Search Results - "Canudas, A.M"

Wnt pathway regulation by long-term moderate exercise in rat hippocampus by Bayod, S, Menella, I, Sanchez-Roige, S, Lalanza, J.F, Escorihuela, R.M, Camins, A, Pallàs, M, Canudas, A.M

“…Abstract An active lifestyle involving regular exercise reduces the deleterious effects of the aging process. At the cerebral level, both synaptic plasticity…”
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Modulation of SIRT1 expression in different neurodegenerative models and human pathologies by Pallàs, M, Pizarro, J.G, Gutierrez-Cuesta, J, Crespo-Biel, N, Alvira, D, Tajes, M, Yeste-Velasco, M, Folch, J, Canudas, A.M, Sureda, F.X, Ferrer, I, Camins, A

“…Abstract We examined the expression of SIRT1 in several experimental paradigms of human pathologies. We used a neuroblastoma cell line (B65), neuronal primary…”
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Comparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex I and potassium deprivation in cerebellar neurons by Alvira, D, Yeste-Velasco, M, Folch, J, Verdaguer, E, Canudas, A.M, Pallàs, M, Camins, A

“…Abstract The mechanism involved in neuronal apoptosis is largely unknown. Studies performed on neuronal cell cultures provide information about the pathways…”
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Corrigendum to: Wnt pathway regulation by long-term moderate exercise in rat hippocampus [Brain Res. 1543 (2014) 38–48] by Bayod, S, Mennella, I, Sanchez-Roige, S, Lalanza, J.F, Escorihuela, R.M, Camins, A, Pallàs, M, Canudas, A.M

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Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium by Jordà, E.G., Verdaguer, E., Canudas, A.M., Jiménez, A., De Arriba, S. Garcia, Allgaier, C., Pallàs, M., Camins, A.

“…Although numerous studies have demonstrated a neuroprotective and anti-apoptotic role of lithium in neuronal cell cultures, the precise mechanism by which this…”
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Resveratrol modulates response against acute inflammatory stimuli in aged mouse brain by Palomera-Ávalos, V., Griñán-Ferré, C., Izquierdo, V., Camins, A., Sanfeliu, C., Canudas, A.M., Pallàs, M.

“…With upcoming age, the capability to fight against harmful stimuli decreases and the organism becomes more susceptible to infections and diseases. Here, the…”
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Long-term physical exercise induces changes in sirtuin 1 pathway and oxidative parameters in adult rat tissues by Bayod, S., del Valle, J., Lalanza, J.F., Sanchez-Roige, S., de Luxán-Delgado, B., Coto-Montes, A., Canudas, A.M., Camins, A., Escorihuela, R.M., Pallàs, M.

“…The protein deacetylase, sirtuin 1, is suggested as a master regulator of exercise-induced beneficial effects. Sirtuin 1 modulates mitochondrial biogenesis,…”
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Kainate induces AKT, ERK and cdk5/GSK3β pathway deregulation, phosphorylates tau protein in mouse hippocampus by Crespo-Biel, N., Canudas, A.M., Camins, A., Pallàs, M.

“…Acute treatment with kainate 30 mg/kg (KA) produced behavioral alterations and reactive gliosis. However, it did not produce major death of mouse hippocampal…”
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Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro by Crespo-Biel, N., Camins, A., Pallàs, M., Canudas, A.M.

“…Lithium reduced striatal neurodegeneration induced in rats by 3-nitropropionic acid inhibiting calpain activation. Lithium prevented an increase in cdk5…”
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Regulation of GSK-3β by calpain in the 3-nitropropionic acid model by Crespo-Biel, N., Camins, A., Gutiérrez-Cuesta, J., Melchiorri, D., Nicoletti, F., Pallàs, M., Canudas, A.M.

“…Glycogen synthase kinase‐3β (GSK‐3β) is a crucial component in the cascade of events that culminate in a range of neurodegenerative diseases. It is controlled…”
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Flavopiridol: an antitumor drug with potential application in the treatment of neurodegenerative diseases by Pallàs, M., Verdaguer, E., Jordà, E.G., Jiménez, A., Canudas, A.M., Camins, A.

“…Several lines of evidence show that cyclin-dependent kinases (CDKs) contribute to neurodegenerative disorders such as Alzheimer's and Parkinson's diseases, and…”
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(+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration by Jordá, E G, Verdaguer, E, Jiménez, A, Canudas, A M, Rimbau, V, Camps, P, Muñoz-Torrero, D, Camins, A, Pallàs, M

“…Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of Alzheimer's disease. They increase the levels of acetylcholine…”
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3-amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons by Verdaguer, E, Jordà, E.G, Canudas, A.M, Jiménez, A, Sureda, F.X, Rimbau, V, Pubill, D, Escubedo, E, Camarasa, J, Pallàs, M, Camins, A

“…The mechanisms underlying selective neuronal cell death in kainic acid-mediated neurodegeneration are not fully understood. We have recently demonstrated that…”
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