Search Results - "Canuto, Gisele A.B."
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Identification of antioxidant and antimicrobial compounds from the oilseed crop Ricinus communis using a multiplatform metabolite profiling approach
Published in Industrial crops and products (15-11-2018)“…[Display omitted] •Antioxidant activity, total phenolic content and antimicrobial activity were assessed.•NMR, LC–MS and GC–MS were applied for the…”
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Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania
Published in Analytical and bioanalytical chemistry (01-05-2014)“…Miltefosine (MT) (hexadecylphosphocholine) was implemented to cope with resistance against antimonials, the classical treatment in Leishmaniasis. Given the…”
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Piper anisum as a promising new source of bioactive metabolites
Published in Chemical papers (01-05-2020)“…Piper species are commonly used by indigenous communities to treat several gastrointestinal diseases. In China, they are also used as an active ingredient in…”
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Chemical Diversity of Secondary Metabolites Produced by Brazilian Endophytic Fungi
Published in Current microbiology (2021)“…Endophytes are microorganisms that live inside vegetal tissues without causing any loss to the host plant. They display wide biosynthetic capacity when…”
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Development and validation of a liquid chromatography method for anthocyanins in strawberry (Fragaria spp.) and complementary studies on stability, kinetics and antioxidant power
Published in Food chemistry (01-02-2016)“…•A RPLC-DAD method was developed for inspection of 8 anthocyanins in strawberry.•A fully method validation for 8 anthocyanins with authentic standards was…”
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A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantum
Published in PloS one (10-07-2015)“…There is a rising resistance against antimony drugs, the gold-standard for treatment until some years ago. That is a serious problem due to the paucity of…”
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CE-ESI-MS metabolic fingerprinting of Leishmania resistance to antimony treatment
Published in Electrophoresis (01-07-2012)“…Metabolomics has become an invaluable tool to unveil biology of pathogens, with immediate application to chemotherapy. It is currently accepted that there is…”
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Capillary electrophoresis reveals polyamine metabolism modulation in Leishmania (Leishmania) amazonensis wild-type and arginase-knockout mutants under arginine starvation
Published in Electrophoresis (01-09-2015)“…l‐Arginine is an essential amino acid in Leishmania (Leishmania) amazonensis metabolism. A key enzyme for parasite l‐arginine metabolism is arginase (ARG) that…”
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Critical Factors in Sample Collection and Preparation for Clinical Metabolomics of Underexplored Biological Specimens
Published in Metabolites (01-01-2024)“…This review article compiles critical pre-analytical factors for sample collection and extraction of eight uncommon or underexplored biological specimens…”
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Neglected diseases prioritized in Brazil under the perspective of metabolomics: A review
Published in Electrophoresis (01-09-2015)“…This review article compiles in a critical manner literature publications regarding seven neglected diseases (ND) prioritized in Brazil (Chagas disease,…”
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Untargeted Metabolomics Insights into Newborns with Congenital Zika Infection
Published in Pathogens (Basel) (13-04-2021)“…Zika virus (ZIKV), an emerging virus belonging to the Flaviviridae family, causes severe neurological clinical complications and has been associated with…”
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