Search Results - "Cantrell, Lee S."
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Spatially Resolved Proteomic Analysis of the Lens Extracellular Diffusion Barrier
Published in Investigative ophthalmology & visual science (23-09-2021)“…The presence of a physical barrier to molecular diffusion through lenticular extracellular space has been repeatedly detected. This extracellular diffusion…”
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Lens Aquaporin-5 Inserts Into Bovine Fiber Cell Plasma Membranes Via Unconventional Protein Secretion
Published in Investigative ophthalmology & visual science (11-07-2022)“…PurposeTo spatially map aquaporin-5 (AQP5) expression in the bovine lens, molecularly characterize cytoplasmic AQP5-containing vesicles in the outer cortex,…”
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Proteome Remodeling of the Eye Lens at 50 Years Identified With Data-Independent Acquisition
Published in Molecular & cellular proteomics (01-01-2023)“…The eye lens is responsible for focusing and transmitting light to the retina. The lens does this in the absence of organelles, yet maintains transparency for…”
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Data-Independent Acquisition Mass Spectrometry of the Human Lens Enhances Spatiotemporal Measurement of Fiber Cell Aging
Published in Journal of the American Society for Mass Spectrometry (01-12-2021)“…The ocular lens proteome undergoes post-translational and progressive degradation as fiber cells age. The oldest fiber cells and the proteins therein are…”
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Proteomic characterization of the human lens and Cataractogenesis
Published in Expert review of proteomics (01-02-2021)“…The goal of this review is to highlight the triumphs and frontiers in measurement of the lens proteome as it relates to onset of age-related nuclear cataract…”
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Tissue fixation effects on human retinal lipid analysis by MALDI imaging and LC–MS/MS technologies
Published in Journal of mass spectrometry. (01-12-2021)“…Imaging mass spectrometry (IMS) allows the location and abundance of lipids to be mapped across tissue sections of human retina. For reproducible and accurate…”
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Differences in the utilization of palliative care support services among patients with metastatic solid tumor cancer in a community oncology setting: A retrospective review
Published in Journal of clinical oncology (01-10-2022)“…82 Background: Palliative care has been underutilized in the setting of advanced cancer despite its established benefit in improving the quality of life in…”
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