main reason for the failure of SFB treatment of the cancer. Abnormal activation…”
Get full text

LY‑294002 enhances the chemosensitivity of liver cancer to oxaliplatin by blocking the PI3K/AKT/HIF‑1α pathway by Xu, Ruyue, Zhang, Yinci, Li, Amin, Ma, Yongfang, Cai, Wenpeng, Song, Li, Xie, Yinghai, Zhou, Shuping, Cao, Weiya, Tang, Xiaolong

“…Liver cancer remains one of the leading causes of cancer deaths worldwide. The therapeutic effect of oxaliplatin on liver cancer is often limited by acquired…”
Get full text

Curcumin reverses hepatic epithelial mesenchymal transition induced by trichloroethylene by inhibiting IL-6R/STAT3 by Cao, Weiya, Zhang, Yinci, Li, Amin, Yu, Pan, Song, Li, Liang, Jiaojiao, Cao, Niandie, Gao, Jiafeng, Xu, Ruyue, Ma, Yongfang, Tang, Xiaolong

“…Epithelial mesenchymal transition (EMT) and inflammation have been identified as carcinogenic agents. This study aims to investigate whether inhibition of…”
Get full text

PKI-587 enhances chemosensitivity of oxaliplatin in hepatocellular carcinoma through suppressing DNA damage repair pathway (NHEJ and HR) and PI3K/AKT/mTOR pathway by Zhang, Yinci, Xie, Chunmei, Li, Amin, Liu, Xueke, Xing, Yingru, Shen, Jing, Huo, Zhen, Zhou, Shuping, Liu, Xinkuang, Xie, Yinghai, Cao, Weiya, Ma, Yongfang, Xu, Ruyue, Cai, Shiyu, Tang, Xiaolong, Ma, Dong

“…Oxaliplatin resistance limits its effectiveness in the treatment of hepatocellular carcinoma (HCC). Abnormal activation of the PI3K/AKT/mTOR pathway has been…”
Get full text

BEZ235 increases sorafenib inhibition of hepatocellular carcinoma cells by suppressing the PI3K/AKT/mTOR pathway by Li, Amin, Zhang, Rongbo, Zhang, Yinci, Liu, Xueke, Wang, Ruikai, Liu, Jiachang, Liu, Xinkuang, Xie, Yinghai, Cao, Weiya, Xu, Ruyue, Ma, Yongfang, Cai, Wenpeng, Wu, Binquan, Cai, Shuyu, Tang, Xiaolong

“…BACKGROUNDSorafenib is an oral multi-kinase inhibitor that inhibits hepatocellular carcinoma (HCC) via the Ras/Raf/MAPK pathway. However, sorafenib loses…”
Get full text