Search Results - "Cao, Manqiu"
-
1
Analytical validation of the Percepta genomic sequencing classifier; an RNA next generation sequencing assay for the assessment of Lung Cancer risk of suspicious pulmonary nodules
Published in BMC cancer (13-04-2021)“…Bronchoscopy is a common procedure used for evaluation of suspicious lung nodules, but the low diagnostic sensitivity of bronchoscopy often results in…”
Get full text
Journal Article -
2
Oligonucleotide Microarray Analysis of Genomic Imbalance in Children with Mental Retardation
Published in American journal of human genetics (01-09-2006)“…The cause of mental retardation in one-third to one-half of all affected individuals is unknown. Microscopically detectable chromosomal abnormalities are the…”
Get full text
Journal Article -
3
Composite Organic−Inorganic Nanoparticles as Raman Labels for Tissue Analysis
Published in Nano letters (01-02-2007)“…Composite organic−inorganic nanoparticles (COINs) are novel optical labels for detection of biomolecules. We have previously developed methods to encapsulate…”
Get full text
Journal Article -
4
Large-scale genotyping of complex DNA
Published in Nature biotechnology (01-10-2003)“…Genetic studies aimed at understanding the molecular basis of complex human phenotypes require the genotyping of many thousands of single-nucleotide…”
Get full text
Journal Article -
5
Whole-Genome Scan, in a Complex Disease, Using 11,245 Single-Nucleotide Polymorphisms: Comparison with Microsatellites
Published in American journal of human genetics (01-07-2004)“…Despite the theoretical evidence of the utility of single-nucleotide polymorphisms (SNPs) for linkage analysis, no whole-genome scans of a complex disease have…”
Get full text
Journal Article -
6
Analytical performance of Envisia: a genomic classifier for usual interstitial pneumonia
Published in BMC pulmonary medicine (17-11-2017)“…Clinical guidelines specify that diagnosis of interstitial pulmonary fibrosis (IPF) requires identification of usual interstitial pneumonia (UIP) pattern…”
Get full text
Journal Article -
7
High-Resolution Identification of Chromosomal Abnormalities Using Oligonucleotide Arrays Containing 116,204 SNPs
Published in American journal of human genetics (01-11-2005)“…Mutation of the human genome ranges from single base-pair changes to whole-chromosome aneuploidy. Karyotyping, fluorescence in situ hybridization, and…”
Get full text
Journal Article -
8
Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
Published in BMC bioinformatics (02-10-2007)“…Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur…”
Get full text
Journal Article -
9
High-throughput generation and engineering of recombinant human antibodies
Published in Journal of immunological methods (01-08-2001)“…The first version of the Human Combinatorial Antibody Library (HuCAL®) is a single-chain Fv-based phage display library (HuCAL®-scFv) with 2×10 9 members…”
Get full text
Journal Article -
10
PCD1, a novel gene containing PDZ and LIM domains, is overexpressed in several human cancers
Published in Cancer research (Chicago, Ill.) (15-09-2000)“…In an effort to discover novel genes differentially expressed in human pancreatic cancer, we have identified a gene named PCD1 (pancreatic cancer derived) that…”
Get full text
Journal Article -
11
Molecular profiling of dedicated lung cancer biopsy tissue sample collected at time of diagnostic bronchoscopy
Published in Journal of clinical oncology (01-06-2022)“…e20587 Background: The combined use of molecular biomarker testing and targeted precision therapeutics has led to improved survival in lung cancer. Broadening…”
Get full text
Journal Article -
12
DNA Copy Number Analysis in Gastrointestinal Stromal Tumors Using Gene Expression Microarrays
Published in Cancer informatics (01-01-2008)“…Cristina R. Antonescu1, Kai Wu2, Guoliang Leon Xing3, Manqiu Cao2, Yaron Turpaz4, Margaret A. Leversha5, Earl Hubbell3, Robert G. Maki6, C. Garrett Miyada7,…”
Get full text
Journal Article -
13
Detection of actionable molecular alterations through combined DNA/RNA molecular profiling of biopsies collected in early-stage lung cancer at time of diagnosis
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e20546 Background: Significant progress has been made in improving progression-free survival in lung cancer through the combination of molecular…”
Get full text
Journal Article -
14
Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14
Published in BMC genetics (30-12-2005)“…The data provided to the Genetic Analysis Workshop 14 (GAW 14) was the result of a collaboration among several different groups, catalyzed by Elizabeth Pugh…”
Get full text
Journal Article -
15
Analytical performance of a bronchial genomic classifier
Published in BMC cancer (26-02-2016)“…The current standard practice of lung lesion diagnosis often leads to inconclusive results, requiring additional diagnostic follow up procedures that are…”
Get full text
Journal Article -
16
A whole genome long-range haplotype (WGLRH) test for detecting imprints of positive selection in human populations
Published in Bioinformatics (01-09-2006)“…Motivation: The identification of signatures of positive selection can provide important insights into recent evolutionary history in human populations…”
Get full text
Journal Article -
17
Analysis of SNP content of 82 common copy-number polymorphisms from the Database of Genomic Variations
Published in American journal of human genetics (01-04-2006)Get full text
Journal Article -
18
Reply to Wirtenberger et al
Published in American journal of human genetics (01-04-2006)“…Even with modifications in SNP selection, the current algorithm implemented in CNAT (Affymetrix) would still need to be modified, because it compares…”
Get full text
Journal Article -
19
DNA Copy Number Analysis in Gastrointestinal Stromal Tumors Using Gene Expression Microarrays
Published in Cancer informatics (01-01-2008)“…We report a method, Expression-Microarray Copy Number Analysis (ECNA) for the detection of copy number changes using Affymetrix Human Genome U133 Plus 2.0…”
Get full text
Journal Article -
20
A genome-wide linkage analysis of alcoholism on microsatellite and single-nucleotide polymorphism data, using alcohol dependence phenotypes and electroencephalogram measures
Published in BMC genetics (30-12-2005)“…The Collaborative Study on the Genetics of Alcoholism (COGA) is a large-scale family study designed to identify genes that affect the risk for alcoholism and…”
Get full text
Journal Article