Search Results - "Cao, Julia X."
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Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets
Published in Diabetes (New York, N.Y.) (01-12-2010)“…The clinical effectiveness of parenterally-administered glucagon-like peptide-1 (GLP-1) mimetics to improve glucose control in patients suffering from type 2…”
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Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo
Published in The Journal of biological chemistry (14-08-2015)“…Insulin-degrading enzyme (IDE, insulysin) is the best characterized catabolic enzyme implicated in proteolysis of insulin. Recently, a peptide inhibitor of IDE…”
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Internalization and localization of basal insulin peglispro in cells
Published in Molecular and cellular endocrinology (15-10-2017)“…Basal insulin peglispro (BIL) is a novel, PEGylated insulin lispro that has a large hydrodynamic size compared with insulin lispro. It has a prolonged duration…”
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Specific Reduction of Hepatic Glucose 6-Phosphate Transporter-1 Ameliorates Diabetes while Avoiding Complications of Glycogen Storage Disease
Published in The Journal of biological chemistry (29-06-2007)“…d-Glucose-6-phosphatase is a key regulator of endogenous glucose production, and its inhibition may improve glucose control in type 2 diabetes. Herein,…”
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Structure and promoter characterization of aldo–keto reductase family 1 B10 gene
Published in Gene (15-05-2009)“…Aldo–keto reductase family 1 member B10 ( AKR1B10) is overexpressed in human hepatocellular carcinoma, lung squamous carcinoma, and lung adenocarcinoma in…”
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